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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
G-alpha(z)
Full Name:
Guanine nucleotide-binding protein G(z) subunit alpha
Alias:
G(x) alpha; GNAZ; guanine nucleotide binding protein (G protein) alpha z; guanine nucleotide binding protein (G protein) alpha z polypeptide; guanine nucleotide-binding protein G(z), alpha; Gz-alpha
Type:
G protein, heterotrimeric; Nuclear envelope; Endoplasmic reticulum
Mass (Da):
40924
Number AA:
354
UniProt ID:
P19086
International Prot ID:
IPI00328128
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031225
GO:0005783
GO:0005635
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005057
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
C
R
Q
S
S
E
E
K
E
A
A
Site 2
S7
_
M
G
C
R
Q
S
S
E
E
K
E
A
A
R
Site 3
S16
E
K
E
A
A
R
R
S
R
R
I
D
R
H
L
Site 4
S25
D
R
H
L
R
S
E
S
Q
R
Q
R
R
E
I
Site 5
S27
D
R
H
L
R
S
E
S
Q
R
Q
R
R
E
I
Site 6
S47
G
T
S
N
S
G
K
S
T
I
V
K
Q
M
K
Site 7
T48
T
S
N
S
G
K
S
T
I
V
K
Q
M
K
I
Site 8
Y75
E
Y
K
P
L
I
I
Y
N
A
I
D
S
L
T
Site 9
Y102
F
H
N
P
D
R
A
Y
D
A
V
Q
L
F
A
Site 10
S142
P
G
A
Q
A
C
F
S
R
S
S
E
Y
H
L
Site 11
S144
A
Q
A
C
F
S
R
S
S
E
Y
H
L
E
D
Site 12
S145
Q
A
C
F
S
R
S
S
E
Y
H
L
E
D
N
Site 13
Y147
C
F
S
R
S
S
E
Y
H
L
E
D
N
A
A
Site 14
Y155
H
L
E
D
N
A
A
Y
Y
L
N
D
L
E
R
Site 15
Y156
L
E
D
N
A
A
Y
Y
L
N
D
L
E
R
I
Site 16
T182
I
L
R
S
R
D
M
T
T
G
I
V
E
N
K
Site 17
T191
G
I
V
E
N
K
F
T
F
K
E
L
T
F
K
Site 18
S207
V
D
V
G
G
Q
R
S
E
R
K
K
W
I
H
Site 19
Y231
F
C
V
E
L
S
G
Y
D
L
K
L
Y
E
D
Site 20
Y236
S
G
Y
D
L
K
L
Y
E
D
N
Q
T
S
R
Site 21
T241
K
L
Y
E
D
N
Q
T
S
R
M
A
E
S
L
Site 22
S242
L
Y
E
D
N
Q
T
S
R
M
A
E
S
L
R
Site 23
S247
Q
T
S
R
M
A
E
S
L
R
L
F
D
S
I
Site 24
T285
K
I
R
R
I
P
L
T
I
C
F
P
E
Y
K
Site 25
Y291
L
T
I
C
F
P
E
Y
K
G
Q
N
T
Y
E
Site 26
Y303
T
Y
E
E
A
A
V
Y
I
Q
R
Q
F
E
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation