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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UGDH
Full Name:
UDP-glucose 6-dehydrogenase
Alias:
GDH; UDPGDH; UDP-Glc dehydrogenase; UDP-GlcDH; UDP-glucose dehydrogenase; UGD; Uridine diphospho-glucose dehydrogenase
Type:
Oxidoreductase; Carbohydrate Metabolism - pentose and glucuronate interconversions; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - ascorbate and aldarate; EC 1.1.1.22
Mass (Da):
55024
Number AA:
494
UniProt ID:
O60701
International Prot ID:
IPI00031420
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0051287
GO:0003979
GO:0009055
PhosphoSite+
KinaseNET
Biological Process:
GO:0006011
GO:0006065
GO:0006024
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S47
S
R
I
N
A
W
N
S
P
T
L
P
I
Y
E
Site 2
Y53
N
S
P
T
L
P
I
Y
E
P
G
L
K
E
V
Site 3
S63
G
L
K
E
V
V
E
S
C
R
G
K
N
L
F
Site 4
S88
E
A
D
L
V
F
I
S
V
N
T
P
T
K
T
Site 5
T91
L
V
F
I
S
V
N
T
P
T
K
T
Y
G
M
Site 6
T95
S
V
N
T
P
T
K
T
Y
G
M
G
K
G
R
Site 7
Y108
G
R
A
A
D
L
K
Y
I
E
A
C
A
R
R
Site 8
S120
A
R
R
I
V
Q
N
S
N
G
Y
K
I
V
T
Site 9
S130
Y
K
I
V
T
E
K
S
T
V
P
V
R
A
A
Site 10
T148
R
R
I
F
D
A
N
T
K
P
N
L
N
L
Q
Site 11
S158
N
L
N
L
Q
V
L
S
N
P
E
F
L
A
E
Site 12
T185
V
L
I
G
G
D
E
T
P
E
G
Q
R
A
V
Site 13
T210
V
P
R
E
K
I
L
T
T
N
T
W
S
S
E
Site 14
T211
P
R
E
K
I
L
T
T
N
T
W
S
S
E
L
Site 15
T213
E
K
I
L
T
T
N
T
W
S
S
E
L
S
K
Site 16
S219
N
T
W
S
S
E
L
S
K
L
A
A
N
A
F
Site 17
T253
A
D
V
E
E
V
A
T
A
I
G
M
D
Q
R
Site 18
Y299
N
L
P
E
V
A
R
Y
W
Q
Q
V
I
D
M
Site 19
Y309
Q
V
I
D
M
N
D
Y
Q
R
R
R
F
A
S
Site 20
S316
Y
Q
R
R
R
F
A
S
R
I
I
D
S
L
F
Site 21
T342
G
F
A
F
K
K
D
T
G
D
T
R
E
S
S
Site 22
T345
F
K
K
D
T
G
D
T
R
E
S
S
S
I
Y
Site 23
S348
D
T
G
D
T
R
E
S
S
S
I
Y
I
S
K
Site 24
S349
T
G
D
T
R
E
S
S
S
I
Y
I
S
K
Y
Site 25
S350
G
D
T
R
E
S
S
S
I
Y
I
S
K
Y
L
Site 26
Y352
T
R
E
S
S
S
I
Y
I
S
K
Y
L
M
D
Site 27
S354
E
S
S
S
I
Y
I
S
K
Y
L
M
D
E
G
Site 28
Y356
S
S
I
Y
I
S
K
Y
L
M
D
E
G
A
H
Site 29
Y367
E
G
A
H
L
H
I
Y
D
P
K
V
P
R
E
Site 30
S381
E
Q
I
V
V
D
L
S
H
P
G
V
S
E
D
Site 31
S392
V
S
E
D
D
Q
V
S
R
L
V
T
I
S
K
Site 32
T396
D
Q
V
S
R
L
V
T
I
S
K
D
P
Y
E
Site 33
S398
V
S
R
L
V
T
I
S
K
D
P
Y
E
A
C
Site 34
Y402
V
T
I
S
K
D
P
Y
E
A
C
D
G
A
H
Site 35
Y425
D
M
F
K
E
L
D
Y
E
R
I
H
K
K
M
Site 36
T461
T
I
G
F
Q
I
E
T
I
G
K
K
V
S
S
Site 37
S467
E
T
I
G
K
K
V
S
S
K
R
I
P
Y
A
Site 38
S468
T
I
G
K
K
V
S
S
K
R
I
P
Y
A
P
Site 39
Y473
V
S
S
K
R
I
P
Y
A
P
S
G
E
I
P
Site 40
S476
K
R
I
P
Y
A
P
S
G
E
I
P
K
F
S
Site 41
S483
S
G
E
I
P
K
F
S
L
Q
D
P
P
N
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation