KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ARRB1
Full Name:
Beta-arrestin-1
Alias:
ARR1; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Arrestin, beta 1
Type:
Adapter/scaffold protein
Mass (Da):
47066
Number AA:
418
UniProt ID:
P49407
International Prot ID:
IPI00293857
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005624
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004857
GO:0005515
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0016044
GO:0006892
GO:0007600
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
T
R
V
F
K
K
A
S
P
N
G
K
L
T
V
Site 2
T19
A
S
P
N
G
K
L
T
V
Y
L
G
K
R
D
Site 3
Y21
P
N
G
K
L
T
V
Y
L
G
K
R
D
F
V
Site 4
Y47
V
V
L
V
D
P
E
Y
L
K
E
R
R
V
Y
Site 5
Y54
Y
L
K
E
R
R
V
Y
V
T
L
T
C
A
F
Site 6
T56
K
E
R
R
V
Y
V
T
L
T
C
A
F
R
Y
Site 7
T58
R
R
V
Y
V
T
L
T
C
A
F
R
Y
G
R
Site 8
S86
L
F
V
A
N
V
Q
S
F
P
P
A
P
E
D
Site 9
T98
P
E
D
K
K
P
L
T
R
L
Q
E
R
L
I
Site 10
Y113
K
K
L
G
E
H
A
Y
P
F
T
F
E
I
P
Site 11
T116
G
E
H
A
Y
P
F
T
F
E
I
P
P
N
L
Site 12
T128
P
N
L
P
C
S
V
T
L
Q
P
G
P
E
D
Site 13
Y144
G
K
A
C
G
V
D
Y
E
V
K
A
F
C
A
Site 14
S163
E
K
I
H
K
R
N
S
V
R
L
V
I
R
K
Site 15
Y173
L
V
I
R
K
V
Q
Y
A
P
E
R
P
G
P
Site 16
T186
G
P
Q
P
T
A
E
T
T
R
Q
F
L
M
S
Site 17
S193
T
T
R
Q
F
L
M
S
D
K
P
L
H
L
E
Site 18
S202
K
P
L
H
L
E
A
S
L
D
K
E
I
Y
Y
Site 19
Y208
A
S
L
D
K
E
I
Y
Y
H
G
E
P
I
S
Site 20
Y209
S
L
D
K
E
I
Y
Y
H
G
E
P
I
S
V
Site 21
T227
V
T
N
N
T
N
K
T
V
K
K
I
K
I
S
Site 22
S234
T
V
K
K
I
K
I
S
V
R
Q
Y
A
D
I
Site 23
T261
A
M
E
E
A
D
D
T
V
A
P
S
S
T
F
Site 24
S266
D
D
T
V
A
P
S
S
T
F
C
K
V
Y
T
Site 25
T298
G
K
L
K
H
E
D
T
N
L
A
S
S
T
L
Site 26
T304
D
T
N
L
A
S
S
T
L
L
R
E
G
A
N
Site 27
T370
R
E
V
P
E
N
E
T
P
V
D
T
N
L
I
Site 28
T381
T
N
L
I
E
L
D
T
N
D
D
D
I
V
F
Site 29
T410
K
E
E
E
E
D
G
T
G
S
P
Q
L
N
N
Site 30
S412
E
E
E
D
G
T
G
S
P
Q
L
N
N
R
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation