PhosphoNET

           
Protein Info 
   
Short Name:  SHC1
Full Name:  SHC-transforming protein 1
Alias:  SHC (Src homology 2 domain containing) transforming protein 1; Src homology 2 domain-containing-transforming protein C1
Type:  Adapter/scaffold protein
Mass (Da):  62822
Number AA:  583
UniProt ID:  P29353
International Prot ID:  IPI00643176
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0070435  GO:0005829  GO:0005739 Uniprot OncoNet
Molecular Function:  GO:0005154  GO:0005158  GO:0005159 PhosphoSite+ KinaseNET
Biological Process:  GO:0007265  GO:0000187  GO:0007173 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y10LLPPKPKYNPLRNES
Site 2S17YNPLRNESLSSLEEG
Site 3S19PLRNESLSSLEEGAS
Site 4S20LRNESLSSLEEGASG
Site 5S26SSLEEGASGSTPPEE
Site 6S28LEEGASGSTPPEELP
Site 7T29EEGASGSTPPEELPS
Site 8S36TPPEELPSPSASSLG
Site 9S38PEELPSPSASSLGPI
Site 10S54PPLPGDDSPTTLCSF
Site 11T56LPGDDSPTTLCSFFP
Site 12T57PGDDSPTTLCSFFPR
Site 13S60DSPTTLCSFFPRMSN
Site 14S66CSFFPRMSNLRLANP
Site 15S80PAGGRPGSKGEPGRA
Site 16S115LQDMNKLSGGGGRRT
Site 17T122SGGGGRRTRVEGGQL
Site 18S139EEWTRHGSFVNKPTR
Site 19T145GSFVNKPTRGWLHPN
Site 20T206VPGAKGATRRRKPCS
Site 21S213TRRRKPCSRPLSSIL
Site 22S217KPCSRPLSSILGRSN
Site 23S218PCSRPLSSILGRSNL
Site 24S259IANHHMQSISFASGG
Site 25S261NHHMQSISFASGGDP
Site 26S264MQSISFASGGDPDTA
Site 27T270ASGGDPDTAEYVAYV
Site 28Y273GDPDTAEYVAYVAKD
Site 29Y276DTAEYVAYVAKDPVN
Site 30Y315FELRFKQYLRNPPKL
Site 31T324RNPPKLVTPHDRMAG
Site 32S335RMAGFDGSAWDEEEE
Site 33Y349EEPPDHQYYNDFPGK
Site 34Y350EPPDHQYYNDFPGKE
Site 35T380APGAARPTAPNAQTP
Site 36T386PTAPNAQTPSHLGAT
Site 37S426RELFDDPSYVNVQNL
Site 38Y427ELFDDPSYVNVQNLD
Site 39S453PNPAINGSAPRDLFD
Site 40S476RVPPPPQSVSMAEQL
Site 41S478PPPPQSVSMAEQLRG
Site 42S494PWFHGKLSRREAEAL
Site 43S513GDFLVRESTTTPGQY
Site 44T514DFLVRESTTTPGQYV
Site 45T516LVRESTTTPGQYVLT
Site 46Y520STTTPGQYVLTGLQS
Site 47T523TPGQYVLTGLQSGQP
Site 48S527YVLTGLQSGQPKHLL
Site 49S551TKDHRFESVSHLISY
Site 50Y558SVSHLISYHMDNHLP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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