PhosphoNET

           
Protein Info 
   
Short Name:  ADRB1
Full Name:  Beta-1 adrenergic receptor
Alias:  ADRB1R; B1AR; Beta-1 adrenoceptor; Beta-1 adrenoreceptor
Type:  Receptor, G protein-coupled
Mass (Da):  51323
Number AA:  477
UniProt ID:  P08588
International Prot ID:  IPI00029278
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005887     Uniprot OncoNet
Molecular Function:  GO:0004940  GO:0005515   PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S17ASEPGNLSSAAPLPD
Site 2S18SEPGNLSSAAPLPDG
Site 3S47ASLLPPASESPEPLS
Site 4S49LLPPASESPEPLSQQ
Site 5S54SESPEPLSQQWTAGM
Site 6Y157CVIALDRYLAITSPF
Site 7T161LDRYLAITSPFRYQS
Site 8S162DRYLAITSPFRYQSL
Site 9Y166AITSPFRYQSLLTRA
Site 10S168TSPFRYQSLLTRARA
Site 11Y210SDEARRCYNDPKCCD
Site 12S260KQVKKIDSCERRFLG
Site 13S274GGPARPPSPSPSPVP
Site 14S276PARPPSPSPSPVPAP
Site 15S278RPPSPSPSPVPAPAP
Site 16S312RAGKRRPSRLVALRE
Site 17Y377SAFNPIIYCRSPDFR
Site 18S380NPIIYCRSPDFRKAF
Site 19T404AARRRHATHGDRPRA
Site 20S412HGDRPRASGCLARPG
Site 21S423ARPGPPPSPGAASDD
Site 22S428PPSPGAASDDDDDDV
Site 23T439DDDVVGATPPARLLE
Site 24S459NGGAAADSDSSLDEP
Site 25S461GAAADSDSSLDEPCR
Site 26S462AAADSDSSLDEPCRP
Site 27S473PCRPGFASESKV___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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