PhosphoNET

           
Protein Info 
   
Short Name:  EMD
Full Name:  Emerin
Alias:  EDMD; Emerin (Emery-Dreifuss muscular dystrophy), isoform CRAb; LEM domain containing 5; LEMD5; STA
Type:  Cytoskeletal protein
Mass (Da):  28994
Number AA:  254
UniProt ID:  P50402
International Prot ID:  IPI00032003
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005783  GO:0016021  GO:0005640 Uniprot OncoNet
Molecular Function:  GO:0003779  GO:0048487   PhosphoSite+ KinaseNET
Biological Process:  GO:0006936  GO:0007517   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y4____MDNYADLSDTE
Site 2S8MDNYADLSDTELTTL
Site 3T10NYADLSDTELTTLLR
Site 4Y19LTTLLRRYNIPHGPV
Site 5S29PHGPVVGSTRRLYEK
Site 6T30HGPVVGSTRRLYEKK
Site 7Y34VGSTRRLYEKKIFEY
Site 8Y41YEKKIFEYETQRRRL
Site 9T43KKIFEYETQRRRLSP
Site 10S49ETQRRRLSPPSSSAA
Site 11S52RRRLSPPSSSAASSY
Site 12S53RRLSPPSSSAASSYS
Site 13S54RLSPPSSSAASSYSF
Site 14S57PPSSSAASSYSFSDL
Site 15S58PSSSAASSYSFSDLN
Site 16Y59SSSAASSYSFSDLNS
Site 17S60SSAASSYSFSDLNST
Site 18S62AASSYSFSDLNSTRG
Site 19S66YSFSDLNSTRGDADM
Site 20T67SFSDLNSTRGDADMY
Site 21Y74TRGDADMYDLPKKED
Site 22Y85KKEDALLYQSKGYND
Site 23S87EDALLYQSKGYNDDY
Site 24Y90LLYQSKGYNDDYYEE
Site 25Y94SKGYNDDYYEESYFT
Site 26Y95KGYNDDYYEESYFTT
Site 27S98NDDYYEESYFTTRTY
Site 28Y99DDYYEESYFTTRTYG
Site 29T101YYEESYFTTRTYGEP
Site 30T104ESYFTTRTYGEPESA
Site 31Y105SYFTTRTYGEPESAG
Site 32S110RTYGEPESAGPSRAV
Site 33S114EPESAGPSRAVRQSV
Site 34S120PSRAVRQSVTSFPDA
Site 35T122RAVRQSVTSFPDADA
Site 36S123AVRQSVTSFPDADAF
Site 37S141VHDDDLLSSSEEECK
Site 38S142HDDDLLSSSEEECKD
Site 39S143DDDLLSSSEEECKDR
Site 40Y155KDRERPMYGRDSAYQ
Site 41S159RPMYGRDSAYQSITH
Site 42Y161MYGRDSAYQSITHYR
Site 43S163GRDSAYQSITHYRPV
Site 44T165DSAYQSITHYRPVSA
Site 45Y167AYQSITHYRPVSASR
Site 46S171ITHYRPVSASRSSLD
Site 47S173HYRPVSASRSSLDLS
Site 48S175RPVSASRSSLDLSYY
Site 49S176PVSASRSSLDLSYYP
Site 50S180SRSSLDLSYYPTSSS
Site 51Y181RSSLDLSYYPTSSST
Site 52Y182SSLDLSYYPTSSSTS
Site 53T184LDLSYYPTSSSTSFM
Site 54S185DLSYYPTSSSTSFMS
Site 55S186LSYYPTSSSTSFMSS
Site 56S187SYYPTSSSTSFMSSS
Site 57T188YYPTSSSTSFMSSSS
Site 58S189YPTSSSTSFMSSSSS
Site 59S192SSSTSFMSSSSSSSS
Site 60S193SSTSFMSSSSSSSSW
Site 61S194STSFMSSSSSSSSWL
Site 62S195TSFMSSSSSSSSWLT
Site 63S196SFMSSSSSSSSWLTR
Site 64S197FMSSSSSSSSWLTRR
Site 65S198MSSSSSSSSWLTRRA
Site 66S199SSSSSSSSWLTRRAI
Site 67T202SSSSSWLTRRAIRPE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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