PhosphoNET

           
Protein Info 
   
Short Name:  AIRE
Full Name:  Autoimmune regulator
Alias:  AIRE1; APECED; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy; PGA1
Type:  Transcription factor
Mass (Da):  57730
Number AA: 
UniProt ID:  O43918
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0003682  GO:0042393  GO:0010843 PhosphoSite+ KinaseNET
Biological Process:  GO:0006355  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T68ALLSWLLTQDSTAIL
Site 2Y85WRVLFKDYNLERYGR
Site 3Y90KDYNLERYGRLQPIL
Site 4S99RLQPILDSFPKDVDL
Site 5S107FPKDVDLSQPRKGRK
Site 6T130VPPPRLPTKRKASEE
Site 7S135LPTKRKASEEARAAA
Site 8T151AALTPRGTASPGSQL
Site 9S153LTPRGTASPGSQLKA
Site 10S156RGTASPGSQLKAKPP
Site 11S168KPPKKPESSAEQQRL
Site 12T183PLGNGIQTMSASVQR
Site 13S185GNGIQTMSASVQRAV
Site 14S187GIQTMSASVQRAVAM
Site 15S220QVFESGGSKKCIQVG
Site 16T232QVGGEFYTPSKFEDS
Site 17S234GGEFYTPSKFEDSGS
Site 18S239TPSKFEDSGSGKNKA
Site 19S241SKFEDSGSGKNKARS
Site 20S248SGKNKARSSSGPKPL
Site 21S249GKNKARSSSGPKPLV
Site 22S250KNKARSSSGPKPLVR
Site 23S287PAPLALPSDPQLHQK
Site 24S332PPLREIPSGTWRCSS
Site 25T334LREIPSGTWRCSSCL
Site 26S338PSGTWRCSSCLQATV
Site 27S339SGTWRCSSCLQATVQ
Site 28T364PQEPPVETPLPPGLR
Site 29T390EPLAGMDTTLVYKHL
Site 30Y394GMDTTLVYKHLPAPP
Site 31S402KHLPAPPSAAPLPGL
Site 32T463RCHFPAGTSRPGTGL
Site 33T468AGTSRPGTGLRCRSC
Site 34S474GTGLRCRSCSGDVTP
Site 35S476GLRCRSCSGDVTPAP
Site 36T480RSCSGDVTPAPVEGV
Site 37T504PGPAKDDTASHEPAL
Site 38S506PAKDDTASHEPALHR
Site 39S518LHRDDLESLLSEHTF
Site 40S521DDLESLLSEHTFDGI
Site 41T524ESLLSEHTFDGILQW
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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