PhosphoNET

           
Protein Info 
   
Short Name:  ITGB3
Full Name:  Integrin beta-3
Alias:  Platelet membrane glycoprotein IIIa
Type:  Adhesion protein
Mass (Da):  87058
Number AA:  788
UniProt ID:  P05106
International Prot ID:  IPI00303283
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0008305  GO:0031092   Uniprot OncoNet
Molecular Function:  GO:0042802  GO:0004872   PhosphoSite+ KinaseNET
Biological Process:  GO:0007596  GO:0007160  GO:0007229 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T208NPCYDMKTTCLPMFG
Site 2T227LTLTDQVTRFNEEVK
Site 3S439CPQEKEKSFTIKPVG
Site 4T441QEKEKSFTIKPVGFK
Site 5Y660DENTCNRYCRDEIES
Site 6T767RARAKWDTANNPLYK
Site 7Y773DTANNPLYKEATSTF
Site 8T777NPLYKEATSTFTNIT
Site 9S778PLYKEATSTFTNITY
Site 10T779LYKEATSTFTNITYR
Site 11T784TSTFTNITYRGT___
Site 12Y785STFTNITYRGT____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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