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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCR5
Full Name:
C-C chemokine receptor type 5
Alias:
C-C CKR-5; CC-CKR-5; CCR-5; CD195; CD195 antigen; Chemokine (C-C motif) receptor 5; CHEMR13; CKR5; CKR-5; CMKBR5; HIV-1 fusion co-receptor; MIP-1 alpha receptor
Type:
7TM receptor, G protein-coupled
Mass (Da):
40524
Number AA:
352
UniProt ID:
P51681
International Prot ID:
IPI00743929
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005768
GO:0009897
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0016493
GO:0003779
GO:0015026
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
GO:0007267
GO:0006968
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
Y
Q
V
S
S
P
I
Y
D
I
N
Y
Y
T
S
Site 2
Y14
S
P
I
Y
D
I
N
Y
Y
T
S
E
P
C
Q
Site 3
Y15
P
I
Y
D
I
N
Y
Y
T
S
E
P
C
Q
K
Site 4
Y127
I
L
L
T
I
D
R
Y
L
A
V
V
H
A
V
Site 5
S169
P
G
I
I
F
T
R
S
Q
K
E
G
L
H
Y
Site 6
Y176
S
Q
K
E
G
L
H
Y
T
C
S
S
H
F
P
Site 7
T177
Q
K
E
G
L
H
Y
T
C
S
S
H
F
P
Y
Site 8
T220
C
Y
S
G
I
L
K
T
L
L
R
C
R
N
E
Site 9
S270
F
F
G
L
N
N
C
S
S
S
N
R
L
D
Q
Site 10
S271
F
G
L
N
N
C
S
S
S
N
R
L
D
Q
A
Site 11
S272
G
L
N
N
C
S
S
S
N
R
L
D
Q
A
M
Site 12
Y297
C
C
I
N
P
I
I
Y
A
F
V
G
E
K
F
Site 13
Y307
V
G
E
K
F
R
N
Y
L
L
V
F
F
Q
K
Site 14
S336
Q
E
A
P
E
R
A
S
S
V
Y
T
R
S
T
Site 15
S337
E
A
P
E
R
A
S
S
V
Y
T
R
S
T
G
Site 16
Y339
P
E
R
A
S
S
V
Y
T
R
S
T
G
E
Q
Site 17
S342
A
S
S
V
Y
T
R
S
T
G
E
Q
E
I
S
Site 18
T343
S
S
V
Y
T
R
S
T
G
E
Q
E
I
S
V
Site 19
S349
S
T
G
E
Q
E
I
S
V
G
L
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation