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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Pax2
Full Name:
Paired box protein Pax-2
Alias:
paired box 2; PAX-2
Type:
DNA binding protein
Mass (Da):
44706
Number AA:
417
UniProt ID:
Q02962
International Prot ID:
IPI00304452
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0034451
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0007409
GO:0045449
GO:0006366
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S55
G
V
R
P
C
D
I
S
R
Q
L
R
V
S
H
Site 2
S61
I
S
R
Q
L
R
V
S
H
G
C
V
S
K
I
Site 3
Y72
V
S
K
I
L
G
R
Y
Y
E
T
G
S
I
K
Site 4
Y73
S
K
I
L
G
R
Y
Y
E
T
G
S
I
K
P
Site 5
S77
G
R
Y
Y
E
T
G
S
I
K
P
G
V
I
G
Site 6
T92
G
S
K
P
K
V
A
T
P
K
V
V
D
K
I
Site 7
Y102
V
V
D
K
I
A
E
Y
K
R
Q
N
P
T
M
Site 8
T128
E
G
I
C
D
N
D
T
V
P
S
V
S
S
I
Site 9
S131
C
D
N
D
T
V
P
S
V
S
S
I
N
R
I
Site 10
T150
V
Q
Q
P
F
H
P
T
P
D
G
A
G
T
G
Site 11
S168
P
G
H
T
I
V
P
S
T
A
S
P
P
V
S
Site 12
T169
G
H
T
I
V
P
S
T
A
S
P
P
V
S
S
Site 13
S175
S
T
A
S
P
P
V
S
S
A
S
N
D
P
V
Site 14
S176
T
A
S
P
P
V
S
S
A
S
N
D
P
V
G
Site 15
S178
S
P
P
V
S
S
A
S
N
D
P
V
G
S
Y
Site 16
S184
A
S
N
D
P
V
G
S
Y
S
I
N
G
I
L
Site 17
S196
G
I
L
G
I
P
R
S
N
G
E
K
R
K
R
Site 18
Y209
K
R
D
E
V
E
V
Y
T
D
P
A
H
I
R
Site 19
T226
G
G
L
H
L
V
W
T
L
R
D
V
S
E
G
Site 20
S231
V
W
T
L
R
D
V
S
E
G
S
V
P
N
G
Site 21
S234
L
R
D
V
S
E
G
S
V
P
N
G
D
S
Q
Site 22
S240
G
S
V
P
N
G
D
S
Q
S
G
V
D
S
L
Site 23
S242
V
P
N
G
D
S
Q
S
G
V
D
S
L
R
K
Site 24
S246
D
S
Q
S
G
V
D
S
L
R
K
H
L
R
A
Site 25
T255
R
K
H
L
R
A
D
T
F
T
Q
Q
Q
L
E
Site 26
T257
H
L
R
A
D
T
F
T
Q
Q
Q
L
E
A
L
Site 27
S272
D
R
V
F
E
R
P
S
Y
P
D
V
F
Q
A
Site 28
Y273
R
V
F
E
R
P
S
Y
P
D
V
F
Q
A
S
Site 29
S285
Q
A
S
E
H
I
K
S
E
Q
G
N
E
Y
S
Site 30
Y291
K
S
E
Q
G
N
E
Y
S
L
P
A
L
T
P
Site 31
S292
S
E
Q
G
N
E
Y
S
L
P
A
L
T
P
G
Site 32
T297
E
Y
S
L
P
A
L
T
P
G
L
D
E
V
K
Site 33
S305
P
G
L
D
E
V
K
S
S
L
S
A
S
T
N
Site 34
S306
G
L
D
E
V
K
S
S
L
S
A
S
T
N
P
Site 35
S308
D
E
V
K
S
S
L
S
A
S
T
N
P
E
L
Site 36
S310
V
K
S
S
L
S
A
S
T
N
P
E
L
G
S
Site 37
S317
S
T
N
P
E
L
G
S
N
V
S
G
T
Q
T
Site 38
S320
P
E
L
G
S
N
V
S
G
T
Q
T
Y
P
V
Site 39
T324
S
N
V
S
G
T
Q
T
Y
P
V
V
T
G
R
Site 40
Y325
N
V
S
G
T
Q
T
Y
P
V
V
T
G
R
D
Site 41
T336
T
G
R
D
M
A
S
T
T
L
P
G
Y
P
P
Site 42
T337
G
R
D
M
A
S
T
T
L
P
G
Y
P
P
H
Site 43
Y341
A
S
T
T
L
P
G
Y
P
P
H
V
P
P
T
Site 44
T348
Y
P
P
H
V
P
P
T
G
Q
G
S
Y
P
T
Site 45
S352
V
P
P
T
G
Q
G
S
Y
P
T
S
T
L
A
Site 46
Y353
P
P
T
G
Q
G
S
Y
P
T
S
T
L
A
G
Site 47
S356
G
Q
G
S
Y
P
T
S
T
L
A
G
M
V
P
Site 48
T357
Q
G
S
Y
P
T
S
T
L
A
G
M
V
P
G
Site 49
S365
L
A
G
M
V
P
G
S
E
F
S
G
N
P
Y
Site 50
S368
M
V
P
G
S
E
F
S
G
N
P
Y
S
H
P
Site 51
Y372
S
E
F
S
G
N
P
Y
S
H
P
Q
Y
T
A
Site 52
Y377
N
P
Y
S
H
P
Q
Y
T
A
Y
N
E
A
W
Site 53
Y380
S
H
P
Q
Y
T
A
Y
N
E
A
W
R
F
S
Site 54
S387
Y
N
E
A
W
R
F
S
N
P
A
L
L
S
S
Site 55
S393
F
S
N
P
A
L
L
S
S
P
Y
Y
Y
S
A
Site 56
S394
S
N
P
A
L
L
S
S
P
Y
Y
Y
S
A
A
Site 57
Y397
A
L
L
S
S
P
Y
Y
Y
S
A
A
P
R
G
Site 58
Y398
L
L
S
S
P
Y
Y
Y
S
A
A
P
R
G
S
Site 59
S399
L
S
S
P
Y
Y
Y
S
A
A
P
R
G
S
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation