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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCT2
Full Name:
T-complex protein 1 subunit beta
Alias:
CCTB; CCT-beta; Chaperonin containing t-complex polypeptide 1, subunit 2; T-complex protein 1, beta; TCP-1-beta; TCPB
Type:
Chaperone
Mass (Da):
57488
Number AA:
535
UniProt ID:
P78371
International Prot ID:
IPI00297779
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005730
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
GO:0008152
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
L
S
L
A
P
V
N
Site 2
T23
A
D
E
E
R
A
E
T
A
R
L
T
S
F
I
Site 3
T27
R
A
E
T
A
R
L
T
S
F
I
G
A
I
A
Site 4
S28
A
E
T
A
R
L
T
S
F
I
G
A
I
A
I
Site 5
T42
I
G
D
L
V
K
S
T
L
G
P
K
G
M
D
Site 6
S54
G
M
D
K
I
L
L
S
S
G
R
D
A
S
L
Site 7
S60
L
S
S
G
R
D
A
S
L
M
V
T
N
D
G
Site 8
T99
D
D
E
V
G
D
G
T
T
S
V
T
V
L
A
Site 9
S115
E
L
L
R
E
A
E
S
L
I
A
K
K
I
H
Site 10
T134
I
A
G
W
R
E
A
T
K
A
A
R
E
A
L
Site 11
S143
A
A
R
E
A
L
L
S
S
A
V
D
H
G
S
Site 12
S144
A
R
E
A
L
L
S
S
A
V
D
H
G
S
D
Site 13
S150
S
S
A
V
D
H
G
S
D
E
V
K
F
R
Q
Site 14
T165
D
L
M
N
I
A
G
T
T
L
S
S
K
L
L
Site 15
T166
L
M
N
I
A
G
T
T
L
S
S
K
L
L
T
Site 16
S168
N
I
A
G
T
T
L
S
S
K
L
L
T
H
H
Site 17
S169
I
A
G
T
T
L
S
S
K
L
L
T
H
H
K
Site 18
T173
T
L
S
S
K
L
L
T
H
H
K
D
H
F
T
Site 19
S254
D
K
I
K
I
F
G
S
R
V
R
V
D
S
T
Site 20
S260
G
S
R
V
R
V
D
S
T
A
K
V
A
E
I
Site 21
T261
S
R
V
R
V
D
S
T
A
K
V
A
E
I
E
Site 22
Y297
F
I
N
R
Q
L
I
Y
N
Y
P
E
Q
L
F
Site 23
Y299
N
R
Q
L
I
Y
N
Y
P
E
Q
L
F
G
A
Site 24
S333
V
T
G
G
E
I
A
S
T
F
D
H
P
E
L
Site 25
T334
T
G
G
E
I
A
S
T
F
D
H
P
E
L
V
Site 26
T379
T
I
V
L
R
G
A
T
Q
Q
I
L
D
E
A
Site 27
S404
L
A
Q
T
V
K
D
S
R
T
V
Y
G
G
G
Site 28
T406
Q
T
V
K
D
S
R
T
V
Y
G
G
G
C
S
Site 29
Y408
V
K
D
S
R
T
V
Y
G
G
G
C
S
E
M
Site 30
T428
V
T
Q
L
A
N
R
T
P
G
K
E
A
V
A
Site 31
S470
A
Q
L
R
A
A
H
S
E
G
N
T
T
A
G
Site 32
T474
A
A
H
S
E
G
N
T
T
A
G
L
D
M
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation