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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GluR1
Full Name:
Glutamate receptor 1
Alias:
AMPA-selective glutamate receptor 1; GLR1; GLUH1; GLUR1; GluR-1; GLURA; GluR-A; GluR-K1; Glutamate receptor ionotropic, AMPA 1; Glutamate receptor, ionotropic, AMPA 1; GRIA1
Type:
Channel, calcium; Channel, ligand-gated
Mass (Da):
101506
Number AA:
906
UniProt ID:
P42261
International Prot ID:
IPI00030880
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0030666
GO:0005783
Uniprot
OncoNet
Molecular Function:
GO:0005234
GO:0015277
PhosphoSite+
KinaseNET
Biological Process:
GO:0006811
GO:0007165
GO:0007268
Phosida
TranscriptoNet
STRING
Kinexus Products
AMPA selective glutamate receptor 1 pan-specific antibody AB-NN263-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN263-1#GluR1(I850-N862, human) peptide - Powder PE-01AMJ95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01AMJ95
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S36
G
L
F
P
N
Q
Q
S
Q
E
H
A
A
F
R
Site 2
S47
A
A
F
R
F
A
L
S
Q
L
T
E
P
P
K
Site 3
T50
R
F
A
L
S
Q
L
T
E
P
P
K
L
L
P
Site 4
Y72
S
D
S
F
E
M
T
Y
R
F
C
S
Q
F
S
Site 5
T93
F
G
F
Y
E
R
R
T
V
N
M
L
T
S
F
Site 6
S118
P
S
F
P
V
D
T
S
N
Q
F
V
L
Q
L
Site 7
Y149
W
Q
K
F
V
Y
I
Y
D
A
D
R
G
L
S
Site 8
S156
Y
D
A
D
R
G
L
S
V
L
Q
K
V
L
D
Site 9
Y226
L
E
K
N
G
I
G
Y
H
Y
I
L
A
N
L
Site 10
Y228
K
N
G
I
G
Y
H
Y
I
L
A
N
L
G
F
Site 11
Y258
T
G
F
Q
L
V
N
Y
T
D
T
I
P
A
K
Site 12
T279
N
S
D
A
R
D
H
T
R
V
D
W
K
R
P
Site 13
Y288
V
D
W
K
R
P
K
Y
T
S
A
L
T
Y
D
Site 14
S290
W
K
R
P
K
Y
T
S
A
L
T
Y
D
G
V
Site 15
Y294
K
Y
T
S
A
L
T
Y
D
G
V
K
V
M
A
Site 16
S306
V
M
A
E
A
F
Q
S
L
R
R
Q
R
I
D
Site 17
S315
R
R
Q
R
I
D
I
S
R
R
G
N
A
G
D
Site 18
T350
Q
V
R
F
E
G
L
T
G
N
V
Q
F
N
E
Site 19
T362
F
N
E
K
G
R
R
T
N
Y
T
L
H
V
I
Site 20
Y364
E
K
G
R
R
T
N
Y
T
L
H
V
I
E
M
Site 21
T365
K
G
R
R
T
N
Y
T
L
H
V
I
E
M
K
Site 22
Y381
D
G
I
R
K
I
G
Y
W
N
E
D
D
K
F
Site 23
S402
A
Q
A
G
G
D
N
S
S
V
Q
N
R
T
Y
Site 24
S403
Q
A
G
G
D
N
S
S
V
Q
N
R
T
Y
I
Site 25
Y409
S
S
V
Q
N
R
T
Y
I
V
T
T
I
L
E
Site 26
T412
Q
N
R
T
Y
I
V
T
T
I
L
E
D
P
Y
Site 27
Y419
T
T
I
L
E
D
P
Y
V
M
L
K
K
N
A
Site 28
Y435
Q
F
E
G
N
D
R
Y
E
G
Y
C
V
E
L
Site 29
S460
S
Y
R
L
E
I
V
S
D
G
K
Y
G
A
R
Site 30
Y464
E
I
V
S
D
G
K
Y
G
A
R
D
P
D
T
Site 31
S506
R
E
E
V
I
D
F
S
K
P
F
M
S
L
G
Site 32
S524
M
I
K
K
P
Q
K
S
K
P
G
V
F
S
F
Site 33
S530
K
S
K
P
G
V
F
S
F
L
D
P
L
A
Y
Site 34
Y537
S
F
L
D
P
L
A
Y
E
I
W
M
C
I
V
Site 35
S561
L
F
L
V
S
R
F
S
P
Y
E
W
H
S
E
Site 36
Y563
L
V
S
R
F
S
P
Y
E
W
H
S
E
E
F
Site 37
S567
F
S
P
Y
E
W
H
S
E
E
F
E
E
G
R
Site 38
T577
F
E
E
G
R
D
Q
T
T
S
D
Q
S
N
E
Site 39
T578
E
E
G
R
D
Q
T
T
S
D
Q
S
N
E
F
Site 40
S579
E
G
R
D
Q
T
T
S
D
Q
S
N
E
F
G
Site 41
S606
M
Q
Q
G
C
D
I
S
P
R
S
L
S
G
R
Site 42
S609
G
C
D
I
S
P
R
S
L
S
G
R
I
V
G
Site 43
S645
L
T
V
E
R
M
V
S
P
I
E
S
A
E
D
Site 44
S649
R
M
V
S
P
I
E
S
A
E
D
L
A
K
Q
Site 45
S668
Y
G
T
L
E
A
G
S
T
K
E
F
F
R
R
Site 46
T669
G
T
L
E
A
G
S
T
K
E
F
F
R
R
S
Site 47
S676
T
K
E
F
F
R
R
S
K
I
A
V
F
E
K
Site 48
T686
A
V
F
E
K
M
W
T
Y
M
K
S
A
E
P
Site 49
S694
Y
M
K
S
A
E
P
S
V
F
V
R
T
T
E
Site 50
S710
G
M
I
R
V
R
K
S
K
G
K
Y
A
Y
L
Site 51
Y714
V
R
K
S
K
G
K
Y
A
Y
L
L
E
S
T
Site 52
Y716
K
S
K
G
K
Y
A
Y
L
L
E
S
T
M
N
Site 53
T734
E
Q
R
K
P
C
D
T
M
K
V
G
G
N
L
Site 54
S743
K
V
G
G
N
L
D
S
K
G
Y
G
I
A
T
Site 55
T750
S
K
G
Y
G
I
A
T
P
K
G
S
A
L
R
Site 56
S754
G
I
A
T
P
K
G
S
A
L
R
N
P
V
N
Site 57
Y782
K
L
K
N
K
W
W
Y
D
K
G
E
C
G
S
Site 58
S794
C
G
S
G
G
G
D
S
K
D
K
T
S
A
L
Site 59
T798
G
G
D
S
K
D
K
T
S
A
L
S
L
S
N
Site 60
S799
G
D
S
K
D
K
T
S
A
L
S
L
S
N
V
Site 61
S802
K
D
K
T
S
A
L
S
L
S
N
V
A
G
V
Site 62
Y830
V
A
L
I
E
F
C
Y
K
S
R
S
E
S
K
Site 63
S832
L
I
E
F
C
Y
K
S
R
S
E
S
K
R
M
Site 64
S834
E
F
C
Y
K
S
R
S
E
S
K
R
M
K
G
Site 65
S836
C
Y
K
S
R
S
E
S
K
R
M
K
G
F
C
Site 66
S849
F
C
L
I
P
Q
Q
S
I
N
E
A
I
R
T
Site 67
T856
S
I
N
E
A
I
R
T
S
T
L
P
R
N
S
Site 68
S857
I
N
E
A
I
R
T
S
T
L
P
R
N
S
G
Site 69
T858
N
E
A
I
R
T
S
T
L
P
R
N
S
G
A
Site 70
S863
T
S
T
L
P
R
N
S
G
A
G
A
S
S
G
Site 71
S868
R
N
S
G
A
G
A
S
S
G
G
S
G
E
N
Site 72
S869
N
S
G
A
G
A
S
S
G
G
S
G
E
N
G
Site 73
S872
A
G
A
S
S
G
G
S
G
E
N
G
R
V
V
Site 74
S880
G
E
N
G
R
V
V
S
H
D
F
P
K
S
M
Site 75
S889
D
F
P
K
S
M
Q
S
I
P
C
M
S
H
S
Site 76
S894
M
Q
S
I
P
C
M
S
H
S
S
G
M
P
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation