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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDH5
Full Name:
Cadherin-5
Alias:
7B4; 7B4 antigen; CADH5; Cadherin 5, type 2; Cadherin-5; CD144; CD144 antigen; Vascular endothelial cadherin; Vascular endothelial-cadherin precursor; Vascular endothelium; VE-cadherin
Type:
Adhesion protein
Mass (Da):
87516
Number AA:
784
UniProt ID:
P33151
International Prot ID:
IPI00012792
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005102
PhosphoSite+
KinaseNET
Biological Process:
GO:0007156
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T35
A
N
P
A
Q
R
D
T
H
S
L
L
P
T
H
Site 2
S37
P
A
Q
R
D
T
H
S
L
L
P
T
H
R
R
Site 3
T41
D
T
H
S
L
L
P
T
H
R
R
Q
K
R
D
Site 4
T212
S
G
R
I
I
T
I
T
K
S
L
D
R
E
K
Site 5
Y223
D
R
E
K
Q
A
R
Y
E
I
V
V
E
A
R
Site 6
S634
Q
A
R
A
H
G
K
S
V
P
E
I
H
E
Q
Site 7
T644
E
I
H
E
Q
L
V
T
Y
D
E
E
G
G
G
Site 8
Y645
I
H
E
Q
L
V
T
Y
D
E
E
G
G
G
E
Site 9
T655
E
G
G
G
E
M
D
T
T
S
Y
D
V
S
V
Site 10
T656
G
G
G
E
M
D
T
T
S
Y
D
V
S
V
L
Site 11
S657
G
G
E
M
D
T
T
S
Y
D
V
S
V
L
N
Site 12
Y658
G
E
M
D
T
T
S
Y
D
V
S
V
L
N
S
Site 13
S661
D
T
T
S
Y
D
V
S
V
L
N
S
V
R
R
Site 14
S665
Y
D
V
S
V
L
N
S
V
R
R
G
G
A
K
Site 15
S683
P
A
L
D
A
R
P
S
L
Y
A
Q
V
Q
K
Site 16
Y685
L
D
A
R
P
S
L
Y
A
Q
V
Q
K
P
P
Site 17
Y725
H
D
G
D
G
P
P
Y
D
T
L
H
I
Y
G
Site 18
T727
G
D
G
P
P
Y
D
T
L
H
I
Y
G
Y
E
Site 19
Y731
P
Y
D
T
L
H
I
Y
G
Y
E
G
S
E
S
Site 20
Y733
D
T
L
H
I
Y
G
Y
E
G
S
E
S
I
A
Site 21
S736
H
I
Y
G
Y
E
G
S
E
S
I
A
E
S
L
Site 22
S738
Y
G
Y
E
G
S
E
S
I
A
E
S
L
S
S
Site 23
S742
G
S
E
S
I
A
E
S
L
S
S
L
G
T
D
Site 24
S744
E
S
I
A
E
S
L
S
S
L
G
T
D
S
S
Site 25
S745
S
I
A
E
S
L
S
S
L
G
T
D
S
S
D
Site 26
T748
E
S
L
S
S
L
G
T
D
S
S
D
S
D
V
Site 27
S750
L
S
S
L
G
T
D
S
S
D
S
D
V
D
Y
Site 28
S751
S
S
L
G
T
D
S
S
D
S
D
V
D
Y
D
Site 29
S753
L
G
T
D
S
S
D
S
D
V
D
Y
D
F
L
Site 30
Y757
S
S
D
S
D
V
D
Y
D
F
L
N
D
W
G
Site 31
Y774
F
K
M
L
A
E
L
Y
G
S
D
P
R
E
E
Site 32
S776
M
L
A
E
L
Y
G
S
D
P
R
E
E
L
L
Site 33
Y784
D
P
R
E
E
L
L
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation