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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RDX
Full Name:
Radixin
Alias:
Radixin isoform c
Type:
Cytoskeletal protein
Mass (Da):
68564
Number AA:
583
UniProt ID:
P35241
International Prot ID:
IPI00017367
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
GO:0051693
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
K
P
I
N
V
R
V
T
T
M
D
A
E
L
E
Site 2
T24
E
F
A
I
Q
P
N
T
T
G
K
Q
L
F
D
Site 3
Y49
V
W
F
F
G
L
Q
Y
V
D
S
K
G
Y
S
Site 4
S52
F
G
L
Q
Y
V
D
S
K
G
Y
S
T
W
L
Site 5
Y55
Q
Y
V
D
S
K
G
Y
S
T
W
L
K
L
N
Site 6
S56
Y
V
D
S
K
G
Y
S
T
W
L
K
L
N
K
Site 7
T66
L
K
L
N
K
K
V
T
Q
Q
D
V
K
K
E
Site 8
S90
K
F
F
P
E
D
V
S
E
E
L
I
Q
E
I
Site 9
T98
E
E
L
I
Q
E
I
T
Q
R
L
F
F
L
Q
Site 10
Y116
A
I
L
N
D
E
I
Y
C
P
P
E
T
A
V
Site 11
Y128
T
A
V
L
L
A
S
Y
A
V
Q
A
K
Y
G
Site 12
Y134
S
Y
A
V
Q
A
K
Y
G
D
Y
N
K
E
I
Site 13
Y137
V
Q
A
K
Y
G
D
Y
N
K
E
I
H
K
P
Site 14
Y146
K
E
I
H
K
P
G
Y
L
A
N
D
R
L
L
Site 15
S187
R
G
M
L
R
E
D
S
M
M
E
Y
L
K
I
Site 16
Y191
R
E
D
S
M
M
E
Y
L
K
I
A
Q
D
L
Site 17
Y205
L
E
M
Y
G
V
N
Y
F
E
I
K
N
K
K
Site 18
Y228
D
A
L
G
L
N
I
Y
E
H
D
D
K
L
T
Site 19
T235
Y
E
H
D
D
K
L
T
P
K
I
G
F
P
W
Site 20
S249
W
S
E
I
R
N
I
S
F
N
D
K
K
F
V
Site 21
Y270
K
A
P
D
F
V
F
Y
A
P
R
L
R
I
N
Site 22
Y291
C
M
G
N
H
E
L
Y
M
R
R
R
K
P
D
Site 23
T299
M
R
R
R
K
P
D
T
I
E
V
Q
Q
M
K
Site 24
T358
L
K
Q
I
E
E
Q
T
I
K
A
Q
K
E
L
Site 25
T369
Q
K
E
L
E
E
Q
T
R
K
A
L
E
L
D
Site 26
S401
R
A
A
E
E
A
K
S
A
I
A
K
Q
A
A
Site 27
T443
K
K
K
E
E
E
A
T
E
W
Q
H
K
A
F
Site 28
T459
A
Q
E
D
L
E
K
T
K
E
E
L
K
T
V
Site 29
T465
K
T
K
E
E
L
K
T
V
M
S
A
P
P
P
Site 30
S468
E
E
L
K
T
V
M
S
A
P
P
P
P
P
P
Site 31
T482
P
P
P
V
I
P
P
T
E
N
E
H
D
E
H
Site 32
S501
A
E
A
S
A
E
L
S
N
E
G
V
M
N
H
Site 33
S510
E
G
V
M
N
H
R
S
E
E
E
R
V
T
E
Site 34
T516
R
S
E
E
E
R
V
T
E
T
Q
K
N
E
R
Site 35
S533
K
Q
L
Q
A
L
S
S
E
L
A
Q
A
R
D
Site 36
T542
L
A
Q
A
R
D
E
T
K
K
T
Q
N
D
V
Site 37
T545
A
R
D
E
T
K
K
T
Q
N
D
V
L
H
A
Site 38
Y562
V
K
A
G
R
D
K
Y
K
T
L
R
Q
I
R
Site 39
T564
A
G
R
D
K
Y
K
T
L
R
Q
I
R
Q
G
Site 40
T573
R
Q
I
R
Q
G
N
T
K
Q
R
I
D
E
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation