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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NMDAR1 (Glutamate)
Full Name:
Glutamate [NMDA] receptor subunit zeta-1
Alias:
N-methyl-D-aspartate receptor subunit NR1
Type:
Channel protein
Mass (Da):
105373
Number AA:
938
UniProt ID:
Q05586
International Prot ID:
IPI00013915
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0017146
GO:0030054
GO:0030425
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005516
GO:0005234
PhosphoSite+
KinaseNET
Biological Process:
GO:0055074
GO:0006812
GO:0035235
Phosida
TranscriptoNet
STRING
Kinexus Products
Glutamate receptor ionotropic, NMDA 1 pan-specific antibody AB-NN264-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN264-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
V
N
I
G
A
V
L
S
T
R
K
H
E
Q
M
Site 2
S55
Q
A
N
K
R
H
G
S
W
K
I
Q
L
N
A
Site 3
S93
Q
V
Y
A
I
L
V
S
H
P
P
T
P
N
D
Site 4
T97
I
L
V
S
H
P
P
T
P
N
D
H
F
T
P
Site 5
T103
P
T
P
N
D
H
F
T
P
T
P
V
S
Y
T
Site 6
T105
P
N
D
H
F
T
P
T
P
V
S
Y
T
A
G
Site 7
S126
L
G
L
T
T
R
M
S
I
Y
S
D
K
S
I
Site 8
Y128
L
T
T
R
M
S
I
Y
S
D
K
S
I
H
L
Site 9
S129
T
T
R
M
S
I
Y
S
D
K
S
I
H
L
S
Site 10
S132
M
S
I
Y
S
D
K
S
I
H
L
S
F
L
R
Site 11
S136
S
D
K
S
I
H
L
S
F
L
R
T
V
P
P
Site 12
T140
I
H
L
S
F
L
R
T
V
P
P
Y
S
H
Q
Site 13
Y144
F
L
R
T
V
P
P
Y
S
H
Q
S
S
V
W
Site 14
S145
L
R
T
V
P
P
Y
S
H
Q
S
S
V
W
F
Site 15
S168
N
H
I
I
L
L
V
S
D
D
H
E
G
R
A
Site 16
T182
A
A
Q
K
R
L
E
T
L
L
E
E
R
E
S
Site 17
S189
T
L
L
E
E
R
E
S
K
A
E
K
V
L
Q
Site 18
T230
A
S
E
D
D
A
A
T
V
Y
R
A
A
A
M
Site 19
S255
L
V
G
E
R
E
I
S
G
N
A
L
R
Y
A
Site 20
S278
L
I
N
G
K
N
E
S
A
H
I
S
D
A
V
Site 21
T302
L
L
E
K
E
N
I
T
D
P
P
R
G
C
V
Site 22
T317
G
N
T
N
I
W
K
T
G
P
L
F
K
R
V
Site 23
S328
F
K
R
V
L
M
S
S
K
Y
A
D
G
V
T
Site 24
Y330
R
V
L
M
S
S
K
Y
A
D
G
V
T
G
R
Site 25
T335
S
K
Y
A
D
G
V
T
G
R
V
E
F
N
E
Site 26
Y351
G
D
R
K
F
A
N
Y
S
I
M
N
L
Q
N
Site 27
T386
I
I
W
P
G
G
E
T
E
K
P
R
G
Y
Q
Site 28
Y392
E
T
E
K
P
R
G
Y
Q
M
S
T
R
L
K
Site 29
S395
K
P
R
G
Y
Q
M
S
T
R
L
K
I
V
T
Site 30
Y410
I
H
Q
E
P
F
V
Y
V
K
P
T
L
S
D
Site 31
T414
P
F
V
Y
V
K
P
T
L
S
D
G
T
C
K
Site 32
S416
V
Y
V
K
P
T
L
S
D
G
T
C
K
E
E
Site 33
T425
G
T
C
K
E
E
F
T
V
N
G
D
P
V
K
Site 34
T442
I
C
T
G
P
N
D
T
S
P
G
S
P
R
H
Site 35
S443
C
T
G
P
N
D
T
S
P
G
S
P
R
H
T
Site 36
S446
P
N
D
T
S
P
G
S
P
R
H
T
V
P
Q
Site 37
T450
S
P
G
S
P
R
H
T
V
P
Q
C
C
Y
G
Site 38
Y474
A
R
T
M
N
F
T
Y
E
V
H
L
V
A
D
Site 39
T518
D
M
I
V
A
P
L
T
I
N
N
E
R
A
Q
Site 40
Y526
I
N
N
E
R
A
Q
Y
I
E
F
S
K
P
F
Site 41
S549
V
K
K
E
I
P
R
S
T
L
D
S
F
M
Q
Site 42
T550
K
K
E
I
P
R
S
T
L
D
S
F
M
Q
P
Site 43
S553
I
P
R
S
T
L
D
S
F
M
Q
P
F
Q
S
Site 44
S593
F
G
R
F
K
V
N
S
E
E
E
E
E
D
A
Site 45
T602
E
E
E
E
D
A
L
T
L
S
S
A
M
W
F
Site 46
S604
E
E
D
A
L
T
L
S
S
A
M
W
F
S
W
Site 47
T665
D
R
P
E
E
R
I
T
G
I
N
D
P
R
L
Site 48
S676
D
P
R
L
R
N
P
S
D
K
F
I
Y
A
T
Site 49
Y681
N
P
S
D
K
F
I
Y
A
T
V
K
Q
S
S
Site 50
T683
S
D
K
F
I
Y
A
T
V
K
Q
S
S
V
D
Site 51
Y692
K
Q
S
S
V
D
I
Y
F
R
R
Q
V
E
L
Site 52
Y711
R
H
M
E
K
H
N
Y
E
S
A
A
E
A
I
Site 53
S766
G
I
G
M
R
K
D
S
P
W
K
Q
N
V
S
Site 54
S773
S
P
W
K
Q
N
V
S
L
S
I
L
K
S
H
Site 55
S775
W
K
Q
N
V
S
L
S
I
L
K
S
H
E
N
Site 56
S779
V
S
L
S
I
L
K
S
H
E
N
G
F
M
E
Site 57
Y795
L
D
K
T
W
V
R
Y
Q
E
C
D
S
R
S
Site 58
S800
V
R
Y
Q
E
C
D
S
R
S
N
A
P
A
T
Site 59
S802
Y
Q
E
C
D
S
R
S
N
A
P
A
T
L
T
Site 60
T807
S
R
S
N
A
P
A
T
L
T
F
E
N
M
A
Site 61
Y837
L
I
F
I
E
I
A
Y
K
R
H
K
D
A
R
Site 62
S867
K
N
L
Q
D
R
K
S
G
R
A
E
P
D
P
Site 63
T879
P
D
P
K
K
K
A
T
F
R
A
I
T
S
T
Site 64
T886
T
F
R
A
I
T
S
T
L
A
S
S
F
K
R
Site 65
S889
A
I
T
S
T
L
A
S
S
F
K
R
R
R
S
Site 66
S890
I
T
S
T
L
A
S
S
F
K
R
R
R
S
S
Site 67
S896
S
S
F
K
R
R
R
S
S
K
D
T
S
T
G
Site 68
S897
S
F
K
R
R
R
S
S
K
D
T
S
T
G
G
Site 69
T900
R
R
R
S
S
K
D
T
S
T
G
G
G
R
G
Site 70
S901
R
R
S
S
K
D
T
S
T
G
G
G
R
G
A
Site 71
T902
R
S
S
K
D
T
S
T
G
G
G
R
G
A
L
Site 72
T915
A
L
Q
N
Q
K
D
T
V
L
P
R
R
A
I
Site 73
S933
E
G
Q
L
Q
L
C
S
R
H
R
E
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation