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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STI1
Full Name:
Stress-induced-phosphoprotein 1
Alias:
HOP; Hsp70/Hsp90-organizing protein; IEFS; MSTI1; STIP1; Stress-induced-phosphoprotein 1; Transformation-sensitive protein IEF SSP 3521
Type:
Chaperone protein
Mass (Da):
62639
Number AA:
543
UniProt ID:
P31948
International Prot ID:
IPI00013894
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006950
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
E
K
G
N
K
A
L
S
V
G
N
I
D
D
A
Site 2
Y41
D
P
H
N
H
V
L
Y
S
N
R
S
A
A
Y
Site 3
S42
P
H
N
H
V
L
Y
S
N
R
S
A
A
Y
A
Site 4
Y48
Y
S
N
R
S
A
A
Y
A
K
K
G
D
Y
Q
Site 5
Y54
A
Y
A
K
K
G
D
Y
Q
K
A
Y
E
D
G
Site 6
Y58
K
G
D
Y
Q
K
A
Y
E
D
G
C
K
T
V
Site 7
T64
A
Y
E
D
G
C
K
T
V
D
L
K
P
D
W
Site 8
Y75
K
P
D
W
G
K
G
Y
S
R
K
A
A
A
L
Site 9
T94
R
F
E
E
A
K
R
T
Y
E
E
G
L
K
H
Site 10
Y95
F
E
E
A
K
R
T
Y
E
E
G
L
K
H
E
Site 11
Y134
P
F
N
M
P
N
L
Y
Q
K
L
E
S
D
P
Site 12
T143
K
L
E
S
D
P
R
T
R
T
L
L
S
D
P
Site 13
T145
E
S
D
P
R
T
R
T
L
L
S
D
P
T
Y
Site 14
S148
P
R
T
R
T
L
L
S
D
P
T
Y
R
E
L
Site 15
T151
R
T
L
L
S
D
P
T
Y
R
E
L
I
E
Q
Site 16
Y152
T
L
L
S
D
P
T
Y
R
E
L
I
E
Q
L
Site 17
S164
E
Q
L
R
N
K
P
S
D
L
G
T
K
L
Q
Site 18
T168
N
K
P
S
D
L
G
T
K
L
Q
D
P
R
I
Site 19
S189
L
L
G
V
D
L
G
S
M
D
E
E
E
E
I
Site 20
T198
D
E
E
E
E
I
A
T
P
P
P
P
P
P
P
Site 21
Y236
K
E
L
G
N
D
A
Y
K
K
K
D
F
D
T
Site 22
T243
Y
K
K
K
D
F
D
T
A
L
K
H
Y
D
K
Site 23
Y248
F
D
T
A
L
K
H
Y
D
K
A
K
E
L
D
Site 24
T257
K
A
K
E
L
D
P
T
N
M
T
Y
I
T
N
Site 25
Y269
I
T
N
Q
A
A
V
Y
F
E
K
G
D
Y
N
Site 26
Y275
V
Y
F
E
K
G
D
Y
N
K
C
R
E
L
C
Site 27
Y296
G
R
E
N
R
E
D
Y
R
Q
I
A
K
A
Y
Site 28
Y303
Y
R
Q
I
A
K
A
Y
A
R
I
G
N
S
Y
Site 29
Y310
Y
A
R
I
G
N
S
Y
F
K
E
E
K
Y
K
Site 30
Y316
S
Y
F
K
E
E
K
Y
K
D
A
I
H
F
Y
Site 31
S326
A
I
H
F
Y
N
K
S
L
A
E
H
R
T
P
Site 32
T332
K
S
L
A
E
H
R
T
P
D
V
L
K
K
C
Site 33
Y354
K
E
Q
E
R
L
A
Y
I
N
P
D
L
A
L
Site 34
Y376
E
C
F
Q
K
G
D
Y
P
Q
A
M
K
H
Y
Site 35
Y383
Y
P
Q
A
M
K
H
Y
T
E
A
I
K
R
N
Site 36
T384
P
Q
A
M
K
H
Y
T
E
A
I
K
R
N
P
Site 37
Y397
N
P
K
D
A
K
L
Y
S
N
R
A
A
C
Y
Site 38
S398
P
K
D
A
K
L
Y
S
N
R
A
A
C
Y
T
Site 39
T405
S
N
R
A
A
C
Y
T
K
L
L
E
F
Q
L
Site 40
T426
E
C
I
Q
L
E
P
T
F
I
K
G
Y
T
R
Site 41
Y431
E
P
T
F
I
K
G
Y
T
R
K
A
A
A
L
Site 42
Y444
A
L
E
A
M
K
D
Y
T
K
A
M
D
V
Y
Site 43
Y451
Y
T
K
A
M
D
V
Y
Q
K
A
L
D
L
D
Site 44
S459
Q
K
A
L
D
L
D
S
S
C
K
E
A
A
D
Site 45
S460
K
A
L
D
L
D
S
S
C
K
E
A
A
D
G
Site 46
Y468
C
K
E
A
A
D
G
Y
Q
R
C
M
M
A
Q
Site 47
Y476
Q
R
C
M
M
A
Q
Y
N
R
H
D
S
P
E
Site 48
S481
A
Q
Y
N
R
H
D
S
P
E
D
V
K
R
R
Site 49
S519
Q
K
D
P
Q
A
L
S
E
H
L
K
N
P
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation