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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HRAS
Full Name:
GTPase HRas
Alias:
C-H-ras; HRAS1; RasH; Transforming protein p21; Transforming protein p21/H-Ras-1; V-Ha-ras Harvey rat sarcoma viral oncogene; V-Ha-ras Harvey rat sarcoma viral oncogene homolog
Type:
G protein; G protein, monomeric (non-Rab)
Mass (Da):
21298
Number AA:
189
UniProt ID:
P01112
International Prot ID:
IPI00000006
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0031225
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0008022
PhosphoSite+
KinaseNET
Biological Process:
GO:0007265
GO:0007166
GO:0006935
Phosida
TranscriptoNet
STRING
Kinexus Products
GTPase HRas (T58-Y64, human) peptide - Powder PE-01BFV95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01BFV95#GTPase HRas (T58-Y64, human) peptide - Powder PE-01BFZ90#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01BFZ90
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y32
Q
N
H
F
V
D
E
Y
D
P
T
I
E
D
S
Site 2
T35
F
V
D
E
Y
D
P
T
I
E
D
S
Y
R
K
Site 3
S39
Y
D
P
T
I
E
D
S
Y
R
K
Q
V
V
I
Site 4
Y40
D
P
T
I
E
D
S
Y
R
K
Q
V
V
I
D
Site 5
T58
C
L
L
D
I
L
D
T
A
G
Q
E
E
Y
S
Site 6
Y64
D
T
A
G
Q
E
E
Y
S
A
M
R
D
Q
Y
Site 7
Y71
Y
S
A
M
R
D
Q
Y
M
R
T
G
E
G
F
Site 8
T74
M
R
D
Q
Y
M
R
T
G
E
G
F
L
C
V
Site 9
Y96
S
F
E
D
I
H
Q
Y
R
E
Q
I
K
R
V
Site 10
S106
Q
I
K
R
V
K
D
S
D
D
V
P
M
V
L
Site 11
S136
Q
A
Q
D
L
A
R
S
Y
G
I
P
Y
I
E
Site 12
Y137
A
Q
D
L
A
R
S
Y
G
I
P
Y
I
E
T
Site 13
Y141
A
R
S
Y
G
I
P
Y
I
E
T
S
A
K
T
Site 14
T144
Y
G
I
P
Y
I
E
T
S
A
K
T
R
Q
G
Site 15
S145
G
I
P
Y
I
E
T
S
A
K
T
R
Q
G
V
Site 16
T148
Y
I
E
T
S
A
K
T
R
Q
G
V
E
D
A
Site 17
Y157
Q
G
V
E
D
A
F
Y
T
L
V
R
E
I
R
Site 18
T158
G
V
E
D
A
F
Y
T
L
V
R
E
I
R
Q
Site 19
S177
K
L
N
P
P
D
E
S
G
P
G
C
M
S
C
Site 20
S183
E
S
G
P
G
C
M
S
C
K
C
V
L
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation