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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NM23
Full Name:
Nucleoside diphosphate kinase A
Alias:
EC 2.7.4.6; Metastasis inhibition factor nm23; NDK A; NDKA; NDP kinase A; NDPKA; NM23-H1; NME1; Non-metastatic cells 1, protein (NM23A) expressed in; Tumor metastatic process-associated protein; Tumour metastatic process-associated protein
Type:
Nucleotide Metabolism - pyrimidine; EC 2.7.4.6; Nucleotide Metabolism - purine; Tumor suppressor; Kinase (non-protein)
Mass (Da):
17149
Number AA:
152
UniProt ID:
P15531
International Prot ID:
IPI00012048
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005525
GO:0004536
PhosphoSite+
KinaseNET
Biological Process:
GO:0006241
GO:0006183
GO:0006228
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S44
G
L
K
F
M
Q
A
S
E
D
L
L
K
E
H
Site 2
Y52
E
D
L
L
K
E
H
Y
V
D
L
K
D
R
P
Site 3
Y67
F
F
A
G
L
V
K
Y
M
H
S
G
P
V
V
Site 4
T94
G
R
V
M
L
G
E
T
N
P
A
D
S
K
P
Site 5
S99
G
E
T
N
P
A
D
S
K
P
G
T
I
R
G
Site 6
T103
P
A
D
S
K
P
G
T
I
R
G
D
F
C
I
Site 7
S120
G
R
N
I
I
H
G
S
D
S
V
E
S
A
E
Site 8
S122
N
I
I
H
G
S
D
S
V
E
S
A
E
K
E
Site 9
S125
H
G
S
D
S
V
E
S
A
E
K
E
I
G
L
Site 10
Y142
H
P
E
E
L
V
D
Y
T
S
C
A
Q
N
W
Site 11
S144
E
E
L
V
D
Y
T
S
C
A
Q
N
W
I
Y
Site 12
Y151
S
C
A
Q
N
W
I
Y
E
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation