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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MPHOSPH10
Full Name:
U3 small nucleolar ribonucleoprotein protein MPP10
Alias:
M phase phosphoprotein 10; MPP10; MPP10P; U3 small nucleolar ribonucleoprotein MPP10
Type:
RNA binding protein
Mass (Da):
78864
Number AA:
681
UniProt ID:
O00566
International Prot ID:
IPI00012149
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0005732
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0031202
PhosphoSite+
KinaseNET
Biological Process:
GO:0000375
GO:0006364
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
P
Q
V
W
R
R
R
T
L
E
R
C
L
T
E
Site 2
T16
R
T
L
E
R
C
L
T
E
V
G
K
A
T
G
Site 3
T22
L
T
E
V
G
K
A
T
G
R
P
E
C
F
L
Site 4
T30
G
R
P
E
C
F
L
T
I
Q
E
G
L
A
S
Site 5
S37
T
I
Q
E
G
L
A
S
K
F
T
S
L
T
K
Site 6
Y47
T
S
L
T
K
V
L
Y
D
F
N
K
I
L
E
Site 7
S61
E
N
G
R
I
H
G
S
P
L
Q
K
L
V
I
Site 8
Y90
Q
N
E
P
I
L
Q
Y
F
Q
N
A
V
S
E
Site 9
S105
T
I
N
D
E
D
I
S
L
L
P
E
S
E
E
Site 10
S110
D
I
S
L
L
P
E
S
E
E
Q
E
R
E
E
Site 11
S120
Q
E
R
E
E
D
G
S
E
I
E
A
D
D
K
Site 12
S139
D
L
E
E
E
E
V
S
D
M
G
N
D
D
P
Site 13
S156
G
E
R
A
E
N
S
S
K
S
D
L
R
K
S
Site 14
S158
R
A
E
N
S
S
K
S
D
L
R
K
S
P
V
Site 15
S163
S
K
S
D
L
R
K
S
P
V
F
S
D
E
D
Site 16
S167
L
R
K
S
P
V
F
S
D
E
D
S
D
L
D
Site 17
S171
P
V
F
S
D
E
D
S
D
L
D
F
D
I
S
Site 18
S178
S
D
L
D
F
D
I
S
K
L
E
Q
Q
S
K
Site 19
S198
Q
G
K
P
R
E
K
S
I
V
D
D
K
F
F
Site 20
Y213
K
L
S
E
M
E
A
Y
L
E
N
I
E
K
E
Site 21
S242
D
F
F
E
D
I
D
S
D
E
D
E
G
G
L
Site 22
S252
D
E
G
G
L
F
G
S
K
K
L
K
S
G
K
Site 23
S257
F
G
S
K
K
L
K
S
G
K
S
S
R
N
L
Site 24
S260
K
K
L
K
S
G
K
S
S
R
N
L
K
Y
K
Site 25
S261
K
L
K
S
G
K
S
S
R
N
L
K
Y
K
D
Site 26
Y266
K
S
S
R
N
L
K
Y
K
D
F
F
D
P
V
Site 27
S275
D
F
F
D
P
V
E
S
D
E
D
I
T
N
V
Site 28
T280
V
E
S
D
E
D
I
T
N
V
H
D
D
E
L
Site 29
S289
V
H
D
D
E
L
D
S
N
K
E
D
D
E
I
Site 30
S305
E
E
E
A
E
E
L
S
I
S
E
T
D
E
D
Site 31
S307
E
A
E
E
L
S
I
S
E
T
D
E
D
D
D
Site 32
T309
E
E
L
S
I
S
E
T
D
E
D
D
D
L
Q
Site 33
S327
D
N
K
Q
H
K
E
S
L
K
R
V
T
F
A
Site 34
T332
K
E
S
L
K
R
V
T
F
A
L
P
D
D
A
Site 35
T344
D
D
A
E
T
E
D
T
G
V
L
N
V
K
K
Site 36
S353
V
L
N
V
K
K
N
S
D
E
V
K
S
S
F
Site 37
S358
K
N
S
D
E
V
K
S
S
F
E
K
R
Q
E
Site 38
S359
N
S
D
E
V
K
S
S
F
E
K
R
Q
E
K
Site 39
S373
K
M
N
E
K
I
A
S
L
E
K
E
L
L
E
Site 40
S399
A
Q
K
R
P
E
N
S
L
L
E
E
T
L
H
Site 41
T418
V
R
M
A
P
V
I
T
E
E
T
T
L
Q
L
Site 42
Y452
E
K
P
K
E
D
A
Y
E
Y
K
K
R
L
T
Site 43
Y454
P
K
E
D
A
Y
E
Y
K
K
R
L
T
L
D
Site 44
T459
Y
E
Y
K
K
R
L
T
L
D
H
E
K
S
K
Site 45
S465
L
T
L
D
H
E
K
S
K
L
S
L
A
E
I
Site 46
S468
D
H
E
K
S
K
L
S
L
A
E
I
Y
E
Q
Site 47
T565
N
K
A
G
D
I
K
T
A
A
E
K
T
A
T
Site 48
T572
T
A
A
E
K
T
A
T
D
K
K
R
E
R
R
Site 49
Y583
R
E
R
R
K
K
K
Y
Q
K
R
M
K
I
K
Site 50
S602
R
R
K
L
L
E
K
S
S
V
D
Q
A
G
K
Site 51
S603
R
K
L
L
E
K
S
S
V
D
Q
A
G
K
Y
Site 52
S611
V
D
Q
A
G
K
Y
S
K
T
V
A
S
E
K
Site 53
T613
Q
A
G
K
Y
S
K
T
V
A
S
E
K
L
K
Site 54
T625
K
L
K
Q
L
T
K
T
G
K
A
S
F
I
K
Site 55
S629
L
T
K
T
G
K
A
S
F
I
K
D
E
G
K
Site 56
S642
G
K
D
K
A
L
K
S
S
Q
A
F
F
S
K
Site 57
S643
K
D
K
A
L
K
S
S
Q
A
F
F
S
K
L
Site 58
S675
K
K
K
R
Q
D
I
S
V
H
K
L
K
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation