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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CAPZA1
Full Name:
F-actin-capping protein subunit alpha-1
Alias:
Cap Z; CAPPA1; CAPZ; CapZ alpha-1; CAZ1; CAZA1; F-actin capping protein alpha-1 subunit
Type:
Actin binding protein
Mass (Da):
32923
Number AA:
286
UniProt ID:
P52907
International Prot ID:
IPI00005969
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0008290
GO:0008290
GO:0015629
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0030036
GO:0051693
GO:0006928
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
D
F
D
D
R
V
S
D
E
E
K
V
R
I
Site 2
T63
Q
Y
N
M
D
Q
F
T
P
V
K
I
E
G
Y
Site 3
S95
L
D
P
R
N
K
I
S
F
K
F
D
H
L
R
Site 4
S106
D
H
L
R
K
E
A
S
D
P
Q
P
E
E
A
Site 5
S119
E
A
D
G
G
L
K
S
W
R
E
S
C
D
S
Site 6
S123
G
L
K
S
W
R
E
S
C
D
S
A
L
R
A
Site 7
S126
S
W
R
E
S
C
D
S
A
L
R
A
Y
V
K
Site 8
Y131
C
D
S
A
L
R
A
Y
V
K
D
H
Y
S
N
Site 9
Y136
R
A
Y
V
K
D
H
Y
S
N
G
F
C
T
V
Site 10
Y144
S
N
G
F
C
T
V
Y
A
K
T
I
D
G
Q
Site 11
T180
W
R
S
E
W
K
F
T
I
T
P
P
T
A
Q
Site 12
T182
S
E
W
K
F
T
I
T
P
P
T
A
Q
V
V
Site 13
Y198
V
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
Site 14
Y199
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
L
Site 15
S208
D
G
N
V
Q
L
V
S
H
K
D
V
Q
D
S
Site 16
S215
S
H
K
D
V
Q
D
S
L
T
V
S
N
E
A
Site 17
T217
K
D
V
Q
D
S
L
T
V
S
N
E
A
Q
T
Site 18
S219
V
Q
D
S
L
T
V
S
N
E
A
Q
T
A
K
Site 19
T249
A
I
S
E
N
Y
Q
T
M
S
D
T
T
F
K
Site 20
S251
S
E
N
Y
Q
T
M
S
D
T
T
F
K
A
L
Site 21
T253
N
Y
Q
T
M
S
D
T
T
F
K
A
L
R
R
Site 22
T265
L
R
R
Q
L
P
V
T
R
T
K
I
D
W
N
Site 23
Y277
D
W
N
K
I
L
S
Y
K
I
G
K
E
M
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation