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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARPC1B
Full Name:
Actin-related protein 2/3 complex subunit 1B
Alias:
Actin related protein 2/3 complex, subunit 1A (41 kD); Actin related protein 2/3 complex, subunit 1B, 41kDa; ARC1B; ARC41; Arp2/3 complex 41 kDa subunit; ARP2/3 protein complex subunit p41; P40-ARC; P41-ARC
Type:
Motility/polarity/chemotaxis; Cytoskeletal protein
Mass (Da):
40950
Number AA:
372
UniProt ID:
O15143
International Prot ID:
IPI00005160
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005885
GO:0005737
GO:0005885
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005200
GO:0005200
PhosphoSite+
KinaseNET
Biological Process:
GO:0006928
GO:0030833
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
H
A
W
N
K
D
R
T
Q
I
A
I
C
P
N
Site 2
Y35
N
N
H
E
V
H
I
Y
E
K
S
G
A
K
W
Site 3
T69
P
E
S
N
R
I
V
T
C
G
T
D
R
N
A
Site 4
Y77
C
G
T
D
R
N
A
Y
V
W
T
L
K
G
R
Site 5
T89
K
G
R
T
W
K
P
T
L
V
I
L
R
I
N
Site 6
S121
G
S
G
S
R
V
I
S
I
C
Y
F
E
Q
E
Site 7
Y124
S
R
V
I
S
I
C
Y
F
E
Q
E
N
D
W
Site 8
S143
H
I
K
K
P
I
R
S
T
V
L
S
L
D
W
Site 9
T144
I
K
K
P
I
R
S
T
V
L
S
L
D
W
H
Site 10
S147
P
I
R
S
T
V
L
S
L
D
W
H
P
N
N
Site 11
S170
D
F
K
C
R
I
F
S
A
Y
I
K
E
V
E
Site 12
Y172
K
C
R
I
F
S
A
Y
I
K
E
V
E
E
R
Site 13
T183
V
E
E
R
P
A
P
T
P
W
G
S
K
M
P
Site 14
S187
P
A
P
T
P
W
G
S
K
M
P
F
G
E
L
Site 15
S199
G
E
L
M
F
E
S
S
S
S
C
G
W
V
H
Site 16
S200
E
L
M
F
E
S
S
S
S
C
G
W
V
H
G
Site 17
S292
L
D
V
P
K
Q
S
S
Q
R
G
L
T
A
R
Site 18
T297
Q
S
S
Q
R
G
L
T
A
R
E
R
F
Q
N
Site 19
S310
Q
N
L
D
K
K
A
S
S
E
G
G
T
A
A
Site 20
S311
N
L
D
K
K
A
S
S
E
G
G
T
A
A
G
Site 21
T315
K
A
S
S
E
G
G
T
A
A
G
A
G
L
D
Site 22
S323
A
A
G
A
G
L
D
S
L
H
K
N
S
V
S
Site 23
S328
L
D
S
L
H
K
N
S
V
S
Q
I
S
V
L
Site 24
S330
S
L
H
K
N
S
V
S
Q
I
S
V
L
S
G
Site 25
S333
K
N
S
V
S
Q
I
S
V
L
S
G
G
K
A
Site 26
S336
V
S
Q
I
S
V
L
S
G
G
K
A
K
C
S
Site 27
S343
S
G
G
K
A
K
C
S
Q
F
C
T
T
G
M
Site 28
S355
T
G
M
D
G
G
M
S
I
W
D
V
K
S
L
Site 29
S361
M
S
I
W
D
V
K
S
L
E
S
A
L
K
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation