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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HMOX1
Full Name:
Heme oxygenase 1
Alias:
BK286B10; Heme oxygenase (Decycling) 1; Heme oxygenase (decycling) 1; HO; HO1; HO-1
Type:
EC 1.14.99.3; Oxidoreductase; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll
Mass (Da):
32819
Number AA:
288
UniProt ID:
P09601
International Prot ID:
IPI00215893
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0005615
GO:0005792
Uniprot
OncoNet
Molecular Function:
GO:0019899
GO:0020037
GO:0004392
PhosphoSite+
KinaseNET
Biological Process:
GO:0001525
GO:0006916
GO:0008219
Phosida
TranscriptoNet
STRING
Kinexus Products
Heme oxygenase 1 pan-specific antibody AB-NN052-2#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN052-2#Heme oxygenase 1 pan-specific antibody AB-NN052-3#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN052-3#Heme oxygenase 1 pan-specific antibody AB-NN052-4#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN052-4#Heme oxygenase 1 pan-specific antibody AB-NN052-5#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN052-5#Heme oxygenase 1 pan-specific antibody AB-NN052-6#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN052-6
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
E
R
P
Q
P
D
S
M
P
Q
D
L
S
E
Site 2
S14
D
S
M
P
Q
D
L
S
E
A
L
K
E
A
T
Site 3
S71
E
I
E
R
N
K
E
S
P
V
F
A
P
V
Y
Site 4
Y78
S
P
V
F
A
P
V
Y
F
P
E
E
L
H
R
Site 5
Y97
E
Q
D
L
A
F
W
Y
G
P
R
W
Q
E
V
Site 6
Y107
R
W
Q
E
V
I
P
Y
T
P
A
M
Q
R
Y
Site 7
Y114
Y
T
P
A
M
Q
R
Y
V
K
R
L
H
E
V
Site 8
T124
R
L
H
E
V
G
R
T
E
P
E
L
L
V
A
Site 9
Y137
V
A
H
A
Y
T
R
Y
L
G
D
L
S
G
G
Site 10
S142
T
R
Y
L
G
D
L
S
G
G
Q
V
L
K
K
Site 11
S159
Q
K
A
L
D
L
P
S
S
G
E
G
L
A
F
Site 12
Y182
A
T
K
F
K
Q
L
Y
R
S
R
M
N
S
L
Site 13
S184
K
F
K
Q
L
Y
R
S
R
M
N
S
L
E
M
Site 14
S188
L
Y
R
S
R
M
N
S
L
E
M
T
P
A
V
Site 15
T192
R
M
N
S
L
E
M
T
P
A
V
R
Q
R
V
Site 16
T225
Q
E
L
L
T
H
D
T
K
D
Q
S
P
S
R
Site 17
S229
T
H
D
T
K
D
Q
S
P
S
R
A
P
G
L
Site 18
S231
D
T
K
D
Q
S
P
S
R
A
P
G
L
R
Q
Site 19
S241
P
G
L
R
Q
R
A
S
N
K
V
Q
D
S
A
Site 20
T252
Q
D
S
A
P
V
E
T
P
R
G
K
P
P
L
Site 21
T261
R
G
K
P
P
L
N
T
R
S
Q
A
P
L
L
Site 22
S263
K
P
P
L
N
T
R
S
Q
A
P
L
L
R
W
Site 23
Y286
A
T
V
A
V
G
L
Y
A
M
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation