PhosphoNET

           
Protein Info 
   
Short Name:  ARHGDIB
Full Name:  Rho GDP-dissociation inhibitor 2
Alias:  D4; GDIA2; GDID4; GDIR2; GDIS; Ly-GDI; RAP1GN1; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; Rho-GDI beta; RhoGDI2
Type:  G protein regulator, misc.
Mass (Da):  22988
Number AA:  201
UniProt ID:  P52566
International Prot ID:  IPI00003817
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016023  GO:0005856   Uniprot OncoNet
Molecular Function:  GO:0005096  GO:0005094   PhosphoSite+ KinaseNET
Biological Process:  GO:0007266  GO:0030036  GO:0006928 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S20DDDDELDSKLNYKPP
Site 2Y24ELDSKLNYKPPPQKS
Site 3S31YKPPPQKSLKELQEM
Site 4S44EMDKDDESLIKYKKT
Site 5Y48DDESLIKYKKTLLGD
Site 6T51SLIKYKKTLLGDGPV
Site 7T60LGDGPVVTDPKAPNV
Site 8T84ESAPGPITMDLTGDL
Site 9T98LEALKKETIVLKEGS
Site 10Y107VLKEGSEYRVKIHFK
Site 11Y125DIVSGLKYVQHTYRT
Site 12Y130LKYVQHTYRTGVKVD
Site 13S145KATFMVGSYGPRPEE
Site 14Y146ATFMVGSYGPRPEEY
Site 15Y153YGPRPEEYEFLTPVE
Site 16T157PEEYEFLTPVEEAPK
Site 17T171KGMLARGTYHNKSFF
Site 18Y172GMLARGTYHNKSFFT
Site 19S176RGTYHNKSFFTDDDK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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