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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FKBP9
Full Name:
Peptidyl-prolyl cis-trans isomerase FKBP9
Alias:
FK506 binding protein 9, 63 kDa; FK506-binding protein 9; FKBP60; FKBP63; Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase
Type:
Isomerase; Endoplasmic reticulum; EC 5.2.1.8; Calcium-binding protein
Mass (Da):
63065
Number AA:
570
UniProt ID:
O95302
International Prot ID:
IPI00182126
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0003755
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T50
V
P
D
E
C
P
R
T
V
R
S
G
D
F
V
Site 2
Y59
R
S
G
D
F
V
R
Y
H
Y
V
G
T
F
P
Site 3
Y61
G
D
F
V
R
Y
H
Y
V
G
T
F
P
D
G
Site 4
T64
V
R
Y
H
Y
V
G
T
F
P
D
G
Q
K
F
Site 5
S73
P
D
G
Q
K
F
D
S
S
Y
D
R
D
S
T
Site 6
S74
D
G
Q
K
F
D
S
S
Y
D
R
D
S
T
F
Site 7
Y75
G
Q
K
F
D
S
S
Y
D
R
D
S
T
F
N
Site 8
S79
D
S
S
Y
D
R
D
S
T
F
N
V
F
V
G
Site 9
T80
S
S
Y
D
R
D
S
T
F
N
V
F
V
G
K
Site 10
Y117
K
I
P
P
K
L
A
Y
G
N
E
G
V
S
G
Site 11
S123
A
Y
G
N
E
G
V
S
G
V
I
P
P
N
S
Site 12
T152
E
D
Q
V
Q
I
H
T
Y
F
K
P
P
S
C
Site 13
Y153
D
Q
V
Q
I
H
T
Y
F
K
P
P
S
C
P
Site 14
T162
K
P
P
S
C
P
R
T
I
Q
V
S
D
F
V
Site 15
Y171
Q
V
S
D
F
V
R
Y
H
Y
N
G
T
F
L
Site 16
Y173
S
D
F
V
R
Y
H
Y
N
G
T
F
L
D
G
Site 17
T176
V
R
Y
H
Y
N
G
T
F
L
D
G
T
L
F
Site 18
T181
N
G
T
F
L
D
G
T
L
F
D
S
S
H
N
Site 19
S185
L
D
G
T
L
F
D
S
S
H
N
R
M
K
T
Site 20
S186
D
G
T
L
F
D
S
S
H
N
R
M
K
T
Y
Site 21
T192
S
S
H
N
R
M
K
T
Y
D
T
Y
V
G
I
Site 22
Y193
S
H
N
R
M
K
T
Y
D
T
Y
V
G
I
G
Site 23
Y229
T
I
P
P
F
L
A
Y
G
E
D
G
D
G
K
Site 24
S259
D
L
H
N
P
K
D
S
I
S
I
E
N
K
V
Site 25
S261
H
N
P
K
D
S
I
S
I
E
N
K
V
V
P
Site 26
S275
P
E
N
C
E
R
I
S
Q
S
G
D
F
L
R
Site 27
S277
N
C
E
R
I
S
Q
S
G
D
F
L
R
Y
H
Site 28
Y283
Q
S
G
D
F
L
R
Y
H
Y
N
G
T
L
L
Site 29
Y285
G
D
F
L
R
Y
H
Y
N
G
T
L
L
D
G
Site 30
T293
N
G
T
L
L
D
G
T
L
F
D
S
S
Y
S
Site 31
S297
L
D
G
T
L
F
D
S
S
Y
S
R
N
R
T
Site 32
S298
D
G
T
L
F
D
S
S
Y
S
R
N
R
T
F
Site 33
Y299
G
T
L
F
D
S
S
Y
S
R
N
R
T
F
D
Site 34
T304
S
S
Y
S
R
N
R
T
F
D
T
Y
I
G
Q
Site 35
T307
S
R
N
R
T
F
D
T
Y
I
G
Q
G
Y
V
Site 36
Y308
R
N
R
T
F
D
T
Y
I
G
Q
G
Y
V
I
Site 37
Y313
D
T
Y
I
G
Q
G
Y
V
I
P
G
M
D
E
Site 38
S368
V
I
D
F
H
N
P
S
D
S
I
S
I
T
S
Site 39
S370
D
F
H
N
P
S
D
S
I
S
I
T
S
H
Y
Site 40
S372
H
N
P
S
D
S
I
S
I
T
S
H
Y
K
P
Site 41
T374
P
S
D
S
I
S
I
T
S
H
Y
K
P
P
D
Site 42
S375
S
D
S
I
S
I
T
S
H
Y
K
P
P
D
C
Site 43
Y377
S
I
S
I
T
S
H
Y
K
P
P
D
C
S
V
Site 44
S383
H
Y
K
P
P
D
C
S
V
L
S
K
K
G
D
Site 45
S386
P
P
D
C
S
V
L
S
K
K
G
D
Y
L
K
Site 46
Y391
V
L
S
K
K
G
D
Y
L
K
Y
H
Y
N
A
Site 47
Y394
K
K
G
D
Y
L
K
Y
H
Y
N
A
S
L
L
Site 48
Y396
G
D
Y
L
K
Y
H
Y
N
A
S
L
L
D
G
Site 49
T404
N
A
S
L
L
D
G
T
L
L
D
S
T
W
N
Site 50
S408
L
D
G
T
L
L
D
S
T
W
N
L
G
K
T
Site 51
T409
D
G
T
L
L
D
S
T
W
N
L
G
K
T
Y
Site 52
T415
S
T
W
N
L
G
K
T
Y
N
I
V
L
G
S
Site 53
Y416
T
W
N
L
G
K
T
Y
N
I
V
L
G
S
G
Site 54
S493
F
I
W
N
G
E
V
S
P
N
L
F
E
E
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation