KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
Nur77
Full Name:
Nuclear receptor subfamily 4 group A member 1
Alias:
Early response protein NAK1; GFRP; GFRP1; HMR; N10; N10 nuclear protein; NAK1; NAK-1; NGFIB; NGFI-B; NR4A1; Nuclear hormone receptor NUR/77; Nuclear receptor subfamily 4, group A, member 1; NUR77; Orphan nuclear receptor HMR; TR3; TR3 orphan receptor
Type:
Receptor, nuclear
Mass (Da):
64463
Number AA:
598
UniProt ID:
P22736
International Prot ID:
IPI00743108
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0003707
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
P
C
I
Q
A
Q
Y
G
T
P
A
P
S
P
Site 2
T10
C
I
Q
A
Q
Y
G
T
P
A
P
S
P
G
P
Site 3
S14
Q
Y
G
T
P
A
P
S
P
G
P
R
D
H
L
Site 4
S23
G
P
R
D
H
L
A
S
D
P
L
T
P
E
F
Site 5
T27
H
L
A
S
D
P
L
T
P
E
F
I
K
P
T
Site 6
S39
K
P
T
M
D
L
A
S
P
E
A
A
P
A
A
Site 7
S54
P
T
A
L
P
S
F
S
T
F
M
D
G
Y
T
Site 8
Y60
F
S
T
F
M
D
G
Y
T
G
E
F
D
T
F
Site 9
T61
S
T
F
M
D
G
Y
T
G
E
F
D
T
F
L
Site 10
T66
G
Y
T
G
E
F
D
T
F
L
Y
Q
L
P
G
Site 11
Y69
G
E
F
D
T
F
L
Y
Q
L
P
G
T
V
Q
Site 12
S79
P
G
T
V
Q
P
C
S
S
A
S
S
S
A
S
Site 13
S80
G
T
V
Q
P
C
S
S
A
S
S
S
A
S
S
Site 14
S82
V
Q
P
C
S
S
A
S
S
S
A
S
S
T
S
Site 15
S83
Q
P
C
S
S
A
S
S
S
A
S
S
T
S
S
Site 16
S84
P
C
S
S
A
S
S
S
A
S
S
T
S
S
S
Site 17
S86
S
S
A
S
S
S
A
S
S
T
S
S
S
S
A
Site 18
S87
S
A
S
S
S
A
S
S
T
S
S
S
S
A
T
Site 19
T88
A
S
S
S
A
S
S
T
S
S
S
S
A
T
S
Site 20
S89
S
S
S
A
S
S
T
S
S
S
S
A
T
S
P
Site 21
S90
S
S
A
S
S
T
S
S
S
S
A
T
S
P
A
Site 22
S91
S
A
S
S
T
S
S
S
S
A
T
S
P
A
S
Site 23
S92
A
S
S
T
S
S
S
S
A
T
S
P
A
S
A
Site 24
T94
S
T
S
S
S
S
A
T
S
P
A
S
A
S
F
Site 25
S95
T
S
S
S
S
A
T
S
P
A
S
A
S
F
K
Site 26
S98
S
S
A
T
S
P
A
S
A
S
F
K
F
E
D
Site 27
S100
A
T
S
P
A
S
A
S
F
K
F
E
D
F
Q
Site 28
Y109
K
F
E
D
F
Q
V
Y
G
C
Y
P
G
P
L
Site 29
Y112
D
F
Q
V
Y
G
C
Y
P
G
P
L
S
G
P
Site 30
S117
G
C
Y
P
G
P
L
S
G
P
V
D
E
A
L
Site 31
S125
G
P
V
D
E
A
L
S
S
S
G
S
D
Y
Y
Site 32
S126
P
V
D
E
A
L
S
S
S
G
S
D
Y
Y
G
Site 33
S127
V
D
E
A
L
S
S
S
G
S
D
Y
Y
G
S
Site 34
S129
E
A
L
S
S
S
G
S
D
Y
Y
G
S
P
C
Site 35
Y131
L
S
S
S
G
S
D
Y
Y
G
S
P
C
S
A
Site 36
Y132
S
S
S
G
S
D
Y
Y
G
S
P
C
S
A
P
Site 37
S134
S
G
S
D
Y
Y
G
S
P
C
S
A
P
S
P
Site 38
S137
D
Y
Y
G
S
P
C
S
A
P
S
P
S
T
P
Site 39
S140
G
S
P
C
S
A
P
S
P
S
T
P
S
F
Q
Site 40
S142
P
C
S
A
P
S
P
S
T
P
S
F
Q
P
P
Site 41
T143
C
S
A
P
S
P
S
T
P
S
F
Q
P
P
Q
Site 42
S145
A
P
S
P
S
T
P
S
F
Q
P
P
Q
L
S
Site 43
S152
S
F
Q
P
P
Q
L
S
P
W
D
G
S
F
G
Site 44
S157
Q
L
S
P
W
D
G
S
F
G
H
F
S
P
S
Site 45
S162
D
G
S
F
G
H
F
S
P
S
Q
T
Y
E
G
Site 46
S164
S
F
G
H
F
S
P
S
Q
T
Y
E
G
L
R
Site 47
T166
G
H
F
S
P
S
Q
T
Y
E
G
L
R
A
W
Site 48
T174
Y
E
G
L
R
A
W
T
E
Q
L
P
K
A
S
Site 49
S181
T
E
Q
L
P
K
A
S
G
P
P
Q
P
P
A
Site 50
S191
P
Q
P
P
A
F
F
S
F
S
P
P
T
G
P
Site 51
S193
P
P
A
F
F
S
F
S
P
P
T
G
P
S
P
Site 52
T196
F
F
S
F
S
P
P
T
G
P
S
P
S
L
A
Site 53
S199
F
S
P
P
T
G
P
S
P
S
L
A
Q
S
P
Site 54
S201
P
P
T
G
P
S
P
S
L
A
Q
S
P
L
K
Site 55
S205
P
S
P
S
L
A
Q
S
P
L
K
L
F
P
S
Site 56
S212
S
P
L
K
L
F
P
S
Q
A
T
H
Q
L
G
Site 57
S223
H
Q
L
G
E
G
E
S
Y
S
M
P
T
A
F
Site 58
Y224
Q
L
G
E
G
E
S
Y
S
M
P
T
A
F
P
Site 59
S225
L
G
E
G
E
S
Y
S
M
P
T
A
F
P
G
Site 60
T228
G
E
S
Y
S
M
P
T
A
F
P
G
L
A
P
Site 61
S237
F
P
G
L
A
P
T
S
P
H
L
E
G
S
G
Site 62
T248
E
G
S
G
I
L
D
T
P
V
T
S
T
K
A
Site 63
T251
G
I
L
D
T
P
V
T
S
T
K
A
R
S
G
Site 64
T253
L
D
T
P
V
T
S
T
K
A
R
S
G
A
P
Site 65
S257
V
T
S
T
K
A
R
S
G
A
P
G
G
S
E
Site 66
Y279
D
N
A
S
C
Q
H
Y
G
V
R
T
C
E
G
Site 67
T294
C
K
G
F
F
K
R
T
V
Q
K
N
A
K
Y
Site 68
Y301
T
V
Q
K
N
A
K
Y
I
C
L
A
N
K
D
Site 69
T339
M
V
K
E
V
V
R
T
D
S
L
K
G
R
R
Site 70
S341
K
E
V
V
R
T
D
S
L
K
G
R
R
G
R
Site 71
S351
G
R
R
G
R
L
P
S
K
P
K
Q
P
P
D
Site 72
S360
P
K
Q
P
P
D
A
S
P
A
N
L
L
T
S
Site 73
S375
L
V
R
A
H
L
D
S
G
P
S
T
A
K
L
Site 74
S378
A
H
L
D
S
G
P
S
T
A
K
L
D
Y
S
Site 75
T379
H
L
D
S
G
P
S
T
A
K
L
D
Y
S
K
Site 76
Y384
P
S
T
A
K
L
D
Y
S
K
F
Q
E
L
V
Site 77
S385
S
T
A
K
L
D
Y
S
K
F
Q
E
L
V
L
Site 78
S411
Q
Q
F
Y
D
L
L
S
G
S
L
E
V
I
R
Site 79
S431
I
P
G
F
A
E
L
S
P
A
D
Q
D
L
L
Site 80
Y453
L
F
I
L
R
L
A
Y
R
S
K
P
G
E
G
Site 81
S455
I
L
R
L
A
Y
R
S
K
P
G
E
G
K
L
Site 82
S533
E
L
Q
N
R
I
A
S
C
L
K
E
H
V
A
Site 83
S550
A
G
E
P
Q
P
A
S
C
L
S
R
L
L
G
Site 84
T564
G
K
L
P
E
L
R
T
L
C
T
Q
G
L
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation