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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GABRB3
Full Name:
Gamma-aminobutyric acid receptor subunit beta-3
Alias:
GABA(A) receptor; GABA(A) receptor subunit beta-3; Gamma-aminobutyric acid (GABA) A receptor, beta 3; Gamma-aminobutyric-acid receptor beta-3 subunit precursor; GBRB3
Type:
Channel, chloride; Channel, ligand-gated
Mass (Da):
54116
Number AA:
473
UniProt ID:
P28472
International Prot ID:
IPI00003467
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0034707
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0004890
GO:0005254
GO:0031404
PhosphoSite+
KinaseNET
Biological Process:
GO:0006811
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Gamma-aminobutyric acid receptor subunit beta-3 pan-specific antibody AB-NN254-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN254-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T288
T
T
V
L
T
M
T
T
I
N
T
H
L
R
E
Site 2
T296
I
N
T
H
L
R
E
T
L
P
K
I
P
Y
V
Site 3
Y302
E
T
L
P
K
I
P
Y
V
K
A
I
D
M
Y
Site 4
S354
A
K
A
K
N
D
R
S
K
S
E
S
N
R
V
Site 5
S356
A
K
N
D
R
S
K
S
E
S
N
R
V
D
A
Site 6
S358
N
D
R
S
K
S
E
S
N
R
V
D
A
H
G
Site 7
S371
H
G
N
I
L
L
T
S
L
E
V
H
N
E
M
Site 8
S391
G
I
G
D
T
R
N
S
A
I
S
F
D
N
S
Site 9
S394
D
T
R
N
S
A
I
S
F
D
N
S
G
I
Q
Site 10
S398
S
A
I
S
F
D
N
S
G
I
Q
Y
R
K
Q
Site 11
Y402
F
D
N
S
G
I
Q
Y
R
K
Q
S
M
P
R
Site 12
S406
G
I
Q
Y
R
K
Q
S
M
P
R
E
G
H
G
Site 13
S420
G
R
F
L
G
D
R
S
L
P
H
K
K
T
H
Site 14
T426
R
S
L
P
H
K
K
T
H
L
R
R
R
S
S
Site 15
S432
K
T
H
L
R
R
R
S
S
Q
L
K
I
K
I
Site 16
S433
T
H
L
R
R
R
S
S
Q
L
K
I
K
I
P
Site 17
T443
K
I
K
I
P
D
L
T
D
V
N
A
I
D
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation