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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PGM1
Full Name:
Phosphoglucomutase-1
Alias:
EC 5.4.2.2; Glucose phosphomutase; PGM; PGMU; Phosphoglucomutase
Type:
Carbohydrate Metabolism - galactose; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - pentose phosphate pathway; EC 5.4.2.2; Carbohydrate Metabolism - starch and sucrose; Isomerase; Carbohydrate Metabolism - glycolysis and gluconeogenesis
Mass (Da):
61449
Number AA:
562
UniProt ID:
P36871
International Prot ID:
IPI00217872
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0000287
GO:0004614
PhosphoSite+
KinaseNET
Biological Process:
GO:0006006
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
V
T
V
K
T
Q
A
Y
Q
D
Q
K
P
G
T
Site 2
T19
Y
Q
D
Q
K
P
G
T
S
G
L
R
K
R
V
Site 3
S20
Q
D
Q
K
P
G
T
S
G
L
R
K
R
V
K
Site 4
Y35
V
F
Q
S
S
A
N
Y
A
E
N
F
I
Q
S
Site 5
T46
F
I
Q
S
I
I
S
T
V
E
P
A
Q
R
Q
Site 6
T56
P
A
Q
R
Q
E
A
T
L
V
V
G
G
D
G
Site 7
Y66
V
G
G
D
G
R
F
Y
M
K
E
A
I
Q
L
Site 8
T115
A
I
G
G
I
I
L
T
A
S
H
N
P
G
G
Site 9
S117
G
G
I
I
L
T
A
S
H
N
P
G
G
P
N
Site 10
S134
F
G
I
K
F
N
I
S
N
G
G
P
A
P
E
Site 11
T185
E
N
K
F
K
P
F
T
V
E
I
V
D
S
V
Site 12
Y195
I
V
D
S
V
E
A
Y
A
T
M
L
R
S
I
Site 13
T197
D
S
V
E
A
Y
A
T
M
L
R
S
I
F
D
Site 14
S213
S
A
L
K
E
L
L
S
G
P
N
R
L
K
I
Site 15
Y232
M
H
G
V
V
G
P
Y
V
K
K
I
L
C
E
Site 16
S278
D
L
V
E
T
M
K
S
G
E
H
D
F
G
A
Site 17
Y322
A
N
I
F
S
I
P
Y
F
Q
Q
T
G
V
R
Site 18
S338
F
A
R
S
M
P
T
S
G
A
L
D
R
V
A
Site 19
S346
G
A
L
D
R
V
A
S
A
T
K
I
A
L
Y
Site 20
Y353
S
A
T
K
I
A
L
Y
E
T
P
T
G
W
K
Site 21
T355
T
K
I
A
L
Y
E
T
P
T
G
W
K
F
F
Site 22
S369
F
G
N
L
M
D
A
S
K
L
S
L
C
G
E
Site 23
S378
L
S
L
C
G
E
E
S
F
G
T
G
S
D
H
Site 24
T381
C
G
E
E
S
F
G
T
G
S
D
H
I
R
E
Site 25
S383
E
E
S
F
G
T
G
S
D
H
I
R
E
K
D
Site 26
T404
A
W
L
S
I
L
A
T
R
K
Q
S
V
E
D
Site 27
S408
I
L
A
T
R
K
Q
S
V
E
D
I
L
K
D
Site 28
Y420
L
K
D
H
W
Q
K
Y
G
R
N
F
F
T
R
Site 29
Y428
G
R
N
F
F
T
R
Y
D
Y
E
E
V
E
A
Site 30
Y430
N
F
F
T
R
Y
D
Y
E
E
V
E
A
E
G
Site 31
S453
E
A
L
M
F
D
R
S
F
V
G
K
Q
F
S
Site 32
S460
S
F
V
G
K
Q
F
S
A
N
D
K
V
Y
T
Site 33
Y466
F
S
A
N
D
K
V
Y
T
V
E
K
A
D
N
Site 34
T467
S
A
N
D
K
V
Y
T
V
E
K
A
D
N
F
Site 35
Y476
E
K
A
D
N
F
E
Y
S
D
P
V
D
G
S
Site 36
S477
K
A
D
N
F
E
Y
S
D
P
V
D
G
S
I
Site 37
S483
Y
S
D
P
V
D
G
S
I
S
R
N
Q
G
L
Site 38
S485
D
P
V
D
G
S
I
S
R
N
Q
G
L
R
L
Site 39
S505
S
R
I
V
F
R
L
S
G
T
G
S
A
G
A
Site 40
T507
I
V
F
R
L
S
G
T
G
S
A
G
A
T
I
Site 41
S509
F
R
L
S
G
T
G
S
A
G
A
T
I
R
L
Site 42
T513
G
T
G
S
A
G
A
T
I
R
L
Y
I
D
S
Site 43
Y517
A
G
A
T
I
R
L
Y
I
D
S
Y
E
K
D
Site 44
S520
T
I
R
L
Y
I
D
S
Y
E
K
D
V
A
K
Site 45
Y521
I
R
L
Y
I
D
S
Y
E
K
D
V
A
K
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation