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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UNG
Full Name:
Uracil-DNA glycosylase
Alias:
DGU; HIGM4; UDG; UNG1; UNG15; UNG2; Uracil-DNA glycosylase; Uracil-DNA glycosylase 1, uracil-DNA glycosylase 2
Type:
EC 3.2.2.-; Hydrolase
Mass (Da):
34645
Number AA:
313
UniProt ID:
P13051
International Prot ID:
IPI00011069
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004844
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006284
GO:0044419
GO:0006281
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
I
G
Q
K
T
L
Y
S
F
F
S
P
Site 2
Y8
M
I
G
Q
K
T
L
Y
S
F
F
S
P
S
P
Site 3
S9
I
G
Q
K
T
L
Y
S
F
F
S
P
S
P
A
Site 4
S12
K
T
L
Y
S
F
F
S
P
S
P
A
R
K
R
Site 5
S14
L
Y
S
F
F
S
P
S
P
A
R
K
R
H
A
Site 6
S23
A
R
K
R
H
A
P
S
P
E
P
A
V
Q
G
Site 7
T31
P
E
P
A
V
Q
G
T
G
V
A
G
V
P
E
Site 8
S40
V
A
G
V
P
E
E
S
G
D
A
A
A
I
P
Site 9
T60
A
G
Q
E
E
P
G
T
P
P
S
S
P
L
S
Site 10
S63
E
E
P
G
T
P
P
S
S
P
L
S
A
E
Q
Site 11
S64
E
P
G
T
P
P
S
S
P
L
S
A
E
Q
L
Site 12
S67
T
P
P
S
S
P
L
S
A
E
Q
L
D
R
I
Site 13
S97
V
P
V
G
F
G
E
S
W
K
K
H
L
S
G
Site 14
S103
E
S
W
K
K
H
L
S
G
E
F
G
K
P
Y
Site 15
Y125
V
A
E
E
R
K
H
Y
T
V
Y
P
P
P
H
Site 16
T126
A
E
E
R
K
H
Y
T
V
Y
P
P
P
H
Q
Site 17
Y128
E
R
K
H
Y
T
V
Y
P
P
P
H
Q
V
F
Site 18
Y156
V
I
L
G
Q
D
P
Y
H
G
P
N
Q
A
H
Site 19
S168
Q
A
H
G
L
C
F
S
V
Q
R
P
V
P
P
Site 20
S178
R
P
V
P
P
P
P
S
L
E
N
I
Y
K
E
Site 21
Y183
P
P
S
L
E
N
I
Y
K
E
L
S
T
D
I
Site 22
S187
E
N
I
Y
K
E
L
S
T
D
I
E
D
F
V
Site 23
S202
H
P
G
H
G
D
L
S
G
W
A
K
Q
G
V
Site 24
T275
K
R
H
H
V
L
Q
T
A
H
P
S
P
L
S
Site 25
S279
V
L
Q
T
A
H
P
S
P
L
S
V
Y
R
G
Site 26
S282
T
A
H
P
S
P
L
S
V
Y
R
G
F
F
G
Site 27
Y284
H
P
S
P
L
S
V
Y
R
G
F
F
G
C
R
Site 28
T296
G
C
R
H
F
S
K
T
N
E
L
L
Q
K
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation