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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RPA2
Full Name:
Replication protein A 32 kDa subunit
Alias:
REPA2; Replication factor-A protein 2; Replication protein A2; Replication protein A2, 32kDa; RF-A; RP-A; RPA32
Type:
DNA replication protein
Mass (Da):
29247
Number AA:
270
UniProt ID:
P15927
International Prot ID:
IPI00013939
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005662
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003697
PhosphoSite+
KinaseNET
Biological Process:
GO:0006261
GO:0000718
GO:0006297
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
W
N
S
G
F
E
S
Y
G
S
Site 2
S8
M
W
N
S
G
F
E
S
Y
G
S
S
S
Y
G
Site 3
Y9
W
N
S
G
F
E
S
Y
G
S
S
S
Y
G
G
Site 4
S11
S
G
F
E
S
Y
G
S
S
S
Y
G
G
A
G
Site 5
S12
G
F
E
S
Y
G
S
S
S
Y
G
G
A
G
G
Site 6
S13
F
E
S
Y
G
S
S
S
Y
G
G
A
G
G
Y
Site 7
Y14
E
S
Y
G
S
S
S
Y
G
G
A
G
G
Y
T
Site 8
Y20
S
Y
G
G
A
G
G
Y
T
Q
S
P
G
G
F
Site 9
T21
Y
G
G
A
G
G
Y
T
Q
S
P
G
G
F
G
Site 10
S23
G
A
G
G
Y
T
Q
S
P
G
G
F
G
S
P
Site 11
S29
Q
S
P
G
G
F
G
S
P
A
P
S
Q
A
E
Site 12
S33
G
F
G
S
P
A
P
S
Q
A
E
K
K
S
R
Site 13
S39
P
S
Q
A
E
K
K
S
R
A
R
A
Q
H
I
Site 14
S52
H
I
V
P
C
T
I
S
Q
L
L
S
A
T
L
Site 15
S72
R
I
G
N
V
E
I
S
Q
V
T
I
V
G
I
Site 16
T88
R
H
A
E
K
A
P
T
N
I
V
Y
K
I
D
Site 17
T98
V
Y
K
I
D
D
M
T
A
A
P
M
D
V
R
Site 18
T110
D
V
R
Q
W
V
D
T
D
D
T
S
S
E
N
Site 19
T113
Q
W
V
D
T
D
D
T
S
S
E
N
T
V
V
Site 20
S114
W
V
D
T
D
D
T
S
S
E
N
T
V
V
P
Site 21
S115
V
D
T
D
D
T
S
S
E
N
T
V
V
P
P
Site 22
T118
D
D
T
S
S
E
N
T
V
V
P
P
E
T
Y
Site 23
T124
N
T
V
V
P
P
E
T
Y
V
K
V
A
G
H
Site 24
S134
K
V
A
G
H
L
R
S
F
Q
N
K
K
S
L
Site 25
S140
R
S
F
Q
N
K
K
S
L
V
A
F
K
I
M
Site 26
S170
I
N
A
H
M
V
L
S
K
A
N
S
Q
P
S
Site 27
S174
M
V
L
S
K
A
N
S
Q
P
S
A
G
R
A
Site 28
S177
S
K
A
N
S
Q
P
S
A
G
R
A
P
I
S
Site 29
S184
S
A
G
R
A
P
I
S
N
P
G
M
S
E
A
Site 30
S189
P
I
S
N
P
G
M
S
E
A
G
N
F
G
G
Site 31
S198
A
G
N
F
G
G
N
S
F
M
P
A
N
G
L
Site 32
S238
K
N
Q
L
K
H
M
S
V
S
S
I
K
Q
A
Site 33
S250
K
Q
A
V
D
F
L
S
N
E
G
H
I
Y
S
Site 34
Y256
L
S
N
E
G
H
I
Y
S
T
V
D
D
D
H
Site 35
S257
S
N
E
G
H
I
Y
S
T
V
D
D
D
H
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation