PhosphoNET

           
Protein Info 
   
Short Name:  HNRNPA1
Full Name:  Heterogeneous nuclear ribonucleoprotein A1
Alias:  FLI-2; HDP-1; Helix-destabilizing protein; HnRNP core protein A1; HnRNPA1; HnRNP-A1; HNRPA1; ROA1; Single-strand binding protein; TIS; Topoisomerase-inhibitor suppressed
Type:  RNA binding protein
Mass (Da):  38747
Number AA:  372
UniProt ID:  P09651
International Prot ID:  IPI00465365
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0030530  GO:0005730 Uniprot OncoNet
Molecular Function:  GO:0000166  GO:0005515  GO:0003697 PhosphoSite+ KinaseNET
Biological Process:  GO:0006405  GO:0051028  GO:0051170 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S2______MSKSESPKE
Site 2S4____MSKSESPKEPE
Site 3S6__MSKSESPKEPEQL
Site 4S22KLFIGGLSFETTDES
Site 5T25IGGLSFETTDESLRS
Site 6T26GGLSFETTDESLRSH
Site 7S29SFETTDESLRSHFEQ
Site 8S32TTDESLRSHFEQWGT
Site 9T51VVMRDPNTKRSRGFG
Site 10T64FGFVTYATVEEVDAA
Site 11S91VEPKRAVSREDSQRP
Site 12S95RAVSREDSQRPGAHL
Site 13T103QRPGAHLTVKKIFVG
Site 14T116VGGIKEDTEEHHLRD
Site 15Y124EEHHLRDYFEQYGKI
Site 16T138IEVIEIMTDRGSGKK
Site 17S142EIMTDRGSGKKRGFA
Site 18T152KRGFAFVTFDDHDSV
Site 19S158VTFDDHDSVDKIVIQ
Site 20Y167DKIVIQKYHTVNGHN
Site 21T169IVIQKYHTVNGHNCE
Site 22S182CEVRKALSKQEMASA
Site 23S188LSKQEMASASSSQRG
Site 24S190KQEMASASSSQRGRS
Site 25S191QEMASASSSQRGRSG
Site 26S192EMASASSSQRGRSGS
Site 27S197SSSQRGRSGSGNFGG
Site 28S199SQRGRSGSGNFGGGR
Site 29S223FGRGGNFSGRGGFGG
Site 30S231GRGGFGGSRGGGGYG
Site 31Y237GSRGGGGYGGSGDGY
Site 32S240GGGGYGGSGDGYNGF
Site 33Y244YGGSGDGYNGFGNDG
Site 34Y253GFGNDGGYGGGGPGY
Site 35Y260YGGGGPGYSGGSRGY
Site 36S261GGGGPGYSGGSRGYG
Site 37S264GPGYSGGSRGYGSGG
Site 38Y267YSGGSRGYGSGGQGY
Site 39S269GGSRGYGSGGQGYGN
Site 40Y274YGSGGQGYGNQGSGY
Site 41S279QGYGNQGSGYGGSGS
Site 42Y281YGNQGSGYGGSGSYD
Site 43S284QGSGYGGSGSYDSYN
Site 44S286SGYGGSGSYDSYNNG
Site 45Y287GYGGSGSYDSYNNGG
Site 46S289GGSGSYDSYNNGGGR
Site 47Y290GSGSYDSYNNGGGRG
Site 48S302GRGFGGGSGSNFGGG
Site 49S304GFGGGSGSNFGGGGS
Site 50S311SNFGGGGSYNDFGNY
Site 51Y312NFGGGGSYNDFGNYN
Site 52Y318SYNDFGNYNNQSSNF
Site 53S323GNYNNQSSNFGPMKG
Site 54S337GGNFGGRSSGPYGGG
Site 55S338GNFGGRSSGPYGGGG
Site 56Y341GGRSSGPYGGGGQYF
Site 57Y347PYGGGGQYFAKPRNQ
Site 58Y357KPRNQGGYGGSSSSS
Site 59S360NQGGYGGSSSSSSYG
Site 60S361QGGYGGSSSSSSYGS
Site 61S362GGYGGSSSSSSYGSG
Site 62S363GYGGSSSSSSYGSGR
Site 63S364YGGSSSSSSYGSGRR
Site 64S365GGSSSSSSYGSGRRF
Site 65Y366GSSSSSSYGSGRRF_
Site 66S368SSSSSYGSGRRF___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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