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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
POU2F1
Full Name:
POU domain, class 2, transcription factor 1
Alias:
NF-A1; OCT1; Oct-1; Octamer-binding transcription factor 1; OTF1; OTF-1; PO21; PO2F1; POU class 2 homeobox 1
Type:
Transcription factor
Mass (Da):
76472
Number AA:
743
UniProt ID:
P14859
International Prot ID:
IPI00027828
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0045892
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
P
S
E
T
S
K
P
S
M
E
S
G
D
G
N
Site 2
T21
S
G
D
G
N
T
G
T
Q
T
N
G
L
D
F
Site 3
S67
S
L
Q
A
A
A
Q
S
L
N
V
Q
S
K
S
Site 4
S72
A
Q
S
L
N
V
Q
S
K
S
N
E
E
S
G
Site 5
S74
S
L
N
V
Q
S
K
S
N
E
E
S
G
D
S
Site 6
S78
Q
S
K
S
N
E
E
S
G
D
S
Q
Q
P
S
Site 7
S81
S
N
E
E
S
G
D
S
Q
Q
P
S
Q
P
S
Site 8
S85
S
G
D
S
Q
Q
P
S
Q
P
S
Q
Q
P
S
Site 9
S88
S
Q
Q
P
S
Q
P
S
Q
Q
P
S
V
Q
A
Site 10
S92
S
Q
P
S
Q
Q
P
S
V
Q
A
A
I
P
Q
Site 11
T100
V
Q
A
A
I
P
Q
T
Q
L
M
L
A
G
G
Site 12
T113
G
G
Q
I
T
G
L
T
L
T
P
A
Q
Q
Q
Site 13
S141
A
A
A
V
Q
Q
H
S
A
S
Q
Q
H
S
A
Site 14
S143
A
V
Q
Q
H
S
A
S
Q
Q
H
S
A
A
G
Site 15
S147
H
S
A
S
Q
Q
H
S
A
A
G
A
T
I
S
Site 16
T162
A
S
A
A
T
P
M
T
Q
I
P
L
S
Q
P
Site 17
S167
P
M
T
Q
I
P
L
S
Q
P
I
Q
I
A
Q
Site 18
S209
Q
P
A
Q
F
I
I
S
Q
T
P
Q
G
Q
Q
Site 19
T211
A
Q
F
I
I
S
Q
T
P
Q
G
Q
Q
G
L
Site 20
T226
L
Q
A
Q
N
L
L
T
Q
L
P
Q
Q
S
Q
Site 21
S232
L
T
Q
L
P
Q
Q
S
Q
A
N
L
L
Q
S
Site 22
S239
S
Q
A
N
L
L
Q
S
Q
P
S
I
T
L
T
Site 23
S242
N
L
L
Q
S
Q
P
S
I
T
L
T
S
Q
P
Site 24
T244
L
Q
S
Q
P
S
I
T
L
T
S
Q
P
A
T
Site 25
T246
S
Q
P
S
I
T
L
T
S
Q
P
A
T
P
T
Site 26
S247
Q
P
S
I
T
L
T
S
Q
P
A
T
P
T
R
Site 27
T251
T
L
T
S
Q
P
A
T
P
T
R
T
I
A
A
Site 28
T259
P
T
R
T
I
A
A
T
P
I
Q
T
L
P
Q
Site 29
T263
I
A
A
T
P
I
Q
T
L
P
Q
S
Q
S
T
Site 30
S267
P
I
Q
T
L
P
Q
S
Q
S
T
P
K
R
I
Site 31
S269
Q
T
L
P
Q
S
Q
S
T
P
K
R
I
D
T
Site 32
T270
T
L
P
Q
S
Q
S
T
P
K
R
I
D
T
P
Site 33
T276
S
T
P
K
R
I
D
T
P
S
L
E
E
P
S
Site 34
S278
P
K
R
I
D
T
P
S
L
E
E
P
S
D
L
Site 35
S283
T
P
S
L
E
E
P
S
D
L
E
E
L
E
Q
Site 36
T294
E
L
E
Q
F
A
K
T
F
K
Q
R
R
I
K
Site 37
Y317
G
L
A
M
G
K
L
Y
G
N
D
F
S
Q
T
Site 38
S322
K
L
Y
G
N
D
F
S
Q
T
T
I
S
R
F
Site 39
S335
R
F
E
A
L
N
L
S
F
K
N
M
C
K
L
Site 40
S357
L
N
D
A
E
N
L
S
S
D
S
S
L
S
S
Site 41
S358
N
D
A
E
N
L
S
S
D
S
S
L
S
S
P
Site 42
S360
A
E
N
L
S
S
D
S
S
L
S
S
P
S
A
Site 43
S361
E
N
L
S
S
D
S
S
L
S
S
P
S
A
L
Site 44
S363
L
S
S
D
S
S
L
S
S
P
S
A
L
N
S
Site 45
S364
S
S
D
S
S
L
S
S
P
S
A
L
N
S
P
Site 46
S366
D
S
S
L
S
S
P
S
A
L
N
S
P
G
I
Site 47
S370
S
S
P
S
A
L
N
S
P
G
I
E
G
L
S
Site 48
S377
S
P
G
I
E
G
L
S
R
R
R
K
K
R
T
Site 49
T384
S
R
R
R
K
K
R
T
S
I
E
T
N
I
R
Site 50
S385
R
R
R
K
K
R
T
S
I
E
T
N
I
R
V
Site 51
T388
K
K
R
T
S
I
E
T
N
I
R
V
A
L
E
Site 52
S397
I
R
V
A
L
E
K
S
F
L
E
N
Q
K
P
Site 53
S406
L
E
N
Q
K
P
T
S
E
E
I
T
M
I
A
Site 54
T410
K
P
T
S
E
E
I
T
M
I
A
D
Q
L
N
Site 55
S441
E
K
R
I
N
P
P
S
S
G
G
T
S
S
S
Site 56
S442
K
R
I
N
P
P
S
S
G
G
T
S
S
S
P
Site 57
T445
N
P
P
S
S
G
G
T
S
S
S
P
I
K
A
Site 58
S446
P
P
S
S
G
G
T
S
S
S
P
I
K
A
I
Site 59
S447
P
S
S
G
G
T
S
S
S
P
I
K
A
I
F
Site 60
S448
S
S
G
G
T
S
S
S
P
I
K
A
I
F
P
Site 61
T497
T
N
L
S
V
T
G
T
S
D
T
T
S
N
N
Site 62
S498
N
L
S
V
T
G
T
S
D
T
T
S
N
N
T
Site 63
T500
S
V
T
G
T
S
D
T
T
S
N
N
T
A
T
Site 64
S502
T
G
T
S
D
T
T
S
N
N
T
A
T
V
I
Site 65
T507
T
T
S
N
N
T
A
T
V
I
S
T
A
P
P
Site 66
S510
N
N
T
A
T
V
I
S
T
A
P
P
A
S
S
Site 67
S516
I
S
T
A
P
P
A
S
S
A
V
T
S
P
S
Site 68
S517
S
T
A
P
P
A
S
S
A
V
T
S
P
S
L
Site 69
T520
P
P
A
S
S
A
V
T
S
P
S
L
S
P
S
Site 70
S521
P
A
S
S
A
V
T
S
P
S
L
S
P
S
P
Site 71
S523
S
S
A
V
T
S
P
S
L
S
P
S
P
S
A
Site 72
S525
A
V
T
S
P
S
L
S
P
S
P
S
A
S
A
Site 73
S527
T
S
P
S
L
S
P
S
P
S
A
S
A
S
T
Site 74
S529
P
S
L
S
P
S
P
S
A
S
A
S
T
S
E
Site 75
S531
L
S
P
S
P
S
A
S
A
S
T
S
E
A
S
Site 76
S533
P
S
P
S
A
S
A
S
T
S
E
A
S
S
A
Site 77
T534
S
P
S
A
S
A
S
T
S
E
A
S
S
A
S
Site 78
S535
P
S
A
S
A
S
T
S
E
A
S
S
A
S
E
Site 79
S538
S
A
S
T
S
E
A
S
S
A
S
E
T
S
T
Site 80
S539
A
S
T
S
E
A
S
S
A
S
E
T
S
T
T
Site 81
S541
T
S
E
A
S
S
A
S
E
T
S
T
T
Q
T
Site 82
T543
E
A
S
S
A
S
E
T
S
T
T
Q
T
T
S
Site 83
T545
S
S
A
S
E
T
S
T
T
Q
T
T
S
T
P
Site 84
T546
S
A
S
E
T
S
T
T
Q
T
T
S
T
P
L
Site 85
T548
S
E
T
S
T
T
Q
T
T
S
T
P
L
S
S
Site 86
T549
E
T
S
T
T
Q
T
T
S
T
P
L
S
S
P
Site 87
S550
T
S
T
T
Q
T
T
S
T
P
L
S
S
P
L
Site 88
T551
S
T
T
Q
T
T
S
T
P
L
S
S
P
L
G
Site 89
S554
Q
T
T
S
T
P
L
S
S
P
L
G
T
S
Q
Site 90
S555
T
T
S
T
P
L
S
S
P
L
G
T
S
Q
V
Site 91
T651
S
G
G
S
L
P
I
T
S
L
D
A
T
G
N
Site 92
S708
G
N
S
A
P
V
A
S
L
H
A
T
S
T
S
Site 93
S713
V
A
S
L
H
A
T
S
T
S
A
E
S
I
Q
Site 94
T714
A
S
L
H
A
T
S
T
S
A
E
S
I
Q
N
Site 95
S715
S
L
H
A
T
S
T
S
A
E
S
I
Q
N
S
Site 96
S718
A
T
S
T
S
A
E
S
I
Q
N
S
L
F
T
Site 97
S734
A
S
A
S
G
A
A
S
T
T
T
T
A
S
K
Site 98
T738
G
A
A
S
T
T
T
T
A
S
K
A
Q
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation