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Updated November 2019
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Protein Info
Short Name:
MAP2
Full Name:
Microtubule-associated protein 2
Alias:
MAP 2; MAP-2; MAP2A; MAP2B; MAP2C; MTAP2
Type:
Cytoskeletal protein - Microtubule dynamics
Mass (Da):
199526
Number AA:
1827
UniProt ID:
P11137
International Prot ID:
IPI00003842
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005874
GO:0005875
Uniprot
OncoNet
Molecular Function:
GO:0005516
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0007026
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
H
W
T
S
A
P
L
T
E
A
S
A
H
S
H
Site 2
S23
S
A
P
L
T
E
A
S
A
H
S
H
P
P
E
Site 3
S44
A
G
E
G
L
V
R
S
A
N
G
F
P
Y
R
Site 4
Y50
R
S
A
N
G
F
P
Y
R
E
D
E
E
G
A
Site 5
S63
G
A
F
G
E
H
G
S
Q
G
T
Y
S
N
T
Site 6
T66
G
E
H
G
S
Q
G
T
Y
S
N
T
K
E
N
Site 7
Y67
E
H
G
S
Q
G
T
Y
S
N
T
K
E
N
G
Site 8
S68
H
G
S
Q
G
T
Y
S
N
T
K
E
N
G
I
Site 9
S81
G
I
N
G
E
L
T
S
A
D
R
E
T
A
E
Site 10
T86
L
T
S
A
D
R
E
T
A
E
E
V
S
A
R
Site 11
S91
R
E
T
A
E
E
V
S
A
R
I
V
Q
V
V
Site 12
T130
L
P
L
A
A
E
E
T
A
N
L
P
P
S
P
Site 13
S136
E
T
A
N
L
P
P
S
P
P
P
S
P
A
S
Site 14
S140
L
P
P
S
P
P
P
S
P
A
S
E
Q
T
V
Site 15
S143
S
P
P
P
S
P
A
S
E
Q
T
V
T
V
E
Site 16
T146
P
S
P
A
S
E
Q
T
V
T
V
E
E
D
L
Site 17
T148
P
A
S
E
Q
T
V
T
V
E
E
D
L
L
T
Site 18
T155
T
V
E
E
D
L
L
T
A
S
K
M
E
F
H
Site 19
S157
E
E
D
L
L
T
A
S
K
M
E
F
H
D
Q
Site 20
T168
F
H
D
Q
Q
E
L
T
P
S
T
A
E
P
S
Site 21
S170
D
Q
Q
E
L
T
P
S
T
A
E
P
S
D
Q
Site 22
T171
Q
Q
E
L
T
P
S
T
A
E
P
S
D
Q
K
Site 23
S182
S
D
Q
K
E
K
E
S
E
K
Q
S
K
P
G
Site 24
S186
E
K
E
S
E
K
Q
S
K
P
G
E
D
L
K
Site 25
S199
L
K
H
A
A
L
V
S
Q
P
E
T
T
K
T
Site 26
T203
A
L
V
S
Q
P
E
T
T
K
T
Y
P
D
K
Site 27
T206
S
Q
P
E
T
T
K
T
Y
P
D
K
K
D
M
Site 28
Y207
Q
P
E
T
T
K
T
Y
P
D
K
K
D
M
Q
Site 29
S233
F
G
H
T
L
V
A
S
L
E
D
M
K
Q
K
Site 30
S244
M
K
Q
K
T
E
P
S
L
V
V
P
G
I
D
Site 31
T258
D
L
P
K
E
P
P
T
P
K
E
Q
K
D
W
Site 32
S285
W
G
L
V
A
P
I
S
P
G
P
L
T
P
M
Site 33
T290
P
I
S
P
G
P
L
T
P
M
R
E
K
D
V
Site 34
S311
W
E
G
K
Q
F
D
S
P
M
P
S
P
F
Q
Site 35
S315
Q
F
D
S
P
M
P
S
P
F
Q
G
G
S
F
Site 36
S321
P
S
P
F
Q
G
G
S
F
T
L
P
L
D
V
Site 37
T323
P
F
Q
G
G
S
F
T
L
P
L
D
V
M
K
Site 38
T335
V
M
K
N
E
I
V
T
E
T
S
P
F
A
P
Site 39
S352
L
Q
P
D
D
K
K
S
L
Q
Q
T
S
G
P
Site 40
T356
D
K
K
S
L
Q
Q
T
S
G
P
A
T
A
K
Site 41
T361
Q
Q
T
S
G
P
A
T
A
K
D
S
F
K
I
Site 42
S365
G
P
A
T
A
K
D
S
F
K
I
E
E
P
H
Site 43
S385
K
M
A
E
A
P
P
S
E
A
M
T
L
P
K
Site 44
T389
A
P
P
S
E
A
M
T
L
P
K
D
A
H
I
Site 45
T425
E
T
V
Q
Q
R
D
T
F
T
P
S
G
Q
E
Site 46
T427
V
Q
Q
R
D
T
F
T
P
S
G
Q
E
P
I
Site 47
T436
S
G
Q
E
P
I
L
T
E
K
E
T
E
L
K
Site 48
T449
L
K
L
E
E
K
T
T
I
S
D
K
E
A
V
Site 49
S451
L
E
E
K
T
T
I
S
D
K
E
A
V
P
K
Site 50
S460
K
E
A
V
P
K
E
S
K
P
P
K
P
A
D
Site 51
S476
E
I
G
I
I
Q
T
S
T
E
H
T
F
S
E
Site 52
T477
I
G
I
I
Q
T
S
T
E
H
T
F
S
E
Q
Site 53
T480
I
Q
T
S
T
E
H
T
F
S
E
Q
K
D
Q
Site 54
S482
T
S
T
E
H
T
F
S
E
Q
K
D
Q
E
P
Site 55
S498
T
D
M
L
K
Q
D
S
F
P
V
S
L
E
Q
Site 56
S502
K
Q
D
S
F
P
V
S
L
E
Q
A
V
T
D
Site 57
T508
V
S
L
E
Q
A
V
T
D
S
A
M
T
S
K
Site 58
S510
L
E
Q
A
V
T
D
S
A
M
T
S
K
T
L
Site 59
S514
V
T
D
S
A
M
T
S
K
T
L
E
K
A
M
Site 60
T516
D
S
A
M
T
S
K
T
L
E
K
A
M
T
E
Site 61
T522
K
T
L
E
K
A
M
T
E
P
S
A
L
I
E
Site 62
S525
E
K
A
M
T
E
P
S
A
L
I
E
K
S
S
Site 63
S531
P
S
A
L
I
E
K
S
S
I
Q
E
L
F
E
Site 64
S532
S
A
L
I
E
K
S
S
I
Q
E
L
F
E
M
Site 65
Y563
A
E
L
D
M
P
F
Y
E
D
K
S
G
M
S
Site 66
Y572
D
K
S
G
M
S
K
Y
F
E
T
S
A
L
K
Site 67
S585
L
K
E
E
A
T
K
S
I
E
P
G
S
D
Y
Site 68
S590
T
K
S
I
E
P
G
S
D
Y
Y
E
L
S
D
Site 69
Y592
S
I
E
P
G
S
D
Y
Y
E
L
S
D
T
R
Site 70
Y593
I
E
P
G
S
D
Y
Y
E
L
S
D
T
R
E
Site 71
S596
G
S
D
Y
Y
E
L
S
D
T
R
E
S
V
H
Site 72
T598
D
Y
Y
E
L
S
D
T
R
E
S
V
H
E
S
Site 73
S601
E
L
S
D
T
R
E
S
V
H
E
S
I
D
T
Site 74
S605
T
R
E
S
V
H
E
S
I
D
T
M
S
P
M
Site 75
T608
S
V
H
E
S
I
D
T
M
S
P
M
H
K
N
Site 76
S610
H
E
S
I
D
T
M
S
P
M
H
K
N
G
D
Site 77
T622
N
G
D
K
E
F
Q
T
G
K
E
S
Q
P
S
Site 78
S626
E
F
Q
T
G
K
E
S
Q
P
S
P
P
A
Q
Site 79
S629
T
G
K
E
S
Q
P
S
P
P
A
Q
E
A
G
Site 80
S638
P
A
Q
E
A
G
Y
S
T
L
A
Q
S
Y
P
Site 81
T639
A
Q
E
A
G
Y
S
T
L
A
Q
S
Y
P
S
Site 82
S643
G
Y
S
T
L
A
Q
S
Y
P
S
D
L
P
E
Site 83
Y644
Y
S
T
L
A
Q
S
Y
P
S
D
L
P
E
E
Site 84
S646
T
L
A
Q
S
Y
P
S
D
L
P
E
E
P
S
Site 85
S653
S
D
L
P
E
E
P
S
S
P
Q
E
R
M
F
Site 86
S654
D
L
P
E
E
P
S
S
P
Q
E
R
M
F
T
Site 87
T661
S
P
Q
E
R
M
F
T
I
D
P
K
V
Y
G
Site 88
T682
S
K
N
K
D
D
L
T
L
S
R
S
L
G
L
Site 89
S684
N
K
D
D
L
T
L
S
R
S
L
G
L
G
G
Site 90
S686
D
D
L
T
L
S
R
S
L
G
L
G
G
R
S
Site 91
S693
S
L
G
L
G
G
R
S
A
I
E
Q
R
S
M
Site 92
S699
R
S
A
I
E
Q
R
S
M
S
I
N
L
P
M
Site 93
S701
A
I
E
Q
R
S
M
S
I
N
L
P
M
S
C
Site 94
S725
F
G
R
G
H
D
L
S
P
L
A
S
D
I
L
Site 95
S729
H
D
L
S
P
L
A
S
D
I
L
T
N
T
S
Site 96
T733
P
L
A
S
D
I
L
T
N
T
S
G
S
M
D
Site 97
T735
A
S
D
I
L
T
N
T
S
G
S
M
D
E
G
Site 98
S736
S
D
I
L
T
N
T
S
G
S
M
D
E
G
D
Site 99
S738
I
L
T
N
T
S
G
S
M
D
E
G
D
D
Y
Site 100
Y745
S
M
D
E
G
D
D
Y
L
P
A
T
T
P
A
Site 101
T750
D
D
Y
L
P
A
T
T
P
A
L
E
K
A
P
Site 102
S785
E
S
T
Q
A
E
I
S
C
E
S
P
F
L
A
Site 103
S788
Q
A
E
I
S
C
E
S
P
F
L
A
K
D
F
Site 104
Y796
P
F
L
A
K
D
F
Y
K
N
G
T
V
M
A
Site 105
S817
L
D
L
A
G
T
R
S
R
L
A
S
V
S
A
Site 106
S821
G
T
R
S
R
L
A
S
V
S
A
D
A
E
V
Site 107
S823
R
S
R
L
A
S
V
S
A
D
A
E
V
A
R
Site 108
S833
A
E
V
A
R
R
K
S
V
P
S
E
T
V
V
Site 109
S836
A
R
R
K
S
V
P
S
E
T
V
V
E
D
S
Site 110
T838
R
K
S
V
P
S
E
T
V
V
E
D
S
R
T
Site 111
S843
S
E
T
V
V
E
D
S
R
T
G
L
P
P
V
Site 112
T845
T
V
V
E
D
S
R
T
G
L
P
P
V
T
D
Site 113
T851
R
T
G
L
P
P
V
T
D
E
N
H
V
I
V
Site 114
T860
E
N
H
V
I
V
K
T
D
S
Q
L
E
D
L
Site 115
S862
H
V
I
V
K
T
D
S
Q
L
E
D
L
G
Y
Site 116
Y869
S
Q
L
E
D
L
G
Y
C
V
F
N
K
Y
T
Site 117
Y875
G
Y
C
V
F
N
K
Y
T
V
P
L
P
S
P
Site 118
S881
K
Y
T
V
P
L
P
S
P
V
Q
D
S
E
N
Site 119
S886
L
P
S
P
V
Q
D
S
E
N
L
S
G
E
S
Site 120
S890
V
Q
D
S
E
N
L
S
G
E
S
G
T
F
Y
Site 121
T895
N
L
S
G
E
S
G
T
F
Y
E
G
T
D
D
Site 122
Y897
S
G
E
S
G
T
F
Y
E
G
T
D
D
K
V
Site 123
T900
S
G
T
F
Y
E
G
T
D
D
K
V
R
R
D
Site 124
T910
K
V
R
R
D
L
A
T
D
L
S
L
I
E
V
Site 125
S913
R
D
L
A
T
D
L
S
L
I
E
V
K
L
A
Site 126
S930
G
R
V
K
D
E
F
S
V
D
K
E
A
S
A
Site 127
S936
F
S
V
D
K
E
A
S
A
H
I
S
G
D
K
Site 128
S940
K
E
A
S
A
H
I
S
G
D
K
S
G
L
S
Site 129
S944
A
H
I
S
G
D
K
S
G
L
S
K
E
F
D
Site 130
T962
K
A
N
D
R
L
D
T
V
L
E
K
S
E
E
Site 131
S967
L
D
T
V
L
E
K
S
E
E
H
A
D
S
K
Site 132
S973
K
S
E
E
H
A
D
S
K
E
H
A
K
K
T
Site 133
T989
E
A
G
D
E
I
E
T
F
G
L
G
V
T
Y
Site 134
S1005
Q
A
L
A
K
D
L
S
I
P
T
D
A
S
S
Site 135
S1011
L
S
I
P
T
D
A
S
S
E
K
A
E
K
G
Site 136
S1012
S
I
P
T
D
A
S
S
E
K
A
E
K
G
L
Site 137
S1020
E
K
A
E
K
G
L
S
S
V
P
E
I
A
E
Site 138
S1021
K
A
E
K
G
L
S
S
V
P
E
I
A
E
V
Site 139
S1031
E
I
A
E
V
E
P
S
K
K
V
E
Q
G
L
Site 140
S1051
G
Q
L
D
V
K
I
S
D
F
G
Q
M
A
S
Site 141
S1058
S
D
F
G
Q
M
A
S
G
L
N
I
D
D
R
Site 142
T1068
N
I
D
D
R
R
A
T
E
L
K
L
E
A
T
Site 143
T1075
T
E
L
K
L
E
A
T
Q
D
M
T
P
S
S
Site 144
T1079
L
E
A
T
Q
D
M
T
P
S
S
K
A
P
Q
Site 145
S1082
T
Q
D
M
T
P
S
S
K
A
P
Q
E
A
D
Site 146
T1103
S
G
H
M
K
E
G
T
K
V
S
E
T
E
V
Site 147
S1106
M
K
E
G
T
K
V
S
E
T
E
V
K
E
K
Site 148
T1108
E
G
T
K
V
S
E
T
E
V
K
E
K
V
A
Site 149
S1130
E
A
V
D
K
E
E
S
Y
E
S
S
G
E
H
Site 150
Y1131
A
V
D
K
E
E
S
Y
E
S
S
G
E
H
E
Site 151
S1133
D
K
E
E
S
Y
E
S
S
G
E
H
E
S
L
Site 152
S1134
K
E
E
S
Y
E
S
S
G
E
H
E
S
L
T
Site 153
S1139
E
S
S
G
E
H
E
S
L
T
M
E
S
L
K
Site 154
T1141
S
G
E
H
E
S
L
T
M
E
S
L
K
A
D
Site 155
S1144
H
E
S
L
T
M
E
S
L
K
A
D
E
G
K
Site 156
T1154
A
D
E
G
K
K
E
T
S
P
E
S
S
L
I
Site 157
S1155
D
E
G
K
K
E
T
S
P
E
S
S
L
I
Q
Site 158
S1158
K
K
E
T
S
P
E
S
S
L
I
Q
D
E
I
Site 159
S1159
K
E
T
S
P
E
S
S
L
I
Q
D
E
I
A
Site 160
T1207
P
K
E
E
S
K
E
T
P
D
I
S
I
T
P
Site 161
S1211
S
K
E
T
P
D
I
S
I
T
P
S
D
V
A
Site 162
T1213
E
T
P
D
I
S
I
T
P
S
D
V
A
E
P
Site 163
S1215
P
D
I
S
I
T
P
S
D
V
A
E
P
L
H
Site 164
S1227
P
L
H
E
T
I
V
S
E
P
A
E
I
Q
S
Site 165
S1234
S
E
P
A
E
I
Q
S
E
E
E
E
I
E
A
Site 166
S1252
Y
D
K
L
L
F
R
S
D
T
L
Q
I
T
D
Site 167
T1254
K
L
L
F
R
S
D
T
L
Q
I
T
D
L
G
Site 168
T1258
R
S
D
T
L
Q
I
T
D
L
G
V
S
G
A
Site 169
S1263
Q
I
T
D
L
G
V
S
G
A
R
E
E
F
V
Site 170
T1272
A
R
E
E
F
V
E
T
C
P
S
E
H
K
G
Site 171
S1275
E
F
V
E
T
C
P
S
E
H
K
G
V
I
E
Site 172
S1283
E
H
K
G
V
I
E
S
V
V
T
I
E
D
D
Site 173
T1293
T
I
E
D
D
F
I
T
V
V
Q
T
T
T
D
Site 174
S1304
T
T
T
D
E
G
E
S
G
S
H
S
V
R
F
Site 175
S1306
T
D
E
G
E
S
G
S
H
S
V
R
F
A
A
Site 176
S1308
E
G
E
S
G
S
H
S
V
R
F
A
A
L
E
Site 177
S1324
P
E
V
E
R
R
P
S
P
H
D
E
E
E
F
Site 178
S1347
Q
A
E
P
K
D
G
S
P
E
A
P
A
S
P
Site 179
S1353
G
S
P
E
A
P
A
S
P
E
R
E
E
V
A
Site 180
S1362
E
R
E
E
V
A
L
S
E
Y
K
T
E
T
Y
Site 181
T1366
V
A
L
S
E
Y
K
T
E
T
Y
D
D
Y
K
Site 182
T1368
L
S
E
Y
K
T
E
T
Y
D
D
Y
K
D
E
Site 183
Y1369
S
E
Y
K
T
E
T
Y
D
D
Y
K
D
E
T
Site 184
Y1372
K
T
E
T
Y
D
D
Y
K
D
E
T
T
I
D
Site 185
T1377
D
D
Y
K
D
E
T
T
I
D
D
S
I
M
D
Site 186
S1381
D
E
T
T
I
D
D
S
I
M
D
A
D
S
L
Site 187
S1387
D
S
I
M
D
A
D
S
L
W
V
D
T
Q
D
Site 188
S1398
D
T
Q
D
D
D
R
S
I
M
T
E
Q
L
E
Site 189
T1406
I
M
T
E
Q
L
E
T
I
P
K
E
E
K
A
Site 190
S1420
A
E
K
E
A
R
R
S
S
L
E
K
H
R
K
Site 191
S1421
E
K
E
A
R
R
S
S
L
E
K
H
R
K
E
Site 192
T1433
R
K
E
K
P
F
K
T
G
R
G
R
I
S
T
Site 193
S1439
K
T
G
R
G
R
I
S
T
P
E
R
K
V
A
Site 194
T1440
T
G
R
G
R
I
S
T
P
E
R
K
V
A
K
Site 195
T1452
V
A
K
K
E
P
S
T
V
S
R
D
E
V
R
Site 196
Y1465
V
R
R
K
K
A
V
Y
K
K
A
E
L
A
K
Site 197
S1480
K
T
E
V
Q
A
H
S
P
S
R
K
F
I
L
Site 198
S1482
E
V
Q
A
H
S
P
S
R
K
F
I
L
K
P
Site 199
Y1493
I
L
K
P
A
I
K
Y
T
R
P
T
H
L
S
Site 200
T1497
A
I
K
Y
T
R
P
T
H
L
S
C
V
K
R
Site 201
S1500
Y
T
R
P
T
H
L
S
C
V
K
R
K
T
T
Site 202
T1506
L
S
C
V
K
R
K
T
T
A
A
G
G
E
S
Site 203
T1507
S
C
V
K
R
K
T
T
A
A
G
G
E
S
A
Site 204
S1528
K
Q
A
K
D
K
V
S
D
G
V
T
K
S
P
Site 205
T1532
D
K
V
S
D
G
V
T
K
S
P
E
K
R
S
Site 206
S1534
V
S
D
G
V
T
K
S
P
E
K
R
S
S
L
Site 207
S1539
T
K
S
P
E
K
R
S
S
L
P
R
P
S
S
Site 208
S1540
K
S
P
E
K
R
S
S
L
P
R
P
S
S
I
Site 209
S1545
R
S
S
L
P
R
P
S
S
I
L
P
P
R
R
Site 210
S1546
S
S
L
P
R
P
S
S
I
L
P
P
R
R
G
Site 211
S1555
L
P
P
R
R
G
V
S
G
D
R
D
E
N
S
Site 212
S1562
S
G
D
R
D
E
N
S
F
S
L
N
S
S
I
Site 213
S1564
D
R
D
E
N
S
F
S
L
N
S
S
I
S
S
Site 214
S1567
E
N
S
F
S
L
N
S
S
I
S
S
S
A
R
Site 215
S1568
N
S
F
S
L
N
S
S
I
S
S
S
A
R
R
Site 216
S1570
F
S
L
N
S
S
I
S
S
S
A
R
R
T
T
Site 217
S1571
S
L
N
S
S
I
S
S
S
A
R
R
T
T
R
Site 218
S1572
L
N
S
S
I
S
S
S
A
R
R
T
T
R
S
Site 219
T1576
I
S
S
S
A
R
R
T
T
R
S
E
P
I
R
Site 220
T1577
S
S
S
A
R
R
T
T
R
S
E
P
I
R
R
Site 221
S1579
S
A
R
R
T
T
R
S
E
P
I
R
R
A
G
Site 222
S1588
P
I
R
R
A
G
K
S
G
T
S
T
P
T
T
Site 223
T1590
R
R
A
G
K
S
G
T
S
T
P
T
T
P
G
Site 224
S1591
R
A
G
K
S
G
T
S
T
P
T
T
P
G
S
Site 225
T1592
A
G
K
S
G
T
S
T
P
T
T
P
G
S
T
Site 226
T1594
K
S
G
T
S
T
P
T
T
P
G
S
T
A
I
Site 227
T1595
S
G
T
S
T
P
T
T
P
G
S
T
A
I
T
Site 228
S1598
S
T
P
T
T
P
G
S
T
A
I
T
P
G
T
Site 229
T1599
T
P
T
T
P
G
S
T
A
I
T
P
G
T
P
Site 230
T1602
T
P
G
S
T
A
I
T
P
G
T
P
P
S
Y
Site 231
T1605
S
T
A
I
T
P
G
T
P
P
S
Y
S
S
R
Site 232
S1608
I
T
P
G
T
P
P
S
Y
S
S
R
T
P
G
Site 233
Y1609
T
P
G
T
P
P
S
Y
S
S
R
T
P
G
T
Site 234
S1610
P
G
T
P
P
S
Y
S
S
R
T
P
G
T
P
Site 235
S1611
G
T
P
P
S
Y
S
S
R
T
P
G
T
P
G
Site 236
T1613
P
P
S
Y
S
S
R
T
P
G
T
P
G
T
P
Site 237
T1616
Y
S
S
R
T
P
G
T
P
G
T
P
S
Y
P
Site 238
T1619
R
T
P
G
T
P
G
T
P
S
Y
P
R
T
P
Site 239
S1621
P
G
T
P
G
T
P
S
Y
P
R
T
P
H
T
Site 240
Y1622
G
T
P
G
T
P
S
Y
P
R
T
P
H
T
P
Site 241
T1625
G
T
P
S
Y
P
R
T
P
H
T
P
G
T
P
Site 242
T1628
S
Y
P
R
T
P
H
T
P
G
T
P
K
S
A
Site 243
T1631
R
T
P
H
T
P
G
T
P
K
S
A
I
L
V
Site 244
S1634
H
T
P
G
T
P
K
S
A
I
L
V
P
S
E
Site 245
T1649
K
K
V
A
I
I
R
T
P
P
K
S
P
A
T
Site 246
S1653
I
I
R
T
P
P
K
S
P
A
T
P
K
Q
L
Site 247
T1656
T
P
P
K
S
P
A
T
P
K
Q
L
R
L
I
Site 248
S1675
P
D
L
K
N
V
K
S
K
I
G
S
T
D
N
Site 249
S1679
N
V
K
S
K
I
G
S
T
D
N
I
K
Y
Q
Site 250
Y1685
G
S
T
D
N
I
K
Y
Q
P
K
G
G
Q
V
Site 251
S1702
V
T
K
K
I
D
L
S
H
V
T
S
K
C
G
Site 252
S1706
I
D
L
S
H
V
T
S
K
C
G
S
L
K
N
Site 253
S1710
H
V
T
S
K
C
G
S
L
K
N
I
R
H
R
Site 254
S1727
G
G
R
V
K
I
E
S
V
K
L
D
F
K
E
Site 255
S1742
K
A
Q
A
K
V
G
S
L
D
N
A
H
H
V
Site 256
S1759
G
G
N
V
K
I
D
S
Q
K
L
N
F
R
E
Site 257
T1780
D
H
G
A
E
I
I
T
Q
S
P
G
R
S
S
Site 258
S1782
G
A
E
I
I
T
Q
S
P
G
R
S
S
V
A
Site 259
S1786
I
T
Q
S
P
G
R
S
S
V
A
S
P
R
R
Site 260
S1787
T
Q
S
P
G
R
S
S
V
A
S
P
R
R
L
Site 261
S1790
P
G
R
S
S
V
A
S
P
R
R
L
S
N
V
Site 262
S1795
V
A
S
P
R
R
L
S
N
V
S
S
S
G
S
Site 263
S1798
P
R
R
L
S
N
V
S
S
S
G
S
I
N
L
Site 264
S1799
R
R
L
S
N
V
S
S
S
G
S
I
N
L
L
Site 265
S1800
R
L
S
N
V
S
S
S
G
S
I
N
L
L
E
Site 266
S1802
S
N
V
S
S
S
G
S
I
N
L
L
E
S
P
Site 267
S1808
G
S
I
N
L
L
E
S
P
Q
L
A
T
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation