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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Zic2
Full Name:
Zinc finger protein ZIC 2
Alias:
Zinc finger protein of the cerebellum 2
Type:
Intracellular, Nucleus protein
Mass (Da):
55006
Number AA:
532
UniProt ID:
O95409
International Prot ID:
IPI00030652
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007420
GO:0030154
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
F
P
A
I
G
V
G
S
F
A
R
H
H
H
H
Site 2
S24
F
A
R
H
H
H
H
S
A
A
A
A
A
A
A
Site 3
S41
E
M
Q
D
R
E
L
S
L
A
A
A
Q
N
G
Site 4
S70
N
P
G
A
H
E
L
S
P
G
Q
S
S
A
F
Site 5
S74
H
E
L
S
P
G
Q
S
S
A
F
T
S
Q
G
Site 6
S75
E
L
S
P
G
Q
S
S
A
F
T
S
Q
G
P
Site 7
T78
P
G
Q
S
S
A
F
T
S
Q
G
P
G
A
Y
Site 8
S79
G
Q
S
S
A
F
T
S
Q
G
P
G
A
Y
P
Site 9
S107
P
H
A
A
H
V
G
S
Y
S
G
P
P
F
N
Site 10
Y108
H
A
A
H
V
G
S
Y
S
G
P
P
F
N
S
Site 11
S109
A
A
H
V
G
S
Y
S
G
P
P
F
N
S
T
Site 12
S115
Y
S
G
P
P
F
N
S
T
R
D
F
L
F
R
Site 13
S129
R
S
R
G
F
G
D
S
A
P
G
G
G
Q
H
Site 14
S151
G
G
L
H
H
A
H
S
D
A
Q
G
H
L
L
Site 15
S171
E
Q
H
G
P
H
G
S
Q
N
V
L
N
G
Q
Site 16
S199
E
Q
Y
R
Q
V
A
S
P
R
T
D
P
Y
S
Site 17
T202
R
Q
V
A
S
P
R
T
D
P
Y
S
A
A
Q
Site 18
Y205
A
S
P
R
T
D
P
Y
S
A
A
Q
L
H
N
Site 19
S206
S
P
R
T
D
P
Y
S
A
A
Q
L
H
N
Q
Site 20
S267
W
I
D
P
E
Q
L
S
N
P
K
K
S
C
N
Site 21
S272
Q
L
S
N
P
K
K
S
C
N
K
T
F
S
T
Site 22
T276
P
K
K
S
C
N
K
T
F
S
T
M
H
E
L
Site 23
S288
H
E
L
V
T
H
V
S
V
E
H
V
G
G
P
Site 24
Y318
G
K
P
F
K
A
K
Y
K
L
V
N
H
I
R
Site 25
T328
V
N
H
I
R
V
H
T
G
E
K
P
F
P
C
Site 26
S347
C
G
K
V
F
A
R
S
E
N
L
K
I
H
K
Site 27
T356
N
L
K
I
H
K
R
T
H
T
G
E
K
P
F
Site 28
T358
K
I
H
K
R
T
H
T
G
E
K
P
F
Q
C
Site 29
S377
C
D
R
R
F
A
N
S
S
D
R
K
K
H
M
Site 30
S378
D
R
R
F
A
N
S
S
D
R
K
K
H
M
H
Site 31
Y393
V
H
T
S
D
K
P
Y
L
C
K
M
C
D
K
Site 32
Y402
C
K
M
C
D
K
S
Y
T
H
P
S
S
L
R
Site 33
T403
K
M
C
D
K
S
Y
T
H
P
S
S
L
R
K
Site 34
S406
D
K
S
Y
T
H
P
S
S
L
R
K
H
M
K
Site 35
S407
K
S
Y
T
H
P
S
S
L
R
K
H
M
K
V
Site 36
S417
K
H
M
K
V
H
E
S
S
P
Q
G
S
E
S
Site 37
S418
H
M
K
V
H
E
S
S
P
Q
G
S
E
S
S
Site 38
S422
H
E
S
S
P
Q
G
S
E
S
S
P
A
A
S
Site 39
S424
S
S
P
Q
G
S
E
S
S
P
A
A
S
S
G
Site 40
S425
S
P
Q
G
S
E
S
S
P
A
A
S
S
G
Y
Site 41
S429
S
E
S
S
P
A
A
S
S
G
Y
E
S
S
T
Site 42
S430
E
S
S
P
A
A
S
S
G
Y
E
S
S
T
P
Site 43
Y432
S
P
A
A
S
S
G
Y
E
S
S
T
P
P
G
Site 44
S434
A
A
S
S
G
Y
E
S
S
T
P
P
G
L
V
Site 45
S435
A
S
S
G
Y
E
S
S
T
P
P
G
L
V
S
Site 46
T436
S
S
G
Y
E
S
S
T
P
P
G
L
V
S
P
Site 47
S442
S
T
P
P
G
L
V
S
P
S
A
E
P
Q
S
Site 48
S444
P
P
G
L
V
S
P
S
A
E
P
Q
S
S
S
Site 49
S449
S
P
S
A
E
P
Q
S
S
S
N
L
S
P
A
Site 50
S450
P
S
A
E
P
Q
S
S
S
N
L
S
P
A
A
Site 51
S451
S
A
E
P
Q
S
S
S
N
L
S
P
A
A
A
Site 52
S454
P
Q
S
S
S
N
L
S
P
A
A
A
A
A
A
Site 53
S480
A
V
H
R
G
G
G
S
G
S
G
G
A
G
G
Site 54
S482
H
R
G
G
G
S
G
S
G
G
A
G
G
G
S
Site 55
S489
S
G
G
A
G
G
G
S
G
G
G
S
G
S
G
Site 56
S493
G
G
G
S
G
G
G
S
G
S
G
G
G
G
G
Site 57
S495
G
S
G
G
G
S
G
S
G
G
G
G
G
G
A
Site 58
S509
A
G
G
G
G
G
G
S
S
G
G
G
S
G
T
Site 59
S510
G
G
G
G
G
G
S
S
G
G
G
S
G
T
A
Site 60
S514
G
G
S
S
G
G
G
S
G
T
A
G
G
H
S
Site 61
T516
S
S
G
G
G
S
G
T
A
G
G
H
S
G
L
Site 62
S521
S
G
T
A
G
G
H
S
G
L
S
S
N
F
N
Site 63
S524
A
G
G
H
S
G
L
S
S
N
F
N
E
W
Y
Site 64
S525
G
G
H
S
G
L
S
S
N
F
N
E
W
Y
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation