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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VIM
Full Name:
Vimentin
Alias:
VIME
Type:
Cytoskeletal protein - Microtubule dynamics
Mass (Da):
53652
Number AA:
466
UniProt ID:
P08670
International Prot ID:
IPI00418471
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005882
GO:0005882
Uniprot
OncoNet
Molecular Function:
GO:0008022
GO:0005200
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006928
GO:0044419
GO:0044419
Phosida
TranscriptoNet
STRING
Kinexus Products
Vimentin Y117 phosphosite-specific antibody AB-PN544#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN544#Vimentin (F114-K120, human) pY117 phosphopeptide - Powder PE-04AEW99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AEW99
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
S
T
R
S
V
S
S
S
S
Site 2
S5
_
_
_
M
S
T
R
S
V
S
S
S
S
Y
R
Site 3
S7
_
S
T
R
S
V
S
S
S
S
Y
R
R
M
F
Site 4
S8
S
T
R
S
V
S
S
S
S
Y
R
R
M
F
G
Site 5
S9
T
R
S
V
S
S
S
S
Y
R
R
M
F
G
G
Site 6
S10
T
R
S
V
S
S
S
S
Y
R
R
M
F
G
G
Site 7
Y11
R
S
V
S
S
S
S
Y
R
R
M
F
G
G
P
Site 8
T20
R
M
F
G
G
P
G
T
A
S
R
P
S
S
S
Site 9
S22
F
G
G
P
G
T
A
S
R
P
S
S
S
R
S
Site 10
S25
P
G
T
A
S
R
P
S
S
S
R
S
Y
V
T
Site 11
S26
G
T
A
S
R
P
S
S
S
R
S
Y
V
T
T
Site 12
S27
T
A
S
R
P
S
S
S
R
S
Y
V
T
T
S
Site 13
S29
S
R
P
S
S
S
R
S
Y
V
T
T
S
T
R
Site 14
Y30
R
P
S
S
S
R
S
Y
V
T
T
S
T
R
T
Site 15
T32
S
S
S
R
S
Y
V
T
T
S
T
R
T
Y
S
Site 16
T33
S
S
R
S
Y
V
T
T
S
T
R
T
Y
S
L
Site 17
S34
S
R
S
Y
V
T
T
S
T
R
T
Y
S
L
G
Site 18
T35
R
S
Y
V
T
T
S
T
R
T
Y
S
L
G
S
Site 19
T37
Y
V
T
T
S
T
R
T
Y
S
L
G
S
A
L
Site 20
Y38
V
T
T
S
T
R
T
Y
S
L
G
S
A
L
R
Site 21
S39
T
T
S
T
R
T
Y
S
L
G
S
A
L
R
P
Site 22
S42
T
R
T
Y
S
L
G
S
A
L
R
P
S
T
S
Site 23
S47
L
G
S
A
L
R
P
S
T
S
R
S
L
Y
A
Site 24
T48
G
S
A
L
R
P
S
T
S
R
S
L
Y
A
S
Site 25
S49
S
A
L
R
P
S
T
S
R
S
L
Y
A
S
S
Site 26
S51
L
R
P
S
T
S
R
S
L
Y
A
S
S
P
G
Site 27
Y53
P
S
T
S
R
S
L
Y
A
S
S
P
G
G
V
Site 28
S55
T
S
R
S
L
Y
A
S
S
P
G
G
V
Y
A
Site 29
S56
S
R
S
L
Y
A
S
S
P
G
G
V
Y
A
T
Site 30
Y61
A
S
S
P
G
G
V
Y
A
T
R
S
S
A
V
Site 31
T63
S
P
G
G
V
Y
A
T
R
S
S
A
V
R
L
Site 32
S65
G
G
V
Y
A
T
R
S
S
A
V
R
L
R
S
Site 33
S66
G
V
Y
A
T
R
S
S
A
V
R
L
R
S
S
Site 34
S72
S
S
A
V
R
L
R
S
S
V
P
G
V
R
L
Site 35
S73
S
A
V
R
L
R
S
S
V
P
G
V
R
L
L
Site 36
S83
G
V
R
L
L
Q
D
S
V
D
F
S
L
A
D
Site 37
S87
L
Q
D
S
V
D
F
S
L
A
D
A
I
N
T
Site 38
T99
I
N
T
E
F
K
N
T
R
T
N
E
K
V
E
Site 39
Y117
L
N
D
R
F
A
N
Y
I
D
K
V
R
F
L
Vimentin Y117 phosphosite-specific antibody AB-PN544#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN544#Vimentin (F114-K120, human) pY117 phosphopeptide - Powder PE-04AEW99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AEW99
Site 40
S144
Q
L
K
G
Q
G
K
S
R
L
G
D
L
Y
E
Site 41
Y150
K
S
R
L
G
D
L
Y
E
E
E
M
R
E
L
Site 42
T165
R
R
Q
V
D
Q
L
T
N
D
K
A
R
V
E
Site 43
T202
Q
R
E
E
A
E
N
T
L
Q
S
F
R
Q
D
Site 44
S205
E
A
E
N
T
L
Q
S
F
R
Q
D
V
D
N
Site 45
S214
R
Q
D
V
D
N
A
S
L
A
R
L
D
L
E
Site 46
S226
D
L
E
R
K
V
E
S
L
Q
E
E
I
A
F
Site 47
S261
V
Q
I
D
V
D
V
S
K
P
D
L
T
A
A
Site 48
T266
D
V
S
K
P
D
L
T
A
A
L
R
D
V
R
Site 49
Y276
L
R
D
V
R
Q
Q
Y
E
S
V
A
A
K
N
Site 50
S278
D
V
R
Q
Q
Y
E
S
V
A
A
K
N
L
Q
Site 51
Y291
L
Q
E
A
E
E
W
Y
K
S
K
F
A
D
L
Site 52
S293
E
A
E
E
W
Y
K
S
K
F
A
D
L
S
E
Site 53
S299
K
S
K
F
A
D
L
S
E
A
A
N
R
N
N
Site 54
S316
L
R
Q
A
K
Q
E
S
T
E
Y
R
R
Q
V
Site 55
T317
R
Q
A
K
Q
E
S
T
E
Y
R
R
Q
V
Q
Site 56
Y319
A
K
Q
E
S
T
E
Y
R
R
Q
V
Q
S
L
Site 57
S325
E
Y
R
R
Q
V
Q
S
L
T
C
E
V
D
A
Site 58
T327
R
R
Q
V
Q
S
L
T
C
E
V
D
A
L
K
Site 59
S339
A
L
K
G
T
N
E
S
L
E
R
Q
M
R
E
Site 60
Y358
F
A
V
E
A
A
N
Y
Q
D
T
I
G
R
L
Site 61
Y383
M
A
R
H
L
R
E
Y
Q
D
L
L
N
V
K
Site 62
Y400
L
D
I
E
I
A
T
Y
R
K
L
L
E
G
E
Site 63
S409
K
L
L
E
G
E
E
S
R
I
S
L
P
L
P
Site 64
S412
E
G
E
E
S
R
I
S
L
P
L
P
N
F
S
Site 65
S419
S
L
P
L
P
N
F
S
S
L
N
L
R
E
T
Site 66
S420
L
P
L
P
N
F
S
S
L
N
L
R
E
T
N
Site 67
T426
S
S
L
N
L
R
E
T
N
L
D
S
L
P
L
Site 68
S430
L
R
E
T
N
L
D
S
L
P
L
V
D
T
H
Site 69
T436
D
S
L
P
L
V
D
T
H
S
K
R
T
L
L
Site 70
S438
L
P
L
V
D
T
H
S
K
R
T
L
L
I
K
Site 71
T441
V
D
T
H
S
K
R
T
L
L
I
K
T
V
E
Site 72
T446
K
R
T
L
L
I
K
T
V
E
T
R
D
G
Q
Site 73
T458
G
Q
V
I
N
E
T
S
Q
H
H
D
D
L
E
Site 74
S459
G
Q
V
I
N
E
T
S
Q
H
H
D
D
L
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation