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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
YWHAG
Full Name:
14-3-3 protein gamma
Alias:
1433G; 143G; KCIP-1; Protein kinase C inhibitor protein-1; Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Adapter/scaffold protein, 14-3-3 family
Mass (Da):
28303
Number AA:
247
UniProt ID:
P61981
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005159
GO:0005080
GO:0008426
PhosphoSite+
KinaseNET
Biological Process:
GO:0006469
GO:0045664
GO:0009966
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y20
L
A
E
Q
A
E
R
Y
D
D
M
A
A
A
M
Site 2
S38
T
E
L
N
E
P
L
S
N
E
E
R
N
L
L
Site 3
S46
N
E
E
R
N
L
L
S
V
A
Y
K
N
V
V
Site 4
Y49
R
N
L
L
S
V
A
Y
K
N
V
V
G
A
R
Site 5
S58
N
V
V
G
A
R
R
S
S
W
R
V
I
S
S
Site 6
S59
V
V
G
A
R
R
S
S
W
R
V
I
S
S
I
Site 7
S64
R
S
S
W
R
V
I
S
S
I
E
Q
K
T
S
Site 8
S65
S
S
W
R
V
I
S
S
I
E
Q
K
T
S
A
Site 9
S71
S
S
I
E
Q
K
T
S
A
D
G
N
E
K
K
Site 10
Y85
K
I
E
M
V
R
A
Y
R
E
K
I
E
K
E
Site 11
S113
N
Y
L
I
K
N
C
S
E
T
Q
Y
E
S
K
Site 12
T115
L
I
K
N
C
S
E
T
Q
Y
E
S
K
V
F
Site 13
Y117
K
N
C
S
E
T
Q
Y
E
S
K
V
F
Y
L
Site 14
S119
C
S
E
T
Q
Y
E
S
K
V
F
Y
L
K
M
Site 15
Y123
Q
Y
E
S
K
V
F
Y
L
K
M
K
G
D
Y
Site 16
Y130
Y
L
K
M
K
G
D
Y
Y
R
Y
L
A
E
V
Site 17
Y131
L
K
M
K
G
D
Y
Y
R
Y
L
A
E
V
A
Site 18
Y133
M
K
G
D
Y
Y
R
Y
L
A
E
V
A
T
G
Site 19
T139
R
Y
L
A
E
V
A
T
G
E
K
R
A
T
V
Site 20
T145
A
T
G
E
K
R
A
T
V
V
E
S
S
E
K
Site 21
S150
R
A
T
V
V
E
S
S
E
K
A
Y
S
E
A
Site 22
S155
E
S
S
E
K
A
Y
S
E
A
H
E
I
S
K
Site 23
T168
S
K
E
H
M
Q
P
T
H
P
I
R
L
G
L
Site 24
Y179
R
L
G
L
A
L
N
Y
S
V
F
Y
Y
E
I
Site 25
S180
L
G
L
A
L
N
Y
S
V
F
Y
Y
E
I
Q
Site 26
Y184
L
N
Y
S
V
F
Y
Y
E
I
Q
N
A
P
E
Site 27
T199
Q
A
C
H
L
A
K
T
A
F
D
D
A
I
A
Site 28
T210
D
A
I
A
E
L
D
T
L
N
E
D
S
Y
K
Site 29
S215
L
D
T
L
N
E
D
S
Y
K
D
S
T
L
I
Site 30
Y216
D
T
L
N
E
D
S
Y
K
D
S
T
L
I
M
Site 31
S219
N
E
D
S
Y
K
D
S
T
L
I
M
Q
L
L
Site 32
T220
E
D
S
Y
K
D
S
T
L
I
M
Q
L
L
R
Site 33
T231
Q
L
L
R
D
N
L
T
L
W
T
S
D
Q
Q
Site 34
S235
D
N
L
T
L
W
T
S
D
Q
Q
D
D
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation