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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EFNB1
Full Name:
Ephrin-B1
Alias:
CEK5 ligand; CEK5 receptor ligand; CEK5-L; CEL5-L; CFNS; EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; Ephrin-B1: EPH-related receptor tyrosine kinase ligand 2: EFL-3; EPL2; EPLG2; Kinase ephrin-B1; LERK2; LERK-2; STRA1; STRA1 protein
Type:
Ligand, receptor tyrosine kinase
Mass (Da):
38007
Number AA:
346
UniProt ID:
P98172
International Prot ID:
IPI00024307
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
GO:0005625
GO:0045202
Uniprot
OncoNet
Molecular Function:
GO:0046875
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0007267
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y79
P
Y
E
Y
Y
K
L
Y
L
V
R
P
E
Q
A
Site 2
S218
T
V
N
Q
E
E
K
S
G
P
G
A
S
G
G
Site 3
S223
E
K
S
G
P
G
A
S
G
G
S
S
G
D
P
Site 4
S226
G
P
G
A
S
G
G
S
S
G
D
P
D
G
F
Site 5
S227
P
G
A
S
G
G
S
S
G
D
P
D
G
F
F
Site 6
T273
R
K
R
H
R
K
H
T
Q
Q
R
A
A
A
L
Site 7
S281
Q
Q
R
A
A
A
L
S
L
S
T
L
A
S
P
Site 8
S283
R
A
A
A
L
S
L
S
T
L
A
S
P
K
G
Site 9
T284
A
A
A
L
S
L
S
T
L
A
S
P
K
G
G
Site 10
S287
L
S
L
S
T
L
A
S
P
K
G
G
S
G
T
Site 11
T294
S
P
K
G
G
S
G
T
A
G
T
E
P
S
D
Site 12
Y313
L
R
T
T
E
N
N
Y
C
P
H
Y
E
K
V
Site 13
Y317
E
N
N
Y
C
P
H
Y
E
K
V
S
G
D
Y
Site 14
S321
C
P
H
Y
E
K
V
S
G
D
Y
G
H
P
V
Site 15
Y324
Y
E
K
V
S
G
D
Y
G
H
P
V
Y
I
V
Site 16
Y329
G
D
Y
G
H
P
V
Y
I
V
Q
E
M
P
P
Site 17
S338
V
Q
E
M
P
P
Q
S
P
A
N
I
Y
Y
K
Site 18
Y343
P
Q
S
P
A
N
I
Y
Y
K
V
_
_
_
_
Site 19
Y344
Q
S
P
A
N
I
Y
Y
K
V
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation