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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ERM
Full Name:
ETS translocation variant 5
Alias:
Ets-related protein ERM
Type:
Transcription protein
Mass (Da):
57838
Number AA:
510
UniProt ID:
P41161
International Prot ID:
IPI00218204
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0010843
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0034599
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y5
_
_
_
M
D
G
F
Y
D
Q
Q
V
P
F
M
Site 2
S17
P
F
M
V
P
G
K
S
R
S
E
E
C
R
G
Site 3
S19
M
V
P
G
K
S
R
S
E
E
C
R
G
R
P
Site 4
T37
R
K
R
K
F
L
D
T
D
L
A
H
D
S
E
Site 5
S43
D
T
D
L
A
H
D
S
E
E
L
F
Q
D
L
Site 6
S51
E
E
L
F
Q
D
L
S
Q
L
Q
E
A
W
L
Site 7
S75
Q
F
V
P
D
F
Q
S
D
N
L
V
L
H
A
Site 8
S94
K
I
K
R
E
L
H
S
P
S
S
E
L
S
S
Site 9
S96
K
R
E
L
H
S
P
S
S
E
L
S
S
C
S
Site 10
S97
R
E
L
H
S
P
S
S
E
L
S
S
C
S
H
Site 11
S100
H
S
P
S
S
E
L
S
S
C
S
H
E
Q
A
Site 12
S101
S
P
S
S
E
L
S
S
C
S
H
E
Q
A
L
Site 13
S103
S
S
E
L
S
S
C
S
H
E
Q
A
L
G
A
Site 14
Y118
N
Y
G
E
K
C
L
Y
N
Y
C
A
Y
D
R
Site 15
Y120
G
E
K
C
L
Y
N
Y
C
A
Y
D
R
K
P
Site 16
Y123
C
L
Y
N
Y
C
A
Y
D
R
K
P
P
S
G
Site 17
S129
A
Y
D
R
K
P
P
S
G
F
K
P
L
T
P
Site 18
T135
P
S
G
F
K
P
L
T
P
P
T
T
P
L
S
Site 19
T138
F
K
P
L
T
P
P
T
T
P
L
S
P
T
H
Site 20
T139
K
P
L
T
P
P
T
T
P
L
S
P
T
H
Q
Site 21
S142
T
P
P
T
T
P
L
S
P
T
H
Q
N
P
L
Site 22
T156
L
F
P
P
P
Q
A
T
L
P
T
S
G
H
A
Site 23
S160
P
Q
A
T
L
P
T
S
G
H
A
P
A
A
G
Site 24
S180
G
P
A
P
A
P
H
S
L
P
E
P
G
P
Q
Site 25
T190
E
P
G
P
Q
Q
Q
T
F
A
V
P
R
P
P
Site 26
Y212
K
M
M
P
E
N
Q
Y
P
S
E
Q
R
F
Q
Site 27
S214
M
P
E
N
Q
Y
P
S
E
Q
R
F
Q
R
Q
Site 28
S223
Q
R
F
Q
R
Q
L
S
E
P
C
H
P
F
P
Site 29
S242
V
P
G
D
N
R
P
S
Y
H
R
Q
M
S
E
Site 30
Y243
P
G
D
N
R
P
S
Y
H
R
Q
M
S
E
P
Site 31
S248
P
S
Y
H
R
Q
M
S
E
P
I
V
P
A
A
Site 32
Y266
P
Q
G
F
K
Q
E
Y
H
D
P
L
Y
E
H
Site 33
Y271
Q
E
Y
H
D
P
L
Y
E
H
G
V
P
G
M
Site 34
S288
P
P
A
H
G
F
Q
S
P
M
G
I
K
Q
E
Site 35
Y299
I
K
Q
E
P
R
D
Y
C
V
D
S
E
V
P
Site 36
S303
P
R
D
Y
C
V
D
S
E
V
P
N
C
Q
S
Site 37
S310
S
E
V
P
N
C
Q
S
S
Y
M
R
G
G
Y
Site 38
Y312
V
P
N
C
Q
S
S
Y
M
R
G
G
Y
F
S
Site 39
Y317
S
S
Y
M
R
G
G
Y
F
S
S
S
H
E
G
Site 40
S319
Y
M
R
G
G
Y
F
S
S
S
H
E
G
F
S
Site 41
S320
M
R
G
G
Y
F
S
S
S
H
E
G
F
S
Y
Site 42
S321
R
G
G
Y
F
S
S
S
H
E
G
F
S
Y
E
Site 43
S326
S
S
S
H
E
G
F
S
Y
E
K
D
P
R
L
Site 44
Y327
S
S
H
E
G
F
S
Y
E
K
D
P
R
L
Y
Site 45
Y334
Y
E
K
D
P
R
L
Y
F
D
D
T
C
V
V
Site 46
T338
P
R
L
Y
F
D
D
T
C
V
V
P
E
R
L
Site 47
T354
G
K
V
K
Q
E
P
T
M
Y
R
E
G
P
P
Site 48
Y356
V
K
Q
E
P
T
M
Y
R
E
G
P
P
Y
Q
Site 49
Y362
M
Y
R
E
G
P
P
Y
Q
R
R
G
S
L
Q
Site 50
S367
P
P
Y
Q
R
R
G
S
L
Q
L
W
Q
F
L
Site 51
Y419
K
N
R
P
A
M
N
Y
D
K
L
S
R
S
L
Site 52
S425
N
Y
D
K
L
S
R
S
L
R
Y
Y
Y
E
K
Site 53
Y429
L
S
R
S
L
R
Y
Y
Y
E
K
G
I
M
Q
Site 54
Y430
S
R
S
L
R
Y
Y
Y
E
K
G
I
M
Q
K
Site 55
Y443
Q
K
V
A
G
E
R
Y
V
Y
K
F
V
C
D
Site 56
Y445
V
A
G
E
R
Y
V
Y
K
F
V
C
D
P
D
Site 57
S471
R
P
F
L
K
A
E
S
E
C
H
L
S
E
E
Site 58
S476
A
E
S
E
C
H
L
S
E
E
D
T
L
P
L
Site 59
T480
C
H
L
S
E
E
D
T
L
P
L
T
H
F
E
Site 60
T484
E
E
D
T
L
P
L
T
H
F
E
D
S
P
A
Site 61
S489
P
L
T
H
F
E
D
S
P
A
Y
L
L
D
M
Site 62
Y492
H
F
E
D
S
P
A
Y
L
L
D
M
D
R
C
Site 63
S500
L
L
D
M
D
R
C
S
S
L
P
Y
A
E
G
Site 64
S501
L
D
M
D
R
C
S
S
L
P
Y
A
E
G
F
Site 65
Y504
D
R
C
S
S
L
P
Y
A
E
G
F
A
Y
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation