PhosphoNET

           
Protein Info 
   
Short Name:  TP2
Full Name:  Nuclear transition protein 2
Alias:  During histone to protamine replacement; STP2; TNP2; TP-2; Transition protein 2
Type:  DNA binding protein
Mass (Da):  15641
Number AA:  138
UniProt ID:  Q05952
International Prot ID:  IPI00016783
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0000786  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:  GO:0030154  GO:0007275  GO:0007283 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T11QTHSLPITHTQLHSN
Site 2T13HSLPITHTQLHSNSQ
Site 3S17ITHTQLHSNSQPQSR
Site 4S19HTQLHSNSQPQSRTC
Site 5T27QPQSRTCTRHCQTFS
Site 6S40FSQSCRQSHRGSRSQ
Site 7S44CRQSHRGSRSQSSSQ
Site 8S46QSHRGSRSQSSSQSP
Site 9S48HRGSRSQSSSQSPAS
Site 10S49RGSRSQSSSQSPASH
Site 11S50GSRSQSSSQSPASHR
Site 12S52RSQSSSQSPASHRNP
Site 13S55SSSQSPASHRNPTGA
Site 14T60PASHRNPTGAHSSSG
Site 15S64RNPTGAHSSSGHQSQ
Site 16S65NPTGAHSSSGHQSQS
Site 17S66PTGAHSSSGHQSQSP
Site 18S70HSSSGHQSQSPNTSP
Site 19S72SSGHQSQSPNTSPPP
Site 20S76QSQSPNTSPPPKRHK
Site 21T85PPKRHKKTMNSHHSP
Site 22S88RHKKTMNSHHSPMRP
Site 23S91KTMNSHHSPMRPTIL
Site 24Y126AKRIQQVYKTKTRSS
Site 25T128RIQQVYKTKTRSSGW
Site 26T130QQVYKTKTRSSGWKS
Site 27S132VYKTKTRSSGWKSN_
Site 28S133YKTKTRSSGWKSN__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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