PhosphoNET

           
Protein Info 
   
Short Name:  PDGFRB
Full Name:  Beta-type platelet-derived growth factor receptor
Alias:  CD140b; EC 2.7.10.1; JTK12; Kinase PDGFR-beta; PDGFR; PDGFR1; PDGFRb; PDGFR-beta; PDGF-R-beta; PGFRB; Platelet-derived growth factor receptor, beta polypeptide
Type:  Receptor tyrosine kinase; EC 2.7.10.1; TK group; PDGFR family
Mass (Da):  123968
Number AA:  1106
UniProt ID:  P09619
International Prot ID:  IPI00015902
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005887     Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0004992  GO:0005019 PhosphoSite+ KinaseNET
Biological Process:  GO:0060326  GO:0018108  GO:0048008 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y562LWQKKPRYEIRWKVI
Site 2S571IRWKVIESVSSDGHE
Site 3S573WKVIESVSSDGHEYI
Site 4S574KVIESVSSDGHEYIY
Site 5Y579VSSDGHEYIYVDPMQ
Site 6Y581SDGHEYIYVDPMQLP
Site 7Y589VDPMQLPYDSTWELP
Site 8S591PMQLPYDSTWELPRD
Site 9T605DQLVLGRTLGSGAFG
Site 10T618FGQVVEATAHGLSHS
Site 11S623EATAHGLSHSQATMK
Site 12S625TAHGLSHSQATMKVA
Site 13S638VAVKMLKSTARSSEK
Site 14T639AVKMLKSTARSSEKQ
Site 15S643LKSTARSSEKQALMS
Site 16Y678CTKGGPIYIITEYCR
Site 17Y683PIYIITEYCRYGDLV
Site 18Y686IITEYCRYGDLVDYL
Site 19Y692RYGDLVDYLHRNKHT
Site 20T699YLHRNKHTFLQHHSD
Site 21S705HTFLQHHSDKRRPPS
Site 22S712SDKRRPPSAELYSNA
Site 23Y716RPPSAELYSNALPVG
Site 24S731LPLPSHVSLTGESDG
Site 25T733LPSHVSLTGESDGGY
Site 26Y740TGESDGGYMDMSKDE
Site 27S744DGGYMDMSKDESVDY
Site 28S748MDMSKDESVDYVPML
Site 29Y751SKDESVDYVPMLDMK
Site 30Y763DMKGDVKYADIESSN
Site 31Y771ADIESSNYMAPYDNY
Site 32Y775SSNYMAPYDNYVPSA
Site 33Y778YMAPYDNYVPSAPER
Site 34S781PYDNYVPSAPERTCR
Site 35T786VPSAPERTCRATLIN
Site 36T790PERTCRATLINESPV
Site 37S795RATLINESPVLSYMD
Site 38S855ARDIMRDSNYISKGS
Site 39Y857DIMRDSNYISKGSTF
Site 40S859MRDSNYISKGSTFLP
Site 41T863NYISKGSTFLPLKWM
Site 42S878APESIFNSLYTTLSD
Site 43Y880ESIFNSLYTTLSDVW
Site 44Y904FTLGGTPYPELPMNE
Site 45Y914LPMNEQFYNAIKRGY
Site 46Y921YNAIKRGYRMAQPAH
Site 47S930MAQPAHASDEIYEIM
Site 48Y934AHASDEIYEIMQKCW
Site 49Y970GEGYKKKYQQVDEEF
Site 50S980VDEEFLRSDHPAILR
Site 51S988DHPAILRSQARLPGF
Site 52S1000PGFHGLRSPLDTSSV
Site 53T1004GLRSPLDTSSVLYTA
Site 54S1006RSPLDTSSVLYTAVQ
Site 55Y1009LDTSSVLYTAVQPNE
Site 56T1010DTSSVLYTAVQPNEG
Site 57Y1021PNEGDNDYIIPLPDP
Site 58S1041DEGPLEGSPSLASST
Site 59S1043GPLEGSPSLASSTLN
Site 60S1047GSPSLASSTLNEVNT
Site 61T1048SPSLASSTLNEVNTS
Site 62T1054STLNEVNTSSTISCD
Site 63S1055TLNEVNTSSTISCDS
Site 64S1056LNEVNTSSTISCDSP
Site 65S1059VNTSSTISCDSPLEP
Site 66S1062SSTISCDSPLEPQDE
Site 67S1092ELEQLPDSGCPAPRA
Site 68S1104PRAEAEDSFL_____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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