PhosphoNET

           
Protein Info 
   
Short Name:  TFIIA
Full Name:  Transcription initiation factor IIA subunit 1
Alias:  General transcription factor IIA subunit 1;TFIIAL;Transcription initiation factor TFIIA 42 kDa subunit;TFIIA p35 subunit;TFIIA p19 subunit
Type:  Transcription regulation protein
Mass (Da):  41514
Number AA:  376
UniProt ID:  P52655
International Prot ID:  IPI00004350
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634  GO:0005672 Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0017025  GO:0016251 PhosphoSite+ KinaseNET
Biological Process:  GO:0006368  GO:0032568  GO:0045449 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y14TNTVPKLYRSVIEDV
Site 2T44QVLMELKTLWENKLM
Site 3S110QQVLIPASQQATAPQ
Site 4T157TPVQQILTNSGQLLQ
Site 5T217PGGISPQTGVIIQPQ
Site 6T265PQAQPAQTQAPLVLQ
Site 7T276LVLQVDGTGDTSSEE
Site 8S280VDGTGDTSSEEDEDE
Site 9S281DGTGDTSSEEDEDEE
Site 10Y291DEDEEEDYDDDEEED
Site 11S316VEEEPLNSEDDVSDE
Site 12S321LNSEDDVSDEEGQEL
Site 13T331EGQELFDTENVVVCQ
Site 14Y339ENVVVCQYDKIHRSK
Site 15Y365MNLNGRDYIFSKAIG
Site 16S368NGRDYIFSKAIGDAE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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