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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GYS2
Full Name:
Glycogen [starch] synthase, liver
Alias:
EC 2.4.1.11; Glycogen synthase, liver (starch)
Type:
Enzyme, glycogen synthesis
Mass (Da):
80989
Number AA:
703
UniProt ID:
P54840
International Prot ID:
IPI00008867
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030864
GO:0005829
GO:0043265
Uniprot
OncoNet
Molecular Function:
GO:0004373
GO:0042803
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0005978
GO:0009749
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
L
R
G
R
S
L
S
V
T
S
L
G
Site 2
S8
M
L
R
G
R
S
L
S
V
T
S
L
G
G
L
Site 3
T10
R
G
R
S
L
S
V
T
S
L
G
G
L
P
Q
Site 4
S11
G
R
S
L
S
V
T
S
L
G
G
L
P
Q
W
Site 5
Y45
T
N
K
V
G
G
I
Y
T
V
I
Q
T
K
A
Site 6
T46
N
K
V
G
G
I
Y
T
V
I
Q
T
K
A
K
Site 7
T50
G
I
Y
T
V
I
Q
T
K
A
K
T
T
A
D
Site 8
Y63
A
D
E
W
G
E
N
Y
F
L
I
G
P
Y
F
Site 9
Y69
N
Y
F
L
I
G
P
Y
F
E
H
N
M
K
T
Site 10
Y144
A
C
S
V
G
I
P
Y
H
D
R
E
A
N
D
Site 11
Y174
T
D
H
A
D
G
K
Y
V
V
A
Q
F
H
E
Site 12
T203
L
P
I
A
T
I
F
T
T
H
A
T
L
L
G
Site 13
Y221
C
A
A
N
I
D
F
Y
N
H
L
D
K
F
N
Site 14
Y239
E
A
G
E
R
Q
I
Y
H
R
Y
C
M
E
R
Site 15
T278
K
R
K
P
D
V
V
T
P
N
G
L
N
V
K
Site 16
Y405
E
K
F
G
K
K
L
Y
D
A
L
L
R
G
E
Site 17
T426
I
L
D
R
D
D
L
T
I
M
K
R
A
I
F
Site 18
S434
I
M
K
R
A
I
F
S
T
Q
R
Q
S
L
P
Site 19
T435
M
K
R
A
I
F
S
T
Q
R
Q
S
L
P
P
Site 20
S439
I
F
S
T
Q
R
Q
S
L
P
P
V
T
T
H
Site 21
S452
T
H
N
M
I
D
D
S
T
D
P
I
L
S
T
Site 22
T453
H
N
M
I
D
D
S
T
D
P
I
L
S
T
I
Site 23
S458
D
S
T
D
P
I
L
S
T
I
R
R
I
G
L
Site 24
S486
P
E
F
L
S
S
T
S
P
L
L
P
M
D
Y
Site 25
Y493
S
P
L
L
P
M
D
Y
E
E
F
V
R
G
C
Site 26
Y508
H
L
G
V
F
P
S
Y
Y
E
P
W
G
Y
T
Site 27
Y509
L
G
V
F
P
S
Y
Y
E
P
W
G
Y
T
P
Site 28
Y514
S
Y
Y
E
P
W
G
Y
T
P
A
E
C
T
V
Site 29
S559
I
V
D
R
R
F
R
S
P
D
D
S
C
N
Q
Site 30
S563
R
F
R
S
P
D
D
S
C
N
Q
L
T
K
F
Site 31
Y572
N
Q
L
T
K
F
L
Y
G
F
C
K
Q
S
R
Site 32
T589
R
I
I
Q
R
N
R
T
E
R
L
S
D
L
L
Site 33
S593
R
N
R
T
E
R
L
S
D
L
L
D
W
R
Y
Site 34
Y600
S
D
L
L
D
W
R
Y
L
G
R
Y
Y
Q
H
Site 35
Y604
D
W
R
Y
L
G
R
Y
Y
Q
H
A
R
H
L
Site 36
Y605
W
R
Y
L
G
R
Y
Y
Q
H
A
R
H
L
T
Site 37
T612
Y
Q
H
A
R
H
L
T
L
S
R
A
F
P
D
Site 38
S614
H
A
R
H
L
T
L
S
R
A
F
P
D
K
F
Site 39
T626
D
K
F
H
V
E
L
T
S
P
P
T
T
E
G
Site 40
S627
K
F
H
V
E
L
T
S
P
P
T
T
E
G
F
Site 41
T630
V
E
L
T
S
P
P
T
T
E
G
F
K
Y
P
Site 42
T631
E
L
T
S
P
P
T
T
E
G
F
K
Y
P
R
Site 43
Y636
P
T
T
E
G
F
K
Y
P
R
P
S
S
V
P
Site 44
S640
G
F
K
Y
P
R
P
S
S
V
P
P
S
P
S
Site 45
S641
F
K
Y
P
R
P
S
S
V
P
P
S
P
S
G
Site 46
S645
R
P
S
S
V
P
P
S
P
S
G
S
Q
A
S
Site 47
S647
S
S
V
P
P
S
P
S
G
S
Q
A
S
S
P
Site 48
S649
V
P
P
S
P
S
G
S
Q
A
S
S
P
Q
S
Site 49
S652
S
P
S
G
S
Q
A
S
S
P
Q
S
S
D
V
Site 50
S653
P
S
G
S
Q
A
S
S
P
Q
S
S
D
V
E
Site 51
S656
S
Q
A
S
S
P
Q
S
S
D
V
E
D
E
V
Site 52
S657
Q
A
S
S
P
Q
S
S
D
V
E
D
E
V
E
Site 53
Y668
D
E
V
E
D
E
R
Y
D
E
E
E
E
A
E
Site 54
S683
R
D
R
L
N
I
K
S
P
F
S
L
S
H
V
Site 55
S686
L
N
I
K
S
P
F
S
L
S
H
V
P
H
G
Site 56
S688
I
K
S
P
F
S
L
S
H
V
P
H
G
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation