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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDH2
Full Name:
Cadherin-2
Alias:
CADH2; Cadherin 2, type 1, N-cadherin (neuronal); Cadherin, neural; Cadherin-2; CD325; CDHN; CDw325; NCAD; N-cad; N-cadherin; Neural-cadherin
Type:
Adhesion protein
Mass (Da):
99809
Number AA:
906
UniProt ID:
P19022
International Prot ID:
IPI00290085
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y41
T
G
F
P
E
D
V
Y
S
A
V
L
S
K
D
Site 2
S42
G
F
P
E
D
V
Y
S
A
V
L
S
K
D
V
Site 3
S46
D
V
Y
S
A
V
L
S
K
D
V
H
E
G
Q
Site 4
S61
P
L
L
N
V
K
F
S
N
C
N
G
K
R
K
Site 5
Y71
N
G
K
R
K
V
Q
Y
E
S
S
E
P
A
D
Site 6
S74
R
K
V
Q
Y
E
S
S
E
P
A
D
F
K
V
Site 7
S92
G
M
V
Y
A
V
R
S
F
P
L
S
S
E
H
Site 8
S96
A
V
R
S
F
P
L
S
S
E
H
A
K
F
L
Site 9
T126
V
K
L
S
L
K
P
T
L
T
E
E
S
V
K
Site 10
T128
L
S
L
K
P
T
L
T
E
E
S
V
K
E
S
Site 11
S131
K
P
T
L
T
E
E
S
V
K
E
S
A
E
V
Site 12
S135
T
E
E
S
V
K
E
S
A
E
V
E
E
I
V
Site 13
S148
I
V
F
P
R
Q
F
S
K
H
S
G
H
L
Q
Site 14
T454
V
K
P
I
D
F
E
T
N
R
M
F
V
L
T
Site 15
Y496
I
D
V
N
E
N
P
Y
F
A
P
N
P
K
I
Site 16
Y773
V
R
D
N
I
L
K
Y
D
E
E
G
G
G
E
Site 17
Y785
G
G
E
E
D
Q
D
Y
D
L
S
Q
L
Q
Q
Site 18
S788
E
D
Q
D
Y
D
L
S
Q
L
Q
Q
P
D
T
Site 19
T795
S
Q
L
Q
Q
P
D
T
V
E
P
D
A
I
K
Site 20
Y820
P
I
H
A
E
P
Q
Y
P
V
R
S
A
A
P
Site 21
S824
E
P
Q
Y
P
V
R
S
A
A
P
H
P
G
D
Site 22
T848
K
A
A
D
N
D
P
T
A
P
P
Y
D
S
L
Site 23
Y852
N
D
P
T
A
P
P
Y
D
S
L
L
V
F
D
Site 24
S854
P
T
A
P
P
Y
D
S
L
L
V
F
D
Y
E
Site 25
Y860
D
S
L
L
V
F
D
Y
E
G
S
G
S
T
A
Site 26
S863
L
V
F
D
Y
E
G
S
G
S
T
A
G
S
L
Site 27
S865
F
D
Y
E
G
S
G
S
T
A
G
S
L
S
S
Site 28
S869
G
S
G
S
T
A
G
S
L
S
S
L
N
S
S
Site 29
S871
G
S
T
A
G
S
L
S
S
L
N
S
S
S
S
Site 30
S872
S
T
A
G
S
L
S
S
L
N
S
S
S
S
G
Site 31
S875
G
S
L
S
S
L
N
S
S
S
S
G
G
E
Q
Site 32
S876
S
L
S
S
L
N
S
S
S
S
G
G
E
Q
D
Site 33
S877
L
S
S
L
N
S
S
S
S
G
G
E
Q
D
Y
Site 34
S878
S
S
L
N
S
S
S
S
G
G
E
Q
D
Y
D
Site 35
Y884
S
S
G
G
E
Q
D
Y
D
Y
L
N
D
W
G
Site 36
Y886
G
G
E
Q
D
Y
D
Y
L
N
D
W
G
P
R
Site 37
Y901
F
K
K
L
A
D
M
Y
G
G
G
D
D
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation