PhosphoNET

           
Protein Info 
   
Short Name:  ATN1
Full Name:  Atrophin-1
Alias:  Atrophin 1; B37; D12S755E; Dentatorubral-pallidoluysian atrophy protein; DRPL
Type:  Ubiquitin conjugating system
Mass (Da):  124774
Number AA:  1185
UniProt ID:  P54259
International Prot ID:  IPI00477923
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0019904     PhosphoSite+ KinaseNET
Biological Process:  GO:0008219  GO:0007417   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9KTRQNKDSMSMRSGR
Site 2S11RQNKDSMSMRSGRKK
Site 3S14KDSMSMRSGRKKEAP
Site 4S29GPREELRSRGRASPG
Site 5S34LRSRGRASPGGVSTS
Site 6S39RASPGGVSTSSSDGK
Site 7S41SPGGVSTSSSDGKAE
Site 8S42PGGVSTSSSDGKAEK
Site 9S43GGVSTSSSDGKAEKS
Site 10S50SDGKAEKSRQTAKKA
Site 11T53KAEKSRQTAKKARVE
Site 12S63KARVEEASTPKVNKQ
Site 13T64ARVEEASTPKVNKQG
Site 14S73KVNKQGRSEEISESE
Site 15S77QGRSEEISESESEET
Site 16S79RSEEISESESEETNA
Site 17S81EEISESESEETNAPK
Site 18T84SESESEETNAPKKTK
Site 19T92NAPKKTKTEQELPRP
Site 20S101QELPRPQSPSDLDSL
Site 21S103LPRPQSPSDLDSLDG
Site 22S107QSPSDLDSLDGRSLN
Site 23S112LDSLDGRSLNDDGSS
Site 24S118RSLNDDGSSDPRDID
Site 25S119SLNDDGSSDPRDIDQ
Site 26S130DIDQDNRSTSPSIYS
Site 27T131IDQDNRSTSPSIYSP
Site 28S132DQDNRSTSPSIYSPG
Site 29S134DNRSTSPSIYSPGSV
Site 30Y136RSTSPSIYSPGSVEN
Site 31S137STSPSIYSPGSVEND
Site 32S140PSIYSPGSVENDSDS
Site 33S145PGSVENDSDSSSGLS
Site 34S147SVENDSDSSSGLSQG
Site 35S149ENDSDSSSGLSQGPA
Site 36S152SDSSSGLSQGPARPY
Site 37Y159SQGPARPYHPPPLFP
Site 38S168PPPLFPPSPQPPDST
Site 39S174PSPQPPDSTPRQPEA
Site 40T175SPQPPDSTPRQPEAS
Site 41S182TPRQPEASFEPHPSV
Site 42S188ASFEPHPSVTPTGYH
Site 43T190FEPHPSVTPTGYHAP
Site 44T192PHPSVTPTGYHAPME
Site 45Y194PSVTPTGYHAPMEPP
Site 46T202HAPMEPPTSRMFQAP
Site 47S203APMEPPTSRMFQAPP
Site 48Y220PPPHPQLYPGGTGGV
Site 49S229GGTGGVLSGPPMGPK
Site 50S242PKGGGAASSVGGPNG
Site 51S243KGGGAASSVGGPNGG
Site 52T257GKQHPPPTTPISVSS
Site 53T258KQHPPPTTPISVSSS
Site 54S261PPPTTPISVSSSGAS
Site 55S263PTTPISVSSSGASGA
Site 56S264TTPISVSSSGASGAP
Site 57S265TPISVSSSGASGAPP
Site 58S268SVSSSGASGAPPTKP
Site 59T273GASGAPPTKPPTTPV
Site 60T277APPTKPPTTPVGGGN
Site 61T278PPTKPPTTPVGGGNL
Site 62S287VGGGNLPSAPPPANF
Site 63T298PANFPHVTPNLPPPP
Site 64S314LRPLNNASASPPGLG
Site 65S316PLNNASASPPGLGAQ
Site 66S331PLPGHLPSPHAMGQG
Site 67T351PGPEKGPTLAPSPHS
Site 68S355KGPTLAPSPHSLPPA
Site 69S358TLAPSPHSLPPASSS
Site 70S363PHSLPPASSSAPAPP
Site 71S364HSLPPASSSAPAPPM
Site 72S365SLPPASSSAPAPPMR
Site 73Y375APPMRFPYSSSSSSS
Site 74S376PPMRFPYSSSSSSSA
Site 75S377PMRFPYSSSSSSSAA
Site 76S378MRFPYSSSSSSSAAA
Site 77S379RFPYSSSSSSSAAAS
Site 78S380FPYSSSSSSSAAASS
Site 79S381PYSSSSSSSAAASSS
Site 80S382YSSSSSSSAAASSSS
Site 81S386SSSSAAASSSSSSSS
Site 82S387SSSAAASSSSSSSSS
Site 83S388SSAAASSSSSSSSSS
Site 84S389SAAASSSSSSSSSSA
Site 85S390AAASSSSSSSSSSAS
Site 86S391AASSSSSSSSSSASP
Site 87S392ASSSSSSSSSSASPF
Site 88S393SSSSSSSSSSASPFP
Site 89S394SSSSSSSSSASPFPA
Site 90S395SSSSSSSSASPFPAS
Site 91S397SSSSSSASPFPASQA
Site 92S402SASPFPASQALPSYP
Site 93S407PASQALPSYPHSFPP
Site 94Y408ASQALPSYPHSFPPP
Site 95S411ALPSYPHSFPPPTSL
Site 96T416PHSFPPPTSLSVSNQ
Site 97S417HSFPPPTSLSVSNQP
Site 98S419FPPPTSLSVSNQPPK
Site 99S421PPTSLSVSNQPPKYT
Site 100Y427VSNQPPKYTQPSLPS
Site 101T428SNQPPKYTQPSLPSQ
Site 102S431PPKYTQPSLPSQAVW
Site 103S434YTQPSLPSQAVWSQG
Site 104S439LPSQAVWSQGPPPPP
Site 105Y448GPPPPPPYGRLLANS
Site 106S455YGRLLANSNAHPGPF
Site 107S465HPGPFPPSTGAQSTA
Site 108T466PGPFPPSTGAQSTAH
Site 109S470PPSTGAQSTAHPPVS
Site 110S502QQQHHGNSGPPPPGA
Site 111S518PHPLEGGSSHHAHPY
Site 112S519HPLEGGSSHHAHPYA
Site 113Y525SSHHAHPYAMSPSLG
Site 114S528HAHPYAMSPSLGSLR
Site 115S530HPYAMSPSLGSLRPY
Site 116S533AMSPSLGSLRPYPPG
Site 117Y537SLGSLRPYPPGPAHL
Site 118S549AHLPPPHSQVSYSQA
Site 119S552PPPHSQVSYSQAGPN
Site 120Y553PPHSQVSYSQAGPNG
Site 121S554PHSQVSYSQAGPNGP
Site 122S564GPNGPPVSSSSNSSS
Site 123S565PNGPPVSSSSNSSSS
Site 124S566NGPPVSSSSNSSSST
Site 125S567GPPVSSSSNSSSSTS
Site 126S569PVSSSSNSSSSTSQG
Site 127S570VSSSSNSSSSTSQGS
Site 128S571SSSSNSSSSTSQGSY
Site 129S572SSSNSSSSTSQGSYP
Site 130T573SSNSSSSTSQGSYPC
Site 131S574SNSSSSTSQGSYPCS
Site 132S577SSSTSQGSYPCSHPS
Site 133Y578SSTSQGSYPCSHPSP
Site 134S581SQGSYPCSHPSPSQG
Site 135S584SYPCSHPSPSQGPQG
Site 136S586PCSHPSPSQGPQGAP
Site 137Y594QGPQGAPYPFPPVPT
Site 138T601YPFPPVPTVTTSSAT
Site 139Y623VASSPAGYKTASPPG
Site 140T625SSPAGYKTASPPGPP
Site 141S627PAGYKTASPPGPPPY
Site 142Y634SPPGPPPYGKRAPSP
Site 143S640PYGKRAPSPGAYKTA
Site 144Y644RAPSPGAYKTATPPG
Site 145T646PSPGAYKTATPPGYK
Site 146T648PGAYKTATPPGYKPG
Site 147Y652KTATPPGYKPGSPPS
Site 148S656PPGYKPGSPPSFRTG
Site 149S659YKPGSPPSFRTGTPP
Site 150T662GSPPSFRTGTPPGYR
Site 151T664PPSFRTGTPPGYRGT
Site 152Y668RTGTPPGYRGTSPPA
Site 153T671TPPGYRGTSPPAGPG
Site 154S672PPGYRGTSPPAGPGT
Site 155T679SPPAGPGTFKPGSPT
Site 156S684PGTFKPGSPTVGPGP
Site 157T686TFKPGSPTVGPGPLP
Site 158S698PLPPAGPSGLPSLPP
Site 159S702AGPSGLPSLPPPPAA
Site 160S712PPPAAPASGPPLSAT
Site 161S717PASGPPLSATQIKQE
Site 162T719SGPPLSATQIKQEPA
Site 163Y729KQEPAEEYETPESPV
Site 164T731EPAEEYETPESPVPP
Site 165S734EEYETPESPVPPARS
Site 166S741SPVPPARSPSPPPKV
Site 167S743VPPARSPSPPPKVVD
Site 168S753PKVVDVPSHASQSAR
Site 169S756VDVPSHASQSARFNK
Site 170S758VPSHASQSARFNKHL
Site 171S771HLDRGFNSCARSDLY
Site 172Y778SCARSDLYFVPLEGS
Site 173S833KERELERSVKLAQEG
Site 174S848RAPVECPSLGPVPHR
Site 175S862RPPFEPGSAVATVPP
Site 176T875PPYLGPDTPALRTLS
Site 177S882TPALRTLSEYARPHV
Site 178Y884ALRTLSEYARPHVMS
Site 179S891YARPHVMSPGNRNHP
Site 180Y900GNRNHPFYVPLGAVD
Site 181Y919GYNVPALYSSDPAAR
Site 182S921NVPALYSSDPAARER
Site 183S950PGFEVKPSELEPLHG
Site 184S1011PALRPDMSYAERLAA
Site 185Y1012ALRPDMSYAERLAAE
Site 186T1085LASGSHLTRIPYPAG
Site 187Y1089SHLTRIPYPAGTLPN
Site 188T1093RIPYPAGTLPNPLLP
Site 189S1124PYRDLPASLSAPMSA
Site 190S1126RDLPASLSAPMSAAH
Site 191S1164HAHHPLHSVPLPAQE
Site 192Y1173PLPAQEDYYSHLKKE
Site 193Y1174LPAQEDYYSHLKKES
Site 194S1175PAQEDYYSHLKKESD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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