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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AhR (aryl hydrocarbon receptor)
Full Name:
Aryl hydrocarbon receptor
Alias:
Class E basic helix-loop-helix protein 76
Type:
Receptor, transcription factor
Mass (Da):
96147
Number AA:
848
UniProt ID:
P35869
International Prot ID:
IPI00021008
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0051879
GO:0004879
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0007049
GO:0006950
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
N
S
S
S
A
N
I
T
Y
A
S
R
K
R
R
Site 2
Y10
S
S
S
A
N
I
T
Y
A
S
R
K
R
R
K
Site 3
S12
S
A
N
I
T
Y
A
S
R
K
R
R
K
P
V
Site 4
T22
R
R
K
P
V
Q
K
T
V
K
P
I
P
A
E
Site 5
S33
I
P
A
E
G
I
K
S
N
P
S
K
R
H
R
Site 6
S36
E
G
I
K
S
N
P
S
K
R
H
R
D
R
L
Site 7
T45
R
H
R
D
R
L
N
T
E
L
D
R
L
A
S
Site 8
S52
T
E
L
D
R
L
A
S
L
L
P
F
P
Q
D
Site 9
S68
I
N
K
L
D
K
L
S
V
L
R
L
S
V
S
Site 10
S75
S
V
L
R
L
S
V
S
Y
L
R
A
K
S
F
Site 11
Y76
V
L
R
L
S
V
S
Y
L
R
A
K
S
F
F
Site 12
S89
F
F
D
V
A
L
K
S
S
P
T
E
R
N
G
Site 13
S90
F
D
V
A
L
K
S
S
P
T
E
R
N
G
G
Site 14
T92
V
A
L
K
S
S
P
T
E
R
N
G
G
Q
D
Site 15
Y145
A
S
S
T
I
Q
D
Y
L
G
F
Q
Q
S
D
Site 16
S151
D
Y
L
G
F
Q
Q
S
D
V
I
H
Q
S
V
Site 17
S157
Q
S
D
V
I
H
Q
S
V
Y
E
L
I
H
T
Site 18
Y159
D
V
I
H
Q
S
V
Y
E
L
I
H
T
E
D
Site 19
T164
S
V
Y
E
L
I
H
T
E
D
R
A
E
F
Q
Site 20
S181
L
H
W
A
L
N
P
S
Q
C
T
E
S
G
Q
Site 21
T199
E
A
T
G
L
P
Q
T
V
V
C
Y
N
P
D
Site 22
S213
D
Q
I
P
P
E
N
S
P
L
M
E
R
C
F
Site 23
S232
R
C
L
L
D
N
S
S
G
F
L
A
M
N
F
Site 24
Y245
N
F
Q
G
K
L
K
Y
L
H
G
Q
K
K
K
Site 25
S257
K
K
K
G
K
D
G
S
I
L
P
P
Q
L
A
Site 26
S276
A
T
P
L
Q
P
P
S
I
L
E
I
R
T
K
Site 27
T296
T
K
H
K
L
D
F
T
P
I
G
C
D
A
K
Site 28
S320
A
E
L
C
T
R
G
S
G
Y
Q
F
I
H
A
Site 29
Y322
L
C
T
R
G
S
G
Y
Q
F
I
H
A
A
D
Site 30
Y371
Q
S
N
A
R
L
L
Y
K
N
G
R
P
D
Y
Site 31
Y378
Y
K
N
G
R
P
D
Y
I
I
V
T
Q
R
P
Site 32
T382
R
P
D
Y
I
I
V
T
Q
R
P
L
T
D
E
Site 33
T387
I
V
T
Q
R
P
L
T
D
E
E
G
T
E
H
Site 34
T400
E
H
L
R
K
R
N
T
K
L
P
F
M
F
T
Site 35
Y414
T
T
G
E
A
V
L
Y
E
A
T
N
P
F
P
Site 36
T435
P
L
R
T
K
N
G
T
S
G
K
D
S
A
T
Site 37
S436
L
R
T
K
N
G
T
S
G
K
D
S
A
T
T
Site 38
S440
N
G
T
S
G
K
D
S
A
T
T
S
T
L
S
Site 39
T442
T
S
G
K
D
S
A
T
T
S
T
L
S
K
D
Site 40
S444
G
K
D
S
A
T
T
S
T
L
S
K
D
S
L
Site 41
T445
K
D
S
A
T
T
S
T
L
S
K
D
S
L
N
Site 42
S447
S
A
T
T
S
T
L
S
K
D
S
L
N
P
S
Site 43
S450
T
S
T
L
S
K
D
S
L
N
P
S
S
L
L
Site 44
S454
S
K
D
S
L
N
P
S
S
L
L
A
A
M
M
Site 45
S455
K
D
S
L
N
P
S
S
L
L
A
A
M
M
Q
Site 46
Y468
M
Q
Q
D
E
S
I
Y
L
Y
P
A
S
S
T
Site 47
Y470
Q
D
E
S
I
Y
L
Y
P
A
S
S
T
S
S
Site 48
S473
S
I
Y
L
Y
P
A
S
S
T
S
S
T
A
P
Site 49
S477
Y
P
A
S
S
T
S
S
T
A
P
F
E
N
N
Site 50
T478
P
A
S
S
T
S
S
T
A
P
F
E
N
N
F
Site 51
S522
D
Q
P
Q
D
V
N
S
F
A
G
G
H
P
G
Site 52
S534
H
P
G
L
F
Q
D
S
K
N
S
D
L
Y
S
Site 53
Y540
D
S
K
N
S
D
L
Y
S
I
M
K
N
L
G
Site 54
S541
S
K
N
S
D
L
Y
S
I
M
K
N
L
G
I
Site 55
S567
K
F
F
R
N
D
F
S
G
E
V
D
F
R
D
Site 56
T578
D
F
R
D
I
D
L
T
D
E
I
L
T
Y
V
Site 57
Y584
L
T
D
E
I
L
T
Y
V
Q
D
S
L
S
K
Site 58
S590
T
Y
V
Q
D
S
L
S
K
S
P
F
I
P
S
Site 59
S592
V
Q
D
S
L
S
K
S
P
F
I
P
S
D
Y
Site 60
S597
S
K
S
P
F
I
P
S
D
Y
Q
Q
Q
Q
S
Site 61
Y599
S
P
F
I
P
S
D
Y
Q
Q
Q
Q
S
L
A
Site 62
S604
S
D
Y
Q
Q
Q
Q
S
L
A
L
N
S
S
C
Site 63
S610
Q
S
L
A
L
N
S
S
C
M
V
Q
E
H
L
Site 64
S682
F
T
D
L
H
G
I
S
Q
E
F
P
Y
K
S
Site 65
Y687
G
I
S
Q
E
F
P
Y
K
S
E
M
D
S
M
Site 66
S689
S
Q
E
F
P
Y
K
S
E
M
D
S
M
P
Y
Site 67
Y696
S
E
M
D
S
M
P
Y
T
Q
N
F
I
S
C
Site 68
S712
Q
P
V
L
P
Q
H
S
K
C
T
E
L
D
Y
Site 69
Y719
S
K
C
T
E
L
D
Y
P
M
G
S
F
E
P
Site 70
S723
E
L
D
Y
P
M
G
S
F
E
P
S
P
Y
P
Site 71
S727
P
M
G
S
F
E
P
S
P
Y
P
T
T
S
S
Site 72
Y729
G
S
F
E
P
S
P
Y
P
T
T
S
S
L
E
Site 73
T731
F
E
P
S
P
Y
P
T
T
S
S
L
E
D
F
Site 74
S734
S
P
Y
P
T
T
S
S
L
E
D
F
V
T
C
Site 75
T740
S
S
L
E
D
F
V
T
C
L
Q
L
P
E
N
Site 76
S756
K
H
G
L
N
P
Q
S
A
I
I
T
P
Q
T
Site 77
T760
N
P
Q
S
A
I
I
T
P
Q
T
C
Y
A
G
Site 78
Y772
Y
A
G
A
V
S
M
Y
Q
C
Q
P
E
P
Q
Site 79
Y788
T
H
V
G
Q
M
Q
Y
N
P
V
L
P
G
Q
Site 80
Y811
N
G
V
L
N
E
T
Y
P
A
E
L
N
N
I
Site 81
T843
A
R
P
F
P
D
L
T
S
S
G
F
L
_
_
Site 82
S844
R
P
F
P
D
L
T
S
S
G
F
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation