KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
RXRA
Full Name:
Retinoic acid receptor RXR-alpha
Alias:
NR2B1; Retinoid X receptor alpha; Retinoid X receptor, alpha
Type:
Transcription protein (receptor)
Mass (Da):
50811
Number AA:
462
UniProt ID:
P19793
International Prot ID:
IPI00418394
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003706
GO:0004886
GO:0043565
PhosphoSite+
KinaseNET
Biological Process:
GO:0008203
GO:0044419
GO:0010553
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
H
F
L
P
L
D
F
S
T
Q
V
N
S
S
L
Site 2
S17
D
F
S
T
Q
V
N
S
S
L
T
S
P
T
G
Site 3
S18
F
S
T
Q
V
N
S
S
L
T
S
P
T
G
R
Site 4
S21
Q
V
N
S
S
L
T
S
P
T
G
R
G
S
M
Site 5
T23
N
S
S
L
T
S
P
T
G
R
G
S
M
A
A
Site 6
S27
T
S
P
T
G
R
G
S
M
A
A
P
S
L
H
Site 7
S32
R
G
S
M
A
A
P
S
L
H
P
S
L
G
P
Site 8
S43
S
L
G
P
G
I
G
S
P
G
Q
L
H
S
P
Site 9
S49
G
S
P
G
Q
L
H
S
P
I
S
T
L
S
S
Site 10
S52
G
Q
L
H
S
P
I
S
T
L
S
S
P
I
N
Site 11
T53
Q
L
H
S
P
I
S
T
L
S
S
P
I
N
G
Site 12
S55
H
S
P
I
S
T
L
S
S
P
I
N
G
M
G
Site 13
S56
S
P
I
S
T
L
S
S
P
I
N
G
M
G
P
Site 14
S69
G
P
P
F
S
V
I
S
S
P
M
G
P
H
S
Site 15
S70
P
P
F
S
V
I
S
S
P
M
G
P
H
S
M
Site 16
S76
S
S
P
M
G
P
H
S
M
S
V
P
T
T
P
Site 17
S78
P
M
G
P
H
S
M
S
V
P
T
T
P
T
L
Site 18
T82
H
S
M
S
V
P
T
T
P
T
L
G
F
S
T
Site 19
S88
T
T
P
T
L
G
F
S
T
G
S
P
Q
L
S
Site 20
T89
T
P
T
L
G
F
S
T
G
S
P
Q
L
S
S
Site 21
S91
T
L
G
F
S
T
G
S
P
Q
L
S
S
P
M
Site 22
S95
S
T
G
S
P
Q
L
S
S
P
M
N
P
V
S
Site 23
S96
T
G
S
P
Q
L
S
S
P
M
N
P
V
S
S
Site 24
S102
S
S
P
M
N
P
V
S
S
S
E
D
I
K
P
Site 25
S103
S
P
M
N
P
V
S
S
S
E
D
I
K
P
P
Site 26
S104
P
M
N
P
V
S
S
S
E
D
I
K
P
P
L
Site 27
S124
L
K
V
P
A
H
P
S
G
N
M
A
S
F
T
Site 28
S143
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
Site 29
Y147
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
Site 30
Y150
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
Site 31
T162
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
Site 32
T168
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
Site 33
Y169
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
Site 34
T170
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
Site 35
S222
R
N
E
N
E
V
E
S
T
S
S
A
N
E
D
Site 36
S225
N
E
V
E
S
T
S
S
A
N
E
D
M
P
V
Site 37
T246
E
L
A
V
E
P
K
T
E
T
Y
V
E
A
N
Site 38
Y249
V
E
P
K
T
E
T
Y
V
E
A
N
M
G
L
Site 39
S259
A
N
M
G
L
N
P
S
S
P
N
D
P
V
T
Site 40
S260
N
M
G
L
N
P
S
S
P
N
D
P
V
T
N
Site 41
T266
S
S
P
N
D
P
V
T
N
I
C
Q
A
A
D
Site 42
S290
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
Site 43
S336
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
Site 44
S355
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
Site 45
T365
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
Site 46
S380
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
Site 47
S384
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
Site 48
Y397
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
Site 49
Y403
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Site 50
Y408
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation