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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PHF14
Full Name:
PHD finger protein 14
Alias:
HCG_17398; KIAA0783; PHFE
Type:
Unknown function
Mass (Da):
100081
Number AA:
888
UniProt ID:
O94880
International Prot ID:
IPI00454969
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
Q
V
K
P
L
A
A
S
L
L
E
A
L
D
Y
Site 2
Y23
S
L
L
E
A
L
D
Y
D
S
S
D
D
S
D
Site 3
S25
L
E
A
L
D
Y
D
S
S
D
D
S
D
F
K
Site 4
S26
E
A
L
D
Y
D
S
S
D
D
S
D
F
K
V
Site 5
S29
D
Y
D
S
S
D
D
S
D
F
K
V
G
D
A
Site 6
S37
D
F
K
V
G
D
A
S
D
S
E
G
S
G
N
Site 7
S39
K
V
G
D
A
S
D
S
E
G
S
G
N
G
S
Site 8
S46
S
E
G
S
G
N
G
S
E
D
A
S
K
D
S
Site 9
S50
G
N
G
S
E
D
A
S
K
D
S
G
E
G
S
Site 10
S53
S
E
D
A
S
K
D
S
G
E
G
S
C
S
D
Site 11
S57
S
K
D
S
G
E
G
S
C
S
D
S
E
E
N
Site 12
S59
D
S
G
E
G
S
C
S
D
S
E
E
N
I
L
Site 13
S61
G
E
G
S
C
S
D
S
E
E
N
I
L
E
E
Site 14
S91
S
A
E
E
E
V
L
S
S
E
K
Q
L
I
K
Site 15
S92
A
E
E
E
V
L
S
S
E
K
Q
L
I
K
M
Site 16
S156
A
A
T
T
P
A
T
S
P
P
A
V
N
T
S
Site 17
S163
S
P
P
A
V
N
T
S
P
S
V
P
T
T
T
Site 18
S165
P
A
V
N
T
S
P
S
V
P
T
T
T
T
A
Site 19
T169
T
S
P
S
V
P
T
T
T
T
A
T
E
E
Q
Site 20
S196
R
P
L
L
D
F
V
S
M
E
E
L
N
D
M
Site 21
Y206
E
L
N
D
M
D
D
Y
D
S
E
D
D
N
D
Site 22
S208
N
D
M
D
D
Y
D
S
E
D
D
N
D
W
R
Site 23
T217
D
D
N
D
W
R
P
T
V
V
K
R
K
G
R
Site 24
S227
K
R
K
G
R
S
A
S
Q
K
E
G
S
D
G
Site 25
S232
S
A
S
Q
K
E
G
S
D
G
D
N
E
D
D
Site 26
S244
E
D
D
E
D
E
G
S
G
S
D
E
D
E
N
Site 27
S246
D
E
D
E
G
S
G
S
D
E
D
E
N
D
E
Site 28
S260
E
G
N
D
E
D
H
S
S
P
A
S
E
G
G
Site 29
S261
G
N
D
E
D
H
S
S
P
A
S
E
G
G
C
Site 30
S264
E
D
H
S
S
P
A
S
E
G
G
C
K
K
K
Site 31
S273
G
G
C
K
K
K
K
S
K
V
L
S
R
N
S
Site 32
S277
K
K
K
S
K
V
L
S
R
N
S
A
D
D
E
Site 33
S280
S
K
V
L
S
R
N
S
A
D
D
E
E
L
T
Site 34
T287
S
A
D
D
E
E
L
T
N
D
S
L
T
L
S
Site 35
S290
D
E
E
L
T
N
D
S
L
T
L
S
Q
S
K
Site 36
T292
E
L
T
N
D
S
L
T
L
S
Q
S
K
S
N
Site 37
S294
T
N
D
S
L
T
L
S
Q
S
K
S
N
E
D
Site 38
S296
D
S
L
T
L
S
Q
S
K
S
N
E
D
S
L
Site 39
S298
L
T
L
S
Q
S
K
S
N
E
D
S
L
I
L
Site 40
S302
Q
S
K
S
N
E
D
S
L
I
L
E
K
S
Q
Site 41
S308
D
S
L
I
L
E
K
S
Q
N
W
S
S
Q
K
Site 42
S313
E
K
S
Q
N
W
S
S
Q
K
M
D
H
I
L
Site 43
Y351
I
T
V
H
E
G
C
Y
G
V
D
G
E
S
D
Site 44
S357
C
Y
G
V
D
G
E
S
D
S
I
M
S
S
A
Site 45
S359
G
V
D
G
E
S
D
S
I
M
S
S
A
S
E
Site 46
S363
E
S
D
S
I
M
S
S
A
S
E
N
S
T
E
Site 47
S365
D
S
I
M
S
S
A
S
E
N
S
T
E
P
W
Site 48
S368
M
S
S
A
S
E
N
S
T
E
P
W
F
C
D
Site 49
T369
S
S
A
S
E
N
S
T
E
P
W
F
C
D
A
Site 50
T427
I
D
K
L
R
P
V
T
L
T
E
M
N
Y
S
Site 51
T429
K
L
R
P
V
T
L
T
E
M
N
Y
S
K
Y
Site 52
Y436
T
E
M
N
Y
S
K
Y
G
A
K
E
C
S
F
Site 53
S442
K
Y
G
A
K
E
C
S
F
C
E
D
P
R
F
Site 54
S479
A
Q
K
E
G
L
L
S
E
A
A
A
E
E
D
Site 55
Y511
R
K
W
K
R
K
N
Y
L
A
L
Q
S
Y
C
Site 56
Y517
N
Y
L
A
L
Q
S
Y
C
K
M
S
L
Q
E
Site 57
S530
Q
E
R
E
K
Q
L
S
P
E
A
Q
A
R
I
Site 58
S553
A
K
A
E
L
A
R
S
T
R
P
Q
A
W
V
Site 59
T554
K
A
E
L
A
R
S
T
R
P
Q
A
W
V
P
Site 60
T570
E
K
L
P
R
P
L
T
S
S
A
S
A
I
R
Site 61
S571
K
L
P
R
P
L
T
S
S
A
S
A
I
R
K
Site 62
S572
L
P
R
P
L
T
S
S
A
S
A
I
R
K
L
Site 63
S574
R
P
L
T
S
S
A
S
A
I
R
K
L
M
R
Site 64
S598
D
I
F
P
V
D
N
S
D
T
S
S
S
V
D
Site 65
T600
F
P
V
D
N
S
D
T
S
S
S
V
D
G
R
Site 66
S601
P
V
D
N
S
D
T
S
S
S
V
D
G
R
R
Site 67
S602
V
D
N
S
D
T
S
S
S
V
D
G
R
R
K
Site 68
S603
D
N
S
D
T
S
S
S
V
D
G
R
R
K
H
Site 69
Y622
L
T
A
D
F
V
N
Y
Y
F
E
R
N
M
R
Site 70
Y623
T
A
D
F
V
N
Y
Y
F
E
R
N
M
R
M
Site 71
S664
E
Y
N
K
L
C
E
S
L
E
E
L
Q
N
L
Site 72
S709
A
P
K
E
R
K
P
S
K
K
E
G
G
T
Q
Site 73
S719
E
G
G
T
Q
K
T
S
T
L
P
A
V
L
Y
Site 74
T720
G
G
T
Q
K
T
S
T
L
P
A
V
L
Y
S
Site 75
T760
G
C
L
D
P
P
L
T
R
M
P
R
K
T
K
Site 76
T766
L
T
R
M
P
R
K
T
K
N
S
Y
W
Q
C
Site 77
Y770
P
R
K
T
K
N
S
Y
W
Q
C
S
E
C
D
Site 78
S782
E
C
D
Q
A
G
S
S
D
M
E
A
D
M
A
Site 79
T792
E
A
D
M
A
M
E
T
L
P
D
G
T
K
R
Site 80
S800
L
P
D
G
T
K
R
S
R
R
Q
I
K
E
P
Site 81
T827
K
K
I
P
I
R
N
T
R
T
R
G
R
K
R
Site 82
S835
R
T
R
G
R
K
R
S
F
V
P
E
E
E
K
Site 83
S856
R
E
R
R
Q
R
Q
S
V
L
Q
K
K
P
K
Site 84
T869
P
K
A
E
D
L
R
T
E
C
A
T
C
K
G
Site 85
T873
D
L
R
T
E
C
A
T
C
K
G
T
G
D
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation