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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RPN1
Full Name:
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
Alias:
Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 67 kDa subunit; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit; OST1; RIB1; Ribophorin I; Ribophorin-1; RPN-I
Type:
EC 2.4.1.119; Glycan Metabolism - N-glycan biosynthesis; Transferase
Mass (Da):
68551
Number AA:
607
UniProt ID:
P04843
International Prot ID:
IPI00025874
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0005789
GO:0008250
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004576
GO:0004579
PhosphoSite+
KinaseNET
Biological Process:
GO:0006464
GO:0006486
GO:0006487
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
T
W
A
P
A
P
G
S
A
S
S
E
A
P
P
Site 2
S26
P
A
P
G
S
A
S
S
E
A
P
P
L
I
N
Site 3
T39
I
N
E
D
V
K
R
T
V
D
L
S
S
H
L
Site 4
S43
V
K
R
T
V
D
L
S
S
H
L
A
K
V
T
Site 5
S44
K
R
T
V
D
L
S
S
H
L
A
K
V
T
A
Site 6
S62
L
A
H
L
G
G
G
S
T
S
R
A
T
S
F
Site 7
T63
A
H
L
G
G
G
S
T
S
R
A
T
S
F
L
Site 8
T67
G
G
S
T
S
R
A
T
S
F
L
L
A
L
E
Site 9
S68
G
S
T
S
R
A
T
S
F
L
L
A
L
E
P
Site 10
T103
N
N
L
E
V
R
E
T
K
I
K
G
K
S
G
Site 11
S109
E
T
K
I
K
G
K
S
G
R
F
F
T
V
K
Site 12
Y142
Y
T
H
V
L
H
P
Y
P
T
Q
I
T
Q
S
Site 13
Y161
V
V
F
E
G
N
H
Y
F
Y
S
P
Y
P
T
Site 14
S164
E
G
N
H
Y
F
Y
S
P
Y
P
T
K
T
Q
Site 15
Y166
N
H
Y
F
Y
S
P
Y
P
T
K
T
Q
T
M
Site 16
T168
Y
F
Y
S
P
Y
P
T
K
T
Q
T
M
R
V
Site 17
T170
Y
S
P
Y
P
T
K
T
Q
T
M
R
V
K
L
Site 18
T172
P
Y
P
T
K
T
Q
T
M
R
V
K
L
A
S
Site 19
S179
T
M
R
V
K
L
A
S
R
N
V
E
S
Y
T
Site 20
Y185
A
S
R
N
V
E
S
Y
T
K
L
G
N
P
T
Site 21
Y200
R
S
E
D
L
L
D
Y
G
P
F
R
D
V
P
Site 22
Y209
P
F
R
D
V
P
A
Y
S
Q
D
T
F
K
V
Site 23
S210
F
R
D
V
P
A
Y
S
Q
D
T
F
K
V
H
Site 24
T213
V
P
A
Y
S
Q
D
T
F
K
V
H
Y
E
N
Site 25
Y218
Q
D
T
F
K
V
H
Y
E
N
N
S
P
F
L
Site 26
S222
K
V
H
Y
E
N
N
S
P
F
L
T
I
T
S
Site 27
T226
E
N
N
S
P
F
L
T
I
T
S
M
T
R
V
Site 28
S262
A
V
L
K
G
P
F
S
R
Y
D
Y
Q
R
Q
Site 29
Y264
L
K
G
P
F
S
R
Y
D
Y
Q
R
Q
P
D
Site 30
Y266
G
P
F
S
R
Y
D
Y
Q
R
Q
P
D
S
G
Site 31
S272
D
Y
Q
R
Q
P
D
S
G
I
S
S
I
R
S
Site 32
S275
R
Q
P
D
S
G
I
S
S
I
R
S
F
K
T
Site 33
S276
Q
P
D
S
G
I
S
S
I
R
S
F
K
T
I
Site 34
Y292
P
A
A
A
Q
D
V
Y
Y
R
D
E
I
G
N
Site 35
Y293
A
A
A
Q
D
V
Y
Y
R
D
E
I
G
N
V
Site 36
Y330
F
G
G
W
K
T
H
Y
I
V
G
Y
N
L
P
Site 37
Y334
K
T
H
Y
I
V
G
Y
N
L
P
S
Y
E
Y
Site 38
Y339
V
G
Y
N
L
P
S
Y
E
Y
L
Y
N
L
G
Site 39
Y341
Y
N
L
P
S
Y
E
Y
L
Y
N
L
G
D
Q
Site 40
Y343
L
P
S
Y
E
Y
L
Y
N
L
G
D
Q
Y
A
Site 41
Y349
L
Y
N
L
G
D
Q
Y
A
L
K
M
R
F
V
Site 42
S385
A
K
N
I
E
I
D
S
P
Y
E
I
S
R
A
Site 43
Y387
N
I
E
I
D
S
P
Y
E
I
S
R
A
P
D
Site 44
S390
I
D
S
P
Y
E
I
S
R
A
P
D
E
L
H
Site 45
T399
A
P
D
E
L
H
Y
T
Y
L
D
T
F
G
R
Site 46
Y400
P
D
E
L
H
Y
T
Y
L
D
T
F
G
R
P
Site 47
T464
V
R
L
D
F
S
I
T
K
D
P
A
A
E
A
Site 48
T499
L
Y
R
H
F
D
E
T
V
N
R
Y
K
Q
S
Site 49
S510
Y
K
Q
S
R
D
I
S
T
L
N
S
G
K
K
Site 50
T511
K
Q
S
R
D
I
S
T
L
N
S
G
K
K
S
Site 51
S514
R
D
I
S
T
L
N
S
G
K
K
S
L
E
T
Site 52
S518
T
L
N
S
G
K
K
S
L
E
T
E
H
K
A
Site 53
T539
L
L
Q
S
R
L
K
T
E
G
S
D
L
C
D
Site 54
S542
S
R
L
K
T
E
G
S
D
L
C
D
R
V
S
Site 55
S549
S
D
L
C
D
R
V
S
E
M
Q
K
L
D
A
Site 56
T581
A
G
K
L
K
K
D
T
Y
I
E
N
E
K
L
Site 57
Y582
G
K
L
K
K
D
T
Y
I
E
N
E
K
L
I
Site 58
S590
I
E
N
E
K
L
I
S
G
K
R
Q
E
L
V
Site 59
T598
G
K
R
Q
E
L
V
T
K
I
D
H
I
L
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation