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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UBTF
Full Name:
Nucleolar transcription factor 1
Alias:
Autoantigen NOR-90; NOR-90; TCFUBF; UBF1; UBF-1; Upstream binding factor 1; Upstream binding transcription factor, RNA polymerase I; Upstream-binding factor 1
Type:
Transcription protein
Mass (Da):
89406
Number AA:
764
UniProt ID:
P17480
International Prot ID:
IPI00014533
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003701
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006356
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
N
G
E
A
D
C
P
T
D
L
E
M
A
A
P
Site 2
S23
P
K
G
Q
D
R
W
S
Q
E
D
M
L
T
L
Site 3
S40
C
M
K
N
N
L
P
S
N
D
S
S
K
F
K
Site 4
S43
N
N
L
P
S
N
D
S
S
K
F
K
T
T
E
Site 5
S44
N
L
P
S
N
D
S
S
K
F
K
T
T
E
S
Site 6
T48
N
D
S
S
K
F
K
T
T
E
S
H
M
D
W
Site 7
S64
K
V
A
F
K
D
F
S
G
D
M
C
K
L
K
Site 8
T86
V
R
K
F
R
T
L
T
E
L
I
L
D
A
Q
Site 9
T117
D
F
P
K
K
P
L
T
P
Y
F
R
F
F
M
Site 10
Y119
P
K
K
P
L
T
P
Y
F
R
F
F
M
E
K
Site 11
Y130
F
M
E
K
R
A
K
Y
A
K
L
H
P
E
M
Site 12
S138
A
K
L
H
P
E
M
S
N
L
D
L
T
K
I
Site 13
T143
E
M
S
N
L
D
L
T
K
I
L
S
K
K
Y
Site 14
S147
L
D
L
T
K
I
L
S
K
K
Y
K
E
L
P
Site 15
Y150
T
K
I
L
S
K
K
Y
K
E
L
P
E
K
K
Site 16
Y161
P
E
K
K
K
M
K
Y
I
Q
D
F
Q
R
E
Site 17
S193
L
I
Q
N
A
K
K
S
D
I
P
E
K
P
K
Site 18
T201
D
I
P
E
K
P
K
T
P
Q
Q
L
W
Y
T
Site 19
Y207
K
T
P
Q
Q
L
W
Y
T
H
E
K
K
V
Y
Site 20
Y214
Y
T
H
E
K
K
V
Y
L
K
V
R
P
D
A
Site 21
T223
K
V
R
P
D
A
T
T
K
E
V
K
D
S
L
Site 22
S229
T
T
K
E
V
K
D
S
L
G
K
Q
W
S
Q
Site 23
S235
D
S
L
G
K
Q
W
S
Q
L
S
D
K
K
R
Site 24
S238
G
K
Q
W
S
Q
L
S
D
K
K
R
L
K
W
Site 25
Y256
A
L
E
Q
R
K
E
Y
E
E
I
M
R
D
Y
Site 26
Y263
Y
E
E
I
M
R
D
Y
I
Q
K
H
P
E
L
Site 27
S273
K
H
P
E
L
N
I
S
E
E
G
I
T
K
S
Site 28
T278
N
I
S
E
E
G
I
T
K
S
T
L
T
K
A
Site 29
S280
S
E
E
G
I
T
K
S
T
L
T
K
A
E
R
Site 30
T298
D
K
F
D
G
R
P
T
K
P
P
P
N
S
Y
Site 31
S304
P
T
K
P
P
P
N
S
Y
S
L
Y
C
A
E
Site 32
S306
K
P
P
P
N
S
Y
S
L
Y
C
A
E
L
M
Site 33
Y308
P
P
N
S
Y
S
L
Y
C
A
E
L
M
A
N
Site 34
S321
A
N
M
K
D
V
P
S
T
E
R
M
V
L
C
Site 35
T322
N
M
K
D
V
P
S
T
E
R
M
V
L
C
S
Site 36
S329
T
E
R
M
V
L
C
S
Q
Q
W
K
L
L
S
Site 37
S336
S
Q
Q
W
K
L
L
S
Q
K
E
K
D
A
Y
Site 38
Y343
S
Q
K
E
K
D
A
Y
H
K
K
C
D
Q
K
Site 39
Y354
C
D
Q
K
K
K
D
Y
E
V
E
L
L
R
F
Site 40
S364
E
L
L
R
F
L
E
S
L
P
E
E
E
Q
Q
Site 41
T388
N
I
N
K
K
Q
A
T
S
P
A
S
K
K
P
Site 42
S389
I
N
K
K
Q
A
T
S
P
A
S
K
K
P
A
Site 43
S392
K
Q
A
T
S
P
A
S
K
K
P
A
Q
E
G
Site 44
S404
Q
E
G
G
K
G
G
S
E
K
P
K
R
P
V
Site 45
S412
E
K
P
K
R
P
V
S
A
M
F
I
F
S
E
Site 46
S433
Q
E
E
R
P
E
L
S
E
S
E
L
T
R
L
Site 47
S435
E
R
P
E
L
S
E
S
E
L
T
R
L
L
A
Site 48
T438
E
L
S
E
S
E
L
T
R
L
L
A
R
M
W
Site 49
S449
A
R
M
W
N
D
L
S
E
K
K
K
A
K
Y
Site 50
Y456
S
E
K
K
K
A
K
Y
K
A
R
E
A
A
L
Site 51
S467
E
A
A
L
K
A
Q
S
E
R
K
P
G
G
E
Site 52
S484
E
R
G
K
L
P
E
S
P
K
R
A
E
E
I
Site 53
S495
A
E
E
I
W
Q
Q
S
V
I
G
D
Y
L
A
Site 54
Y500
Q
Q
S
V
I
G
D
Y
L
A
R
F
K
N
D
Site 55
Y541
A
A
E
D
Q
K
R
Y
E
R
E
L
S
E
M
Site 56
S546
K
R
Y
E
R
E
L
S
E
M
R
A
P
P
A
Site 57
S557
A
P
P
A
A
T
N
S
S
K
K
M
K
F
Q
Site 58
Y575
K
K
P
P
M
N
G
Y
Q
K
F
S
Q
E
L
Site 59
S579
M
N
G
Y
Q
K
F
S
Q
E
L
L
S
N
G
Site 60
S584
K
F
S
Q
E
L
L
S
N
G
E
L
N
H
L
Site 61
S602
E
R
M
V
E
I
G
S
R
W
Q
R
I
S
Q
Site 62
S608
G
S
R
W
Q
R
I
S
Q
S
Q
K
E
H
Y
Site 63
S610
R
W
Q
R
I
S
Q
S
Q
K
E
H
Y
K
K
Site 64
S636
H
L
D
L
W
V
K
S
L
S
P
Q
D
R
A
Site 65
S638
D
L
W
V
K
S
L
S
P
Q
D
R
A
A
Y
Site 66
Y645
S
P
Q
D
R
A
A
Y
K
E
Y
I
S
N
K
Site 67
S650
A
A
Y
K
E
Y
I
S
N
K
R
K
S
M
T
Site 68
S655
Y
I
S
N
K
R
K
S
M
T
K
L
R
G
P
Site 69
T657
S
N
K
R
K
S
M
T
K
L
R
G
P
N
P
Site 70
S666
L
R
G
P
N
P
K
S
S
R
T
T
L
Q
S
Site 71
S667
R
G
P
N
P
K
S
S
R
T
T
L
Q
S
K
Site 72
T669
P
N
P
K
S
S
R
T
T
L
Q
S
K
S
E
Site 73
T670
N
P
K
S
S
R
T
T
L
Q
S
K
S
E
S
Site 74
S673
S
S
R
T
T
L
Q
S
K
S
E
S
E
E
D
Site 75
S675
R
T
T
L
Q
S
K
S
E
S
E
E
D
D
E
Site 76
S677
T
L
Q
S
K
S
E
S
E
E
D
D
E
E
D
Site 77
S702
E
D
D
E
N
G
D
S
S
E
D
G
G
D
S
Site 78
S703
D
D
E
N
G
D
S
S
E
D
G
G
D
S
S
Site 79
S709
S
S
E
D
G
G
D
S
S
E
S
S
S
E
D
Site 80
S710
S
E
D
G
G
D
S
S
E
S
S
S
E
D
E
Site 81
S712
D
G
G
D
S
S
E
S
S
S
E
D
E
S
E
Site 82
S713
G
G
D
S
S
E
S
S
S
E
D
E
S
E
D
Site 83
S714
G
D
S
S
E
S
S
S
E
D
E
S
E
D
G
Site 84
S718
E
S
S
S
E
D
E
S
E
D
G
D
E
N
E
Site 85
S745
D
E
D
E
D
N
E
S
E
G
S
S
S
S
S
Site 86
S748
E
D
N
E
S
E
G
S
S
S
S
S
S
S
S
Site 87
S749
D
N
E
S
E
G
S
S
S
S
S
S
S
S
G
Site 88
S750
N
E
S
E
G
S
S
S
S
S
S
S
S
G
D
Site 89
S751
E
S
E
G
S
S
S
S
S
S
S
S
G
D
S
Site 90
S752
S
E
G
S
S
S
S
S
S
S
S
G
D
S
S
Site 91
S753
E
G
S
S
S
S
S
S
S
S
G
D
S
S
D
Site 92
S754
G
S
S
S
S
S
S
S
S
G
D
S
S
D
S
Site 93
S755
S
S
S
S
S
S
S
S
G
D
S
S
D
S
D
Site 94
S758
S
S
S
S
S
G
D
S
S
D
S
D
S
N
_
Site 95
S759
S
S
S
S
G
D
S
S
D
S
D
S
N
_
_
Site 96
S761
S
S
G
D
S
S
D
S
D
S
N
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation