PhosphoNET

           
Protein Info 
   
Short Name:  KCNN4
Full Name:  Intermediate conductance calcium-activated potassium channel protein 4
Alias:  IK1; IKCa1; KCa3.1; KCA4; KCa4; KCN4; Potassium intermediate/small conductance calcium-activated channel subfamily N member 4; Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4; Putative Gardos channel; SK4
Type:  Uncharacterized protein
Mass (Da):  47696
Number AA:  427
UniProt ID:  O15554
International Prot ID:  IPI00032466
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0008076     Uniprot OncoNet
Molecular Function:  GO:0015269  GO:0005516   PhosphoSite+ KinaseNET
Biological Process:  GO:0006952  GO:0006813   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T101RDWRVALTGRQAAQI
Site 2T136QDLGAPLTSPQPWPG
Site 3S137DLGAPLTSPQPWPGF
Site 4Y307NFMMDIQYTKEMKES
Site 5S314YTKEMKESAARVLQE
Site 6T329AWMFYKHTRRKESHA
Site 7S334KHTRRKESHAARRHQ
Site 8S367KLREQVNSMVDISKM
Site 9Y379SKMHMILYDLQQNLS
Site 10S386YDLQQNLSSSHRALE
Site 11S388LQQNLSSSHRALEKQ
Site 12T398ALEKQIDTLAGKLDA
Site 13S411DALTELLSTALGPRQ
Site 14S423PRQLPEPSQQSK___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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