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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSKH1
Full Name:
Serine/threonine-protein kinase H1
Alias:
Protein serine kinase H1
Type:
Mass (Da):
48035
Number AA:
424
UniProt ID:
P11801
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
V
K
K
V
E
P
F
S
G
T
K
S
D
V
Y
Site 2
S32
E
P
F
S
G
T
K
S
D
V
Y
K
H
F
I
Site 3
Y35
S
G
T
K
S
D
V
Y
K
H
F
I
T
E
V
Site 4
T40
D
V
Y
K
H
F
I
T
E
V
D
S
V
G
P
Site 5
S56
K
A
G
F
P
A
A
S
Q
Y
A
H
P
C
P
Site 6
Y58
G
F
P
A
A
S
Q
Y
A
H
P
C
P
G
P
Site 7
T71
G
P
P
T
A
G
H
T
E
P
P
S
E
P
P
Site 8
S75
A
G
H
T
E
P
P
S
E
P
P
R
R
A
R
Site 9
Y86
R
R
A
R
V
A
K
Y
R
A
K
F
D
P
R
Site 10
T95
A
K
F
D
P
R
V
T
A
K
Y
D
I
K
A
Site 11
Y98
D
P
R
V
T
A
K
Y
D
I
K
A
L
I
G
Site 12
S110
L
I
G
R
G
S
F
S
R
V
V
R
V
E
H
Site 13
T120
V
R
V
E
H
R
A
T
R
Q
P
Y
A
I
K
Site 14
Y124
H
R
A
T
R
Q
P
Y
A
I
K
M
I
E
T
Site 15
Y133
I
K
M
I
E
T
K
Y
R
E
G
R
E
V
C
Site 16
S142
E
G
R
E
V
C
E
S
E
L
R
V
L
R
R
Site 17
T164
Q
L
V
E
V
F
E
T
Q
E
R
V
Y
M
V
Site 18
Y169
F
E
T
Q
E
R
V
Y
M
V
M
E
L
A
T
Site 19
T176
Y
M
V
M
E
L
A
T
G
G
E
L
F
D
R
Site 20
S189
D
R
I
I
A
K
G
S
F
T
E
R
D
A
T
Site 21
T191
I
I
A
K
G
S
F
T
E
R
D
A
T
R
V
Site 22
T196
S
F
T
E
R
D
A
T
R
V
L
Q
M
V
L
Site 23
Y226
L
K
P
E
N
L
L
Y
Y
H
P
G
T
D
S
Site 24
Y227
K
P
E
N
L
L
Y
Y
H
P
G
T
D
S
K
Site 25
S244
I
T
D
F
G
L
A
S
A
R
K
K
G
D
D
Site 26
T256
G
D
D
C
L
M
K
T
T
C
G
T
P
E
Y
Site 27
T260
L
M
K
T
T
C
G
T
P
E
Y
I
A
P
E
Site 28
Y274
E
V
L
V
R
K
P
Y
T
N
S
V
D
M
W
Site 29
T275
V
L
V
R
K
P
Y
T
N
S
V
D
M
W
A
Site 30
Y306
D
D
N
R
T
R
L
Y
R
Q
I
L
R
G
K
Site 31
Y314
R
Q
I
L
R
G
K
Y
S
Y
S
G
E
P
W
Site 32
S315
Q
I
L
R
G
K
Y
S
Y
S
G
E
P
W
P
Site 33
S317
L
R
G
K
Y
S
Y
S
G
E
P
W
P
S
V
Site 34
S323
Y
S
G
E
P
W
P
S
V
S
N
L
A
K
D
Site 35
T345
V
D
P
G
A
R
M
T
A
L
Q
A
L
R
H
Site 36
S362
V
V
S
M
A
A
S
S
S
M
K
N
L
H
R
Site 37
S363
V
S
M
A
A
S
S
S
M
K
N
L
H
R
S
Site 38
S372
K
N
L
H
R
S
I
S
Q
N
L
L
K
R
A
Site 39
S380
Q
N
L
L
K
R
A
S
S
R
C
Q
S
T
K
Site 40
S381
N
L
L
K
R
A
S
S
R
C
Q
S
T
K
S
Site 41
S385
R
A
S
S
R
C
Q
S
T
K
S
A
Q
S
T
Site 42
T386
A
S
S
R
C
Q
S
T
K
S
A
Q
S
T
R
Site 43
S388
S
R
C
Q
S
T
K
S
A
Q
S
T
R
S
S
Site 44
S391
Q
S
T
K
S
A
Q
S
T
R
S
S
R
S
T
Site 45
T392
S
T
K
S
A
Q
S
T
R
S
S
R
S
T
R
Site 46
S394
K
S
A
Q
S
T
R
S
S
R
S
T
R
S
N
Site 47
S395
S
A
Q
S
T
R
S
S
R
S
T
R
S
N
K
Site 48
S397
Q
S
T
R
S
S
R
S
T
R
S
N
K
S
R
Site 49
T398
S
T
R
S
S
R
S
T
R
S
N
K
S
R
R
Site 50
S400
R
S
S
R
S
T
R
S
N
K
S
R
R
V
R
Site 51
S403
R
S
T
R
S
N
K
S
R
R
V
R
E
R
E
Site 52
Y418
L
R
E
L
N
L
R
Y
Q
Q
Q
Y
N
G
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation